2002, Number 5
<< Back Next >>
Med Crit 2002; 16 (5)
Scale of multiple organ failure dysfunction: Correlation with a modified scale
Huerta TJ, Casas TE, Cañada LM
Language: Spanish
References: 17
Page: 159-164
PDF size: 71.44 Kb.
ABSTRACT
Objective: To observe the correlation between the mea-surements of the punctuation of multiple organic dys-functions in the traditional form and the form recently modified.
Design: Observational prospective study.
Setting: A multidisciplinary critical care unit.
Patients: Eleven patients with mechanical ventilation support in more than 48 hours.
Interventions: None.
Measurements and main results: Lactic acid in blood was measured (2.3 ± 1.7) and APACHE II calculated (25 ± 12 points), MODS
AL (9 ± 5 points) and MODS
FAP (8.9 ± 5 points). The cardiovascular component with MODS
AL was of 0.9 ± 1.4 points and for the MODS
FAP of 0.8 ± 0.4 points. The correlation coefficient between MODS
AL and MODS
FAP was significant (r = 0.97; r
2 = 0.94; IC 95% 5.954-11.864 and 5.964-12.036 respectively; p = 0.97). For the cardiovascular component the correlation between the two forms to apply MODS was; r = 0.33 and
r
2 = 0.11; p = 0.84. Important differences were observed in the measured punctuation and the capacity to discri-minate cardiovascular failure when applying both MODS
in patients with chronic cardiovascular pathology and complex arrhythmias.
Conclusion: The correlation coefficient when calculating the punctuation of multiple organic dysfunctions with the original form and the form recently modified gives similar results. Nevertheless, in the patients with myocardial damage and complex arrhythmias the original MODS can underestimate the presence of cardiovascular failure.
REFERENCES
Knaus WA, Zimermman JE, Wagner DP et al. APACHE, acute and chronic health evaluation: A physiologically based classification system. Crit Care Med 1981;9:591-597.
Knaus WA, Draper EA, Wagner DP et al. APACHE II: A severity of disease classification system. Crit Care Med 1985;13:818-829.
Knaus WA, Wagner DP, Draper EA et al. The APACHE III prognostic system: Risk prediction of hospital mortality in critically ill hospitalized adults. Chest 1991;100:1619-1636.
LeGall JR, Loirat P, Alperovitch A et al. A simplified acute physiology score for ICU patients. Crit Care Med 1984;12: 975-977.
LeGall JR, Lemeshow S, Saulnier F. A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study. JAMA 1993;270:2957-2963.
Lemeshow S, Baue EA. Multiple, progressive or sequential system failure: A syndrome of the 1970s. Arch Surg 1975;110:779-781.
Lemeshow S, Teres D, Klar J et al. Mortality probability models (MPM II) based on an international cohort of intensive care unit patients. JAMA 1993;270:2478-2486.
Skillman JJ, Bushnell LS, Goldman H et al. Respiratory failure, hypotension, sepsis and jaundice: A clinical syndrome associated with letal hemorrhage and acute stress ulceration in the stomach. Am J Surg 1969;117:523-530.
Tilney NL, Bailey GL, Morgan AP. Sequential system failure after rupture of abdominal aortic aneurysms: An unsolved problem in postoperative care. Ann Surg 1973;178: 117-122.
Goris RJA, te Boekhorst TPA, Nuytinck JKS et al. Multiple-organ failure: Generalized autodestructive inflammation? Arch Surg 1985;120:1109-1115.
Tran DD, Groeneveld ABJ, van der Meulen J et al. Age, chronic disease, sepsis, organ system failure, and mortality in a medical intensive care unit. Crit Care Med 1990;18: 474-479.
Bone RC, Balk RA, Cerra FB et al. ACCP/SCCM Consensus Conference: Definitions for sepsis and organ failure guidelines for the use of innovative therapies in sepsis. Chest 1992;101:1644-1655.
Marshall JC, Cook DJ, Christou N et al. Multiple organ dysfunction score: A reliable descriptor of a complex clinical outcome. Crit Care Med 1995;23:1638-1652.
Vincent JL, Moreno R, Tácala J et al. The sepsis-related organ failure assessment (SOFA) score to describe organ dysfunction/failure. Intensive Care Med 1996;22:707-710.
LeGall JR, Klar J, Lemeshow S et al. The logistic organ dysfunction system: A new way to assess organ dysfunction in the intensive care unit. JAMA 1996;276:802-810.
Bernard GR, Doig G, Hudson L et al. Quantification of organ dysfunction for clinical trials and clinical practice. Am Rev Resp Crit Care Med 1995;151:A323.
Cook R, Cook D, Tilley J et al. Multiple organ dysfunction: Baseline and serial component scores. Crit Care Med 2001;29:2046-2050.