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Academia Mexicana de Neurología, A.C.

2016, Number 4

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Rev Mex Neuroci 2016; 17 (4)

Semiology and evolution of febrile crisis at the Hospital Pediatrico Universitario Centro Habana

Portuondo BE

Language: Spanish
References: 33
Page: 54-66
PDF size: 333.99 Kb.


ABSTRACT

Introduction: Febrile seizures are the most common cause of acute symptomatic seizures in children.
Objective: To describe the semiology, recurrence rate, risk factors and evolution to epilepsy in a group of patients suffering from febrile crisis.
Method: An observational, prospective, descriptive study was conducted on patients suffering from febrile crisis between January 2005 and December 2013. Data were collected from medical records of the neurology clinic as well as admission files. Personal and family history, type of epileptic crisis and risk factors were considered. Epileptic crisis were classified as simple or complex.
Results: A total of 313 patients (185 female / 128 male), 68 (21.7%) had the first episode before the age of 12 months and 245 (78.3%) after this age. In all, 85.9% were considered as simple crisis (17.5% recurrent) and 14.1% complex. The family history of febrile crisis (31.6%) and the first episode before the age of one year (21.7%) were the most common risk factors associated with recurrence. The classical risk factors to develop epilepsy were identified in 16%, and the family history of epilepsy (15.6%) was the most common. In all, 19 patients evolved to epileptic syndromes and 5 were diagnosed with Dravet syndrome. Prophylactic treatment was used on 45 patients (10 transitory and 5 permanently) with oral diazepam, phenobarbital or valproic acid. A total of 17.5% of patients with simple febrile crisis had 3 more seizures and none after 6 years of age.
Conclusions: Febrile crisis have a good prognosis at short or long term. This condition are age-dependent and are usually simple. Continuous treatment can be useful only to prevent recurrences but not epilepsy.


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