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2016, Number 4

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Rev Mex Anest 2016; 39 (4)

Anesthetic induction with ketofol for burnt patients

Vázquez-Barreto M, Rivera-Ordoñez A, Salvador-Martínez R

Language: Spanish
References: 19
Page: 274-277
PDF size: 212.07 Kb.


ABSTRACT

Objective: Evaluate hemodynamic changes in burned patient’s during anesthetic induction using ketofol. Material and methods: A comparative study was conducted with a random selection forming two groups: propofol and ketofol. Monitoring vital signs in several minutes after induction. Results: 30 patients were included in each group. During induction of anesthesia with propofol patients had decreased 50% BIS while the group ketofol the decline was gradual maintaining spontaneous ventilation for one minute; in terms of hemodynamics in both groups was no difference in heart rate and peripheral arterial oxygen saturation pre and post induction. There was significant difference in values of mean arterial pressure after induction, a decrease of 30% in the propofol group and 10% in the group ketofol. T test was performed for independent samples obtained values of p = 0.004 at 5 minutes after induction, p = 0.08 at 10 minutes, p = 0.009 at 15 minutes. Conclusions: The combination of ketamine with propofol for induction of burn patient keeps the patient’s hemodynamic status.


REFERENCES

  1. Moctezuma-Paz LE, Páez-Franco I, Jiménez-González S, Miguel-Jaimes KD, Foncerrada-Ortega G, Sánchez-Flores AY et al. Epidemiología de las quemaduras en México. Rev Esp Méd Quir. 2015;20:78-82. Disponible en: http://www.nietoeditores.com.mx/nieto/EMQ/2015/ene-mar/art.revision_epidemiologia.pdf

  2. Gasca-Plancarte JD. Anestesia en el paciente quemado. Rev Mex Anest. 2013;36:S327-S330. Disponible en: http://www.medigraphic.com/pdfs/rma/cma-2013/cmas131ca.pdf

  3. Peña-Pérez CA, Carrillo-Esper R. Evaluación y manejo perioperatorio del paciente quemado. Rev Mex Anest. 2012;35:S207-S211. Disponible en: http://www.medigraphic.com/pdfs/rma/cma-2012/cmas121f5.pdf.

  4. Jandziol A, Hayes M. The cardiovascular response to burn injury. Currrent Anesthesia & Critical Care. 2008;19:269-274.

  5. Alarcón-Almanza JM, Castro-Ortega J, Moyao-García D, Ramírez-Mora JC. Modificación de los parámetros hemodinámicos y BIS durante la inducción con propofol vs propofol-ketamina en pacientes pediátricos. Rev Mex Anest. 2015;38:239-244.

  6. Rivera-Flores J, Campos-Villegas AF, Vázquez-Torres J, Zárate-Vázquez O, Chavira-Romero M. Manejo peri anestésico del paciente con quemaduras. Rev Mex Anest. 2004;27:57-65. Disponible en: http://www.medigraphic.com/pdfs/rma/cma-2004/cma041h.pdf

  7. Licea-Martínez JC. Elección de la técnica anestésica del paciente quemado. Rev Mex Anest. 2014;37:S232-S234. Disponible en: http://www.medigraphic.com/pdfs/rma/cma-2014/cmas141bj.pdf

  8. Niño de Mejía MC, Chaves A, Salazar CJ. Cambios hemodinámicos durante la inducción anestésica con tiopental versus propofol en pacientes asa I y II. Rev Colomb Anestesiol [Internet]. 2007 [citado 17 de mayo de 2016];35):53-58. Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S012033472007000100007&lng=en

  9. Daabiss M, Elsherbiny M, Alotibi R. Assessment of different concentration of Ketofol in procedural operation. BJMP. 2009;2:27-31.

  10. Hesham A, Rania S, Hesham H, Ahmed O. Comparative study between propofol, ketamine and their combination (ketofol) as an induction agent. Egyptian Journal of Anaesthesia. 2011;27:145-150. Available in: www.elsevier.com/locate/egja

  11. Gallo de Moraes A, Racedo Africano CJ, Hoskote SS, Reddy DR, Tedja R, Thakur L, et al. Ketamine and propofol combination (“ketofol”) for endotracheal intubations in critically ill patients: a case series. Am J Case Rep. 2015;16:81-86. Available in: http://www.amjcaserep.com/abstract/index/idArt/892424

  12. Hosseinzadeh H, Eidy M, Golzari SE, Vasebi M. Hemodynamic Stability during Induction of Anesthesia in ElderlyPatients: propofol + ketamine versus propofol + etomidate. J Cardiovasc Thorac Res. 2013;5:51-54.

  13. Canpolat DG, Esmaoglu A, Tosun Z, Akn A, Boyaci A, Coruh A. Ketamine-propofol vs ketamine-dexmedetomidine combinations in pediatric patients undergoing burn dressing changes. J Burn Care Res. 2012;33:718-722.

  14. Yagmurdur H, Aksoy M, Arslan M, Baltaci B. The effects of propofol and ketamine on gut mucosal epithelial apoptosis in rats after burn injury. Eur J Anaesthesiol. 2007;24:46-52.

  15. Riccobono M. Paciente quemado y TIVA. Rev Mex Anest. 2014;37:S230-S231. Disponible en: http://www.medigraphic.com/pdfs/rma/cma-2014/cmas141bi.pdf.

  16. Juárez F, Villatoro JA, López EK. Apuntes de estadística inferencial. México, D.F.: Instituto Nacional de Psiquiatría Ramón de la Fuente; 2002.

  17. Aguayo-Canela M. Cómo hacer una regresión logística con SPSS© “paso a paso”. DocuWeb fabis.org. Fundación Andaluza Beturia para la Investigación en Salud. 2007.

  18. McGuinness SK, Wasiak J, Cleland H, Symons J, Hogan L, Hucker T, et al. A systematic review of ketamine as an analgesic agent in adult burn injuries. Pain Med. 2011;12:1551-1558.

  19. Lawton G, Dheansa B. The management of major burns –a surgical perspective. Current Anesthesia & Critical Care. 2008;19:275-281.




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