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2017, Number 2

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Rev Mex Angiol 2017; 45 (2)

Frecuencia bacteriana y sensibilidad antibiótica in vitro en pacientes con diagnóstico de pie diabético en el Hospital Central del Estado de Chihuahua, Chihuahua

Sáenz-Talavera R, Flores-Ramírez C, Contreras-Rabelo SG

Language: Spanish
References: 13
Page: 57-63
PDF size: 146.09 Kb.


ABSTRACT

Objective. To determine the bacterial frequency and antimicrobial susceptibility in culture and antibiogram in samples from patients with diabetic foot infection.
Methods. We selected the files that met the inclusion criteria in the population of patients admitted with diagnosis of infected diabetic foot, from January 2015 to July 2016 in HCE. Data were collected for statistical analysis.
Results. A total of 102 patients were included. Twenty-two different species of bacteria were isolated, the three main ones were Staphylococcus aureus, Escherichia coli and Enterococcus faecalis. The antibiotic sensitivity for the three most frequent Gram positive bacteria isolated compared to the empirical therapy based on ciprofloxacin and clindamycin was low (‹ 50%), for the three most frequently isolated Gram negative bacteria, empirical therapy based on ceftriaxone or ciprofloxacin was of: Escheri- chia coli, 22.7 and 22.7%; Klebsiella pneumoniae, 37.5 and 50%; Proteus mirabilis, 57.1 and 28.6%, respectively.
Conclusions. The antibiotics that showed the highest sensitivity to the most frequently isolated Gram positive bacteria were, vancomycin, linezolid and tigecycline, whereas for gram negative bacteria a greater sensitivity was observed in the group of carbapenems and gentamicin. The empirical therapy used regularly showed low sensitivity to the isolated microorganisms, so it is recommended a readjustment of antibiotic upon having the record of the antibiogram.


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