Diosdado VF, González-Vega D, Moles-Cervantes LP, Morilla GA

Language: English/Spanish
References: 19
Page: 147-152
PDF size: 149.17 Kb.

ABSTRACT

In order to investigate a possible association between porcine reproductive and respiratory syndrome virus (PRRSV) and other viral and bacterial pathogenic agents found in swine, a serological model was followed. For this study, 3600, 4 to 6 month-old finishers were bled and tested for antibodies against various infectious agents. The specific antibodies against PRRSV, Aujeszky’s disease virus (ADV), transmissible gastroenteritis virus (TGEV), porcine respiratory coronavirus (PRCV) and Mycoplasma hyopneumoniae (MH) were detected by ELISA tests. For the blue eye disease virus (BEDV) and porcine parvovirus ( PPV), a hemoagglutination inhibition test was used. The microagglutination test was employed to determine antibodies against 11 serovars of Leptospira interrogans, while for Salmonella spp and Actinobacillus pleuropneumoniae serotype 1 (AP) the slide agglutination test was used. Antibodies against swine influenza virus (SIV) were detected by double diffusion test. The association between PRRSV and other microorganisms was evaluated by calculating the odds ratio (OR) and 95% confidence intervals (CI). In finishers, association was found between PRRSV and SIV (OR = 5.8, CI 95% 2.38, 14.55), PRCV (OR = 9.0, CI 95% 1.22, 82.53), and BEDV (OR = 2.95, CI 95% 1.16, 7.50). In 1 000 sows, association between PRRSV and SIV was found (OR = 3.54, CI 95% 1.29, 10.20), BEDV (OR =1.86, CI 95% 1.16, 3.00) and ADV (OR = 2.28, CI 95% 1.64, 3.18 ). No association between PRRSV infection and infection with TGEV, Salmonella spp, MH, AP or any of the leptospiral serovars was found.

REFERENCES

1. Diosdado VF, Socci EG, Morilla GA. Frecuencia de granjas infectadas con el virus del síndrome disgenésico y respiratorio del cerdo (PRRS) en México. Memorias de la XXXIII Reunión Nacional de Investigación Pecuaria; 1997 noviembre 3-8; Veracruz (Veracruz). México (DF), INIFAP, 1997:375.

2. Drew TW. A review of evidence for immunosuppression due to porcine reproductive and respiratory syndrome virus. Vet Res 2000;31:27-39

3. Albina E, Carrat C, Charley B. Interferon-alpha response to swine arterivirus (PoAV), the porcine reproductive and respiratory syndrome virus. J Interferon Cytokine Res 1998;18:485-490.

4. Thanawongnuwech R, Brown GB, Halbur PG, Roth JA, Royer RL, Thacker BJ. Pathogenesis of porcine reproductive and respiratory syndrome virus-induced increase in susceptibility to Streptcoccus suis infection. Vet Pathol 2000;37:143-152.

5. Kay RM, Done SH, Paton DJ. Effect of sequential porcine reproductive and respiratory syndrome and swine influenza on the growth and performance of finishers. Vet Rec 1994;135:199-204.

6. Van Reeth K, Nauwynck H, Pensaert M. Dual infections of feeder pigs with porcine reproductive and respiratory syndrome followed by porcine respiratory coronavirus or swine influenza virus: a clinical and virological study. Vet Microbiol 1996;48:325-335.

7. Pol JM, van Leengoed LA, Stockhofe N, Kok G, Wensvoort G. Dual infections of PRRSV/influenza or PRRSV/Actinobacillus pleuropneumoniae in the respiratory tract. Vet Microbiol 1997;55:259-264.

8. Groschup MH, Brun A, Haas B. Serological studies on the potential synergism of porcine reproductive and respiratory syndrome virus and influenza-, corona- and paramyxoviruses in the induction of respiratory symptoms in swine. J Vet Med B 1993;40:681-689.

9. Thacker EL, Halbur PG, Ross RF, Thanawongnuwech R, Thacker BJ. Mycoplasma hyopneumoniae potentiation of porcine reproductive and respiratory syndrome virus-induced pneumonia. J Clin Microbiol 1999;37:620-627.

10. Van Alstine WG, Stevenson GW, Kanitz CL. Porcine reproductive and respiratory syndrome virus does not exacerbate Mycoplasma hyopneumoniae infection in young pigs. Vet Microbiol 1996;49:297-303.

11. Stevenson GW, Van Alstine WG, Kanitz CL, Keffaber KK. Endemic porcine reproductive and respiratory syndrome virus infection in nursery pigs in two swine herds without current reproductive failure. J Vet Diagn Invest 1993;5:432-434.

12. Depner KR, Lange E, Pontrakulpipat S, Fichtner D. Does porcine reproductive and respiratory syndrome virus potentiate classical swine fever virus infection in weaner pigs? Zentralbl Veterinarmed [B] 1999;46:485-491.

13. Wesley RD, Mengeling WL, Lager KM. Prior infection of nursery-age pigs with porcine reproductive and respiratory syndrome virus does not affect the outcome of transmissible gastroenteritis virus challenge. J Vet Diagn Invest 1998;10:221-228.

14. Diosdado VF, Córdova LD, Socci EG, González VD, Morilla GA. Sinergismo potencial entre el virus de la Enfermedad de Aujeszky, Mycoplasma hyopneumoniae y Actinobacillus pleuropneumoniae en cerdos de engorda. Téc Pecu Méx 1999;37:23-30.

15. Thrusfield M. Veterinary Epidemiology 2nd ed. United Kingdom, Blackwell Science Ltd;1995.

16. Ontiveros CL, Camacho MJ, Alvarez CJ. Correlación entre la serotipificación de Actinobacillus pleuropneu-moniae y su aislamiento en cerdos de rastro. Téc Pecu Méx 1995;33:1-7

17. Done SH, Paton DJ. Porcine reproductive and respiratory syndrome: clinical disease, pathology and immunosuppression. Vet Rec 1995;136:32-35.

18. Bolin CA, Cassells JA, Hill HT, Frantz JC, Nielsen JN. Reproductive failure associated with Leptospira interrogans serovar bratislava infection of swine. J Vet Diagn Invest 1991;3:152-154.

19. Vezina SA, Loemba H, Fournier M, Dea S, Archambault D. Antibody-production and blastogenic response in pigs experimentally infected with porcine reproductive and respiratory syndrome virus. Can J Vet Res 1996;60:94-99.