2002, Number 6
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Gac Med Mex 2002; 138 (6)
Cyanoacrylate compared with traditional surgery in tension-free incision closure.
Orozco-Razón LF, Millán-Guerrero RO, Vera-Rodríguez SE
Language: Spanish
References: 31
Page: 505-509
PDF size: 34.19 Kb.
ABSTRACT
Objective: To investigate the efficiency of cyanoacrylate in closing tension-free incisions in out-patient surgery compared with traditional suturing methods. Patient and methods: A single, blind, clinical study was carried out on 60 patients divided into two groups. Group 1 (n=30) received one or two drops of cyanoacrylate directly on the incision. Control (Group 2) (n=32) received traditional nylon suturing. Both groups were evaluated after 21 days of incision closing. Statistical differences in baseline characteristics between study treatment groups were assessed with χ
2 and t tests. All p values are two-sided.
Results: There was no significant difference between the two groups in age, gender, or incision length. Length of time for surgical incision to close was less in Group I, significant difference p ‹0.0001. There was also a significant difference in aesthetics in Group I. There was no significant difference in any remaining variable, such as suture dehiscence and adequate border coaption.
Conclusion: Our study showed cyanoacrylate to be more efficient and advantageous in closing of incisions in out-patient surgery than traditional suturing methods. Although we do not pretend to substitute these methods, we recommend the use of cyanoacrylate in closing tension-free incisions in certain patients following rules of usage and practiced by experts.
REFERENCES
Peacock E Jr. Cicatrización y cuidados de las heridas. En: Principios de cirugía. Schwartz SS, Daly FG (Eds), séptima edición. México: McGraw-Hill; 2000. p. 267-86.
Galil K, Schofield I, Wright G. Scientific effect of N-butyl-2cyanoacrylate (histoacryl Blue) on the healing of skin wounds. J Can Dental Assoc. 1984;50:565-569.
Brown PN, McGuff, Nooryl HS. Comparison of N octyl-cyanoacrylate Vs suture in the stabilization of cartilage grafts. Arch-Otolaryngol Head and Neck Surg 1996;122:873-877.
Nakkada Y, Fattal E, Foulquier M, Coover P. Pharmacokinetics and distribution of oligonucleotids absorbed in to ploy (isobutylcyanoacrylate) nanoparticles after intravenous administration in mice. Pharm Res 1996;13:38-43.
Veludios A et al. Cyanoacrylate tissue adhesive in blepharoplasty. Ophtal Plast Reconst Surg 1996;12:89-97.
Chappelow CC, Byerly TJ, lnzino CS, Millich F, Eick JD. Design and development of isocyanoacrylates as dental adhesives. J Dental Res 1996;75:761-7.
Alio JL, Mullet-ME, García JC. Use of cyanoacrylate tissue adhesive in small incision cataract surgery. Ophthal Surg Lasers 1996;27:270-274.
Bodaghi, Levy C, Votan P, Hoang Wuan T. Value of cyanocrylate tissue adhesives in peripheral corneal ulcers of inflammatory origin. J Fr Ophthalmol 1996;19:2-32.
Jones C, Laurence BH, Faulker KW, Culling GL. Closure of a benign bronchoesophageal fistula by endoscopic injection of bovine collagen, cyanoacrylate glue and gel foam. Aust N Z J Surg 1996;66;53-55.
Mokiya T, lshii O, Yamazaki. Surgical treatment for subacute left ventricular free wall rupture complicating acute myocardial infraction-pericardial patch gluing method. Nippon Kiobu Geka Gakkai Zassahi 1996;44:896-910.
Jutaba R, Jensen M. Management of upper gastrointestinal bleeding in the patient with chronic liver disease. Med Clin North Am 1996;80:1035-1068.
D’Imperio N, Piemontese A, Baroncini D, Billie P. Evaluation of undiluted N-butyl-2-cyanoacrylate in the endoscopic gastrointestinal tract varices. Endoscopy 1996;28: 239-243.
Cotten A, Dearmond H, Corter B. Preoperative percutaneous injection of methylcyanoacrylate in vertebral hemangiomas. Am J Neuroradiol 1996;17:137-142.
Zhai H, Maibach HI. Effect of barrier creams: human skin in vivo. Contact Dermatitis 1996;35:92-96.
Fresta M, Cavallaro G, Giammona G, Wehri E, Puglidsi G. Preparation and characterization of polyethyl-2 cyanoacrylate nanocapsules containing antiepileptic drugs. Biomaterial 1996;17:751-758.
Liebelt E. Current concepts in laceration repair. Curr Opin Pediatr 1997;9:459-464.
Mizrarhi S. Use of tissue adhesive in repair lacerations in children. J Ped Surg 1988;23:312-313.
Bruns T, Simon H, McLario D, et al. Laceration repair using a tissue adhesive in a children’s emergency department. Pediatrics 1996;98:673-675.
Reghel LF. Cyanoacrylate tissue adhesive and facial lacerations. BMJ 1989;299:1217-1218.
Quinn J, Weils G, Sutcliffe T, et al. A randomized trial comparing octylcyanoacrylate tissue adhesive and sutures in the management of lacerations. JAMA 1997;277:1527-1530.
Toriumi, Dean M, Watson. Cyanoacrylate tissue adhesives for superficial skin closure. Curr Opin Otolaryngol Head & Neck Surg 1999;7:214.
Bazell GM, Boschert MT, Concannon MJ, Puckett CL. Reduction mammoplasty incision closure with octyl-2-cyanoacrylate. Am Coll Surg 2000;191(Supple 1).
Valenzuela CS. Comparación de material de sutura y cianoacrilato para cierre de heridas cutáneas. Tesis de cirugía plástica y reconstructiva. HGZ 1 IMSS y Hosp. Manuel Gea Glez.; S.S.A 1989.
Díaz Barreiro G. Experiencia en 10 casos de sutura cutánea utilizando el adhesivo etilcianoacrilato, informe inicial. Gin Obs Mex 1995;63:10-14.
Farouk et al. Preliminary experience with buthyl-2-cyanoacrylate adhesive tension free inguinal hernia repair. Br J Surg 1996;83:1100.
Gorospe et al. Cierre de la piel con cianoacrilato en las heridas quirúrgicas después de la oclusión tubárica bilateral. Gin Obs Mex. 1997;65:447-450.
Kopferschimtkubier MC, Stenger R, Blaumeiser MM. Asthma, rinitis and urticaria following occupational exposure to cyanoacrylater glues. Rev Mal Respir 1996;13:395-397.
Giray CBN, et al. Comparison of silk sutures and n-butyl-2-cyanoacrylate on the healing of skin wounds. A pilot study. Aust Dent 1995;40:43-45.
De Bono R. A simple inexpensive method for precise application of cyanoacylate tissue adhesive. Plast Reconstr Surg 1997;100:447-450.
Quinn; Wells G, Sut Cliffe T. A randomized trial comparing octyl cyanoacrylate tissue adhesive and sutures in the management of laceration. JAMA 1997;277:1527.
Applebaum J, Zalut T, Applebaum D. The use of tissue adhesion for traumatic laceration repair in the emergency department. Ann Emerg Med 1993; 22:1190-1192.