Monti FC, Caruso TA, Garay I, Kurpis M, Ruiz LA

Language: Spanish
References: 10
Page: 25-28
PDF size: 359.66 Kb.

ABSTRACT

Extramammary Paget disease (EMPD) is a rare intraepithelial adenocarcinoma that involves the skin with abundant apocrine glands, such as that of the vulva, perianal region, scrotum, penis and, less often, the axillary region. There are several theories regarding its pathogenesis; both the primary and secondary forms are accepted, the latter associated with internal malignancy. It presents clinically as a unique erythematous, scaly and eczematous plaque with a chronic evolution. For the diagnosis, both histopathology and immunohistochemical analyses are essential; this allows differentiation from other diseases of similar clinical presentation. The treatment of choice is surgery, although other alternatives have been described in patients who cannot tolerate the procedure. We report the case of a 62-year-old woman with a unilateral, axillary location of the disease which was rapidly evolving, without internal neoplasm; she underwent conventional surgery, with good results.

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