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ISSN 2992-779X (Electronic)
ISSN 2007-6452 (Print)

2017, Number 2

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Investigación en Discapacidad 2017; 6 (2)

Bacterial microorganisms associated with bloodstream infections in patients with burns at a reference center in Mexico City

Colín-Castro C, Chávez-Heres T, Magańa JJ, Franco-Cendejas R

Language: Spanish
References: 21
Page: 50-56
PDF size: 191.33 Kb.


ABSTRACT

Burn injuries cause an alteration in the skin barrier for infections, which allows the entry of microorganisms. Depending on the burn type, the prognosis may vary; however, the most important cause of morbidity and mortality in this type of patients are nosocomial infections, and a very serious one is the bloodstream. In this study we described the microorganisms that cause bloodstream infections in patients with burns in a period of three years. We included patients with burns treated from January 2013 to December 2015. The microorganisms causing the infection and their susceptibility profiles were identified. Demographic, clinical and outcome variables were compared with patients who did not present this infection. Thirty-two patients (7.7%) developed bloodstream infection and we identified 65 ethiological agents. Interestingly, P. aeruginosa was the most frequently identified microorganism, observing multidrug resistance in its susceptibility profile. This complication was observed in patients with a higher percentage of body surface area and was associated with an increase in hospital stay.


REFERENCES

  1. Church D, Elsayed S, Reid O, Winston B, Lindsay R. Burn wound infections. Clin Microbiol Rev. 2006; 19 (2): 403-434.

  2. Branski LK, Al-Mousawi A, Rivero H, Jeschke MG, Sanford AP, Herndon DN. Emerging infections in burns. Surg Infect (Larchmt). 2009; 10 (5): 389-397.

  3. Geyik MF, Aldemir M, Hosoglu S, Tacyildiz HI. Epidemiology of burn unit infections in children. Am J Infect Control. 2003; 31 (6): 342-346.

  4. Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 2003; 348 (16): 1546-1554.

  5. Vincent JL, Bihari DJ, Suter PM, Bruining HA, White J, Nicolas-Chanoin MH et al. The prevalence of nosocomial infection in intensive care units in Europe. Results of the European Prevalence of Infection in Intensive Care (EPIC) Study. EPIC International Advisory Committee. JAMA. 1995; 274 (8): 639-644.

  6. Richards MJ, Edwards JR, Culver DH, Gaynes RP. Nosocomial infections in combined medical-surgical intensive care units in the United States. Infect Control Hosp Epidemiol. 2000; 21 (8): 510-515.

  7. Pittet D, Tarara D, Wenzel RP. Nosocomial bloodstream infection in critically ill patients. Excess length of stay, extra costs, and attributable mortality. JAMA. 1994; 271 (20): 1598-1601.

  8. Rennie RP, Jones RN, Mutnick AH; SENTRY Program Study Group (North America). Occurrence and antimicrobial susceptibility patterns of pathogens isolated from skin and soft tissue infections: report from the SENTRY Antimicrobial Surveillance Program (United States and Canada, 2000). Diagn Microbiol Infect Dis. 2003; 45 (4): 287-293.

  9. CLSI.

  10. Kumar A, Ellis P, Arabi Y, Roberts D, Light B, Parrillo JE et al. Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock. Chest. 2009; 136 (5): 1237-1248.

  11. Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006; 34 (6): 1589-1596.

  12. Revista Digital Universitaria [revista en Internet]. 2012; 13 (9). ISSN: 1067-6079.

  13. Alberti C, Brun-Buisson C, Burchardi H, Martin C, Goodman S, Artigas A et al. Epidemiology of sepsis and infection in ICU patients from an international multicentre cohort study. Intensive Care Med. 2002; 28 (2): 108-121.

  14. Brusselaers N, Monstrey S, Snoeij T, Vandijck D, Lizy C, Hoste E et al. Morbidity and mortality of bloodstream infections in patients with severe burn injury. Am J Crit Care. 2010; 19 (6): e81-e87.

  15. Lee HG, Jang J, Choi JE, Chung DC, Han JW, Woo H et al. Blood stream infections in patients in the burn intensive care unit. Infect Chemother. 2013; 45 (2): 194-201.

  16. Chong SJ, Ahmed S, Tay JM, Song C, Tan TT. 5 year analysis of bacteriology culture in a tropical burns ICU. Burns. 2011; 37 (8): 1349-1353.

  17. Croft LD, Liquori M, Ladd J, Day H, Pineles L, Lamos E et al. The effect of contact precautions on frequency of hospital adverse events. Infect Control Hosp Epidemiol. 2015; 36 (11): 1268-1274.

  18. MacDougall C, Polk RE. Antimicrobial stewardship programs in health care systems. Clin Microbiol Rev. 2005; 18 (4): 638-656.

  19. Bahemia IA, Muganza A, Moore R, Sahid F, Menezes CN. Microbiology and antibiotic resistance in severe burns patients: A 5 year review in an adult burns unit. Burns. 2015; 41 (7): 1536-1542.

  20. King MD, Humphrey BJ, Wang YF, Kourbatova EV, Ray SM, Blumberg HM. Emergence of community-acquired methicillin-resistant Staphylococcus aureus USA 300 clone as the predominant cause of skin and soft-tissue infections. Ann Intern Med. 2006; 144 (5): 309-317.

  21. Renau-Escrig AI, Salavert M, Vivó C, Cantón E, Pérez Del Caz MD, Pemán J. Candidemia in major burns patients. Mycoses. 2016; 59 (6): 391-398.




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