2004, Number 3
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Rev Mex Anest 2004; 27 (3)
Levobupivacaine compared with ropivacaine for caudal blockade in pediatric patients
Pineda-Díaz MV, Hernández-Carrillo MA, Gerardo-De La Cruz S, Hernández-Cruz MJ, Hernández-Pérez AL
Pineda-Díaz MV, Hernández-Carrillo, Gerardo-De La Cruz S, Hernández-Cruz MJ, Hernández-Pérez AL
Language: Spanish
References: 28
Page: 134-139
PDF size: 103.04 Kb.
ABSTRACT
Background: Election of a local anesthetic depends on its clinical and pharmacological
features, as well as its toxicity. Since local anesthetics have not been thoroughly evaluated in children, we compared two long-acting local
anesthetics, levobupivacaine and ropivacaine.
Material and methods: A randomized
clinical trial was carried out in 40 children, ages 1 to 7, ASA I-II, scheduled for 90-minute surgery in the lower abdomen, perineum or lower limbs under caudal
blockade. Pre-anesthetic medication was 0.4 mg/kg midazolam through the nose, 30 minutes before entering the OR. Type II monitoring. Patients were divided into two groups: Group I (n = 20) received 0.25% levobupivacaine and Group II (n = 20),0.25% ropivacaine, both as a single, 4 mg/kg and 1.6 ml/kg volume dose. Study variables: latency time, duration of action, residual motor block, vital signs, and side effects. Transanesthetic sedation with 1.5% sevorane and 100% oxygen were given.
Results: Group I: latency, 10 minutes; sensory block, 4.5 hours; diffusion,T5. Group II: latency, 14 minutes; sensory block, 4 hours; diffusion, T6. Residual motor block showed significant differences. A patient in Group I suffered moderate
transient hypotension.
Conclusions: Caudal anesthesia with both drugs proved satisfactory; hypotension is still the most frequent complication.
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