2017, Number 2
Presentation of a patient with prostate neuroendocrine adenocarcinoma
Language: Spanish
References: 9
Page: 613-619
PDF size: 381.54 Kb.
ABSTRACT
Prostate cancer commonly affects men after age 50; the evolution is slow, with histological variety of adenocarcinoma present in approximately 95%. It is not frequent to find histological differentiations of neuroendocrine type. A 29-year-old man from Banes was presented with perineal pain and discomfort during the sexual intercourse. The patient was assisted at Urology Consultation of the Lenin Hospital in Holguín where he was treated as a prostatic inflammatory process and antimicrobial and anti-inflammatory drugs were used. Other studies were not obtained and the prostate specific antigen reported high values; rectal examination revealed changes in consistency, a prostate biopsy was suggested, revealing a neuroendocrine adenocarcinoma of the prostate. When consulting the literature, specific therapeutic protocols were not available for these cases, but generally etoposide and cisplatin were used. The evolutions was torpid and rapid the appearance of bone, hepatic, mediastinal and ascites metastases as well as respiratory distress until the patient´s death, at 19 months the diagnosis was defined.REFERENCES
Arenas Reyes NJ, Manuel Moreno LA, Carrillo Rodríguez AP, Fonseca Buitrago CL, Daza Almendrales FP. Diferenciación neuroendocrina en cáncer de próstata. Revisión de la literatura. Rev Urol Colombiana. 2014[citado 26 mar 2017]; 23(1):39-43. Disponible en: http://www.redalyc.org/html/1491/149131193008/
Wang HT, Yao YH, Li BG, Tang Y, Chang JW, Zhang J. Neuroendocrine Prostate Cancer (NEPC) Progressing From Conventional Prostatic Adenocarcinoma: Factors Associated With Time to Development of NEPC and Survival From NEPC Diagnosis—A Systematic Review and Pooled Analysis. J Clin Oncol. 2014[citado 27 mar 2017]; 32(30): 3383-3390. Disponible en: http://ascopubs.org/doi/abs/10.1200/jco.2013.54.3553
Martínez Cornelio A, González Pérez J, Tabares García FJ, Ramos Salgado F, Alvarado Cabrero I, Hernández Toriz N. Bloqueo androgénico total en el manejo del cáncer de próstata neuroendocrino. Cir Ciruj. 2009[citado 26 mar 2017]; 77(4):293-299. Disponible en: http://www.redalyc.org/articulo.oa?id=66211210007