2017, Number 3
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Correo Científico Médico 2017; 21 (3)
Clinical epidemiological description of conglobate acne in Holguin and Granma provinces
Rojas BR, Martínez VG, Santos FN, Mederos AL, Tamayo CV, Álvarez OJ
Language: Spanish
References: 12
Page: 693-705
PDF size: 505.29 Kb.
ABSTRACT
Introduction: acne is one of the most frequent dermatology affections in medical practices, and conglobate acne is characterized as uncommon. The genesis of this illness is complicated and depends on the interaction of many factors, for example the genetic factors.
Objective: to describe histopatological, epidemiological and clinically the conglobate acne incidence in some families from Holguín–Granma regions.
Method: a case series study was carried out for the period from January 2000 to December 2014. The environmental context where the patients were developed was described. The patients were examined to make the family tree, clinical follow-up of lesions and biopsy for histopathological study.
Results: the disease affected women and men before the age of 21. The nodule cystic lesions were the first ones. Nodules, macrocomedones, fistulized conglomerates, scar flanges had little resolution capacity with conventional treatment and reached large sizes as the evolution time advanced. The lesions were distributed with a preference in the back, underarms and glutes. Histopathological changes were hyperkeratosis with corneal plugs, follicular alterations and the presence of epidermal inclusion cysts with fistulous pathways. The inheritance behaved autonomously dominant. The areas with the highest number of cases were those located on the banks of the Cauto River and in surrounding areas.
Conclusions: the diagnostic elements of the disease, both clinical and epidemiological, as well as histopathological, were defined.
REFERENCES
Kaminsky A. Síndrome de oclusión de los folículos terminales (Acné Inversa). Act Terap Dermatol. 2007[citado 12 abr 2009]; 30:78-90.Disponible en: http://www.atdermae.com/pdfs/atd_30_02_02.pdf
Veja J, Sánchez Velicia L, Pozo T.Efficacy of Etanercept in the Treatment of Acne Conglobata. Actas Dermosifiliogr.2010 [citado 12 abr 2012]; 101(6):553-554. Disponible en: http://www.sciencedirect.com/science/article/pii/S000173101000219X
Esteban F. Consenso sobre Acné. Buenos Aires: Sociedad Argentina de Dermatología. 2005 [citado 12 abr 2009]. Disponible en: http://www.sad.org.ar/wp-content/uploads/2016/04/acne.pdf
Mehra T, Borelli C, Burgdorf W, Röcken M, Schaller M. Treatment of Severe Acne with Low-dose Isotretinoin. Acta DermVenereol.2012 [citado 12 abr 2014]; 92(3):247–248. Disponible en: https://www.medicaljournals.se/acta/content_files/download.php?doi=10.2340/00015555-1325
Díaz García MA. Dermatitis seborreica, acné vulgar y rosácea.En: Manzur Katrib J, Díaz Almeida J, Cortés Hernández M, Ortiz González PR, Sagaró Delgado B, Abreu Danie A. Dermatología. La Habana: Ciencias Médicas; 2002.p. 110-120.
Wolf K, Allen Jonson R, Suurmand D. Enfermedades de las glándulas sebáceas y apocrinas. En: Dermatología. Atlas en color y sinopsis de dermatología clínica. 5taed. España: Mc Graw – Hill. Interamericana; 2008.p.2–14.
Cuba. Oficina nacional de Estadística e Información. Censo de población y vivienda 2012. Resumen adelantado. Resultados definitivos e indicadores seleccionados en Cuba, provincias y municipios. La Habana: ONEI; 2012[citado 16 sep 2015].Disponible en: http://www.one.cu/resumenadelantadocenso2012.htm
Prasad PV, Kaviarasan PK, Joseph JM, Madhuri S, Viswanathan P. Familial acne inversa with acne conglobata in three generations. Indian J Dermatol Venereol Leprol.2008 [citado 12 abr 2009]; 74(3):283-285. Disponible en: http://www.ijdvl.com/article.asp?issn=0378-6323;year=2008;volume=74;issue=3;spage=283;epage=285;aulast=Prasad
Bayamo MN. Informe de la evolución ambiental del Programa de Rehabilitación de La Cuenca del Cauto 2008-2009. Granma: Recursos Hidráulicos; 2009.
Naderi AS, Reilly RF. Hereditary etiologies of hypomagnesemia. Nat Clin Pract Nephrol.2008 [citado 12 abr 2016]; 4(2):80-89.Disponible en: http://www.nature.com/nrneph/journal/v4/n2/pdf/ncpneph0680.pdf
De Gowin EL, De Gowin R. Razonamiento diagnóstico. En: Síntomas y signos, datos de laboratorio, claves diagnósticas. Examen y diagnóstico clínicos. 2aed. México: La Prensa Mexicana; 1981.p.1-12
Díaz Novás J, Gallego Machado B, León González A. El diagnóstico médico: bases y procedimientos. Rev Cubana Med Gen Integr. 2006 [citado 3 abr 2016];22(1). Disponible en: http://bvs.sld.cu/revistas/mgi/vol22_1_06/mgi07106.htm