medigraphic.com
ISSN 2070-8718 (Print)

2014, Number 2

<< Back Next >>

Rev Cub Gen 2014; 8 (2)

Attitudes about depression and genetic studies in a sample of Cuban population

Monzón BG, Marcheco TB, Fuentes SLE, Mors O

Language: Spanish
References: 16
Page: 15-22
PDF size: 446.89 Kb.


ABSTRACT

Genetic research involves ethical, social, legal and medical issues, meanwhile psychiatric genetic knowledge adds more controversial issues. Ethical principles have been proposed as a guide in this field, but the optimal utilization of genetic testing has also been recognized to depend on both knowledge and attitudes of potential consumers and providers. To explore knowledge and attitudes about depression and psychiatric genetic testing, we surveyed 29 patients and relatives from a family with a psychiatric diagnosis of bipolar disorder, 181 medical students and 19 psychiatry specialists. A questionnaire was developed specifically for this study on the background of literature concerning ethical, legal, and social issues raised by psychiatric genetics and existing research on attitudes toward psychiatric genetics. It contains 100 items. Information was processed using the STATISTI CA 6,0 software. Most of the respondents correlated the onset of depression with a previous traumatic episode, General attitudes toward access to psychiatric genetic testing and information revealed substantial support for bioethical principles of autonomy and privacy, however, many respondents accepted that some tests may be considered obligatory. The contradictions and differences in attitudes among possible future users and providers of psychiatric genetic testing and counseling indicate ambivalence, insecurity, and perceived lack of knowledge in relation to psychiatric genetics, wich appointed to the need of developping educational strategies directed to the population and the medical care professionals.


REFERENCES

  1. Belloch A. Manual de Psicopatología, Volumen II, Trastornos Depresivos. McGraw -Hill/Interamericana de España 2009; 233-271.

  2. First Michael B. Manual diagnóstico y estadístico de los trastornos mentales. 4ta ed. Editorial MASSON; 2009.

  3. Cardelle F, Lorenzo T Manual de Residente de Psiquiatria. Depresión y Distimia. McGraw Hill/ Interamericana de España 2009; 285-293.

  4. Palomo T. Manual de Psiquiatría. Depresión unipolar y otras depresiones. EneLife Publicidad S.A. 2009; 322- 341.

  5. Wright A. Genes and Common Diseases. Cambridge University Press. Major psychiatric disorders in adult life. 2007; 454- 468.

  6. Mitjans M. Arias B. La genética de la depresión: ¿qué información aportan las nuevas aproximaciones metodológicas? Facultad de Biología. Universidad de Barcelona. Actas EspPsiquiatr 2012;40(2):70-83

  7. Hodge JG Jr. Ethical issues concerning genetic testing and screening in public health. Am J Med Genet Part C Semin Med Genet. 2004; 125C: 66–70.

  8. Gollust SE, Apse , Fuller BP, Miller PS, Biesecker BB. Community involvement in developing policies for genetic testing: Assessing the interests and experiences of individuals affected by genetic conditions. Am J Public Health. 2005; 95:35–41.

  9. Toiviainen H, Jallinoja P, Aro AR, Hemminki E. Medical and lay attitudes towards genetic screening and testing in Finland. Eur J Hum Genet. 2003; 11:565–572.

  10. Mett Marri Laegsgaard and ntentions Among Future Users and Providers. American Journal of Medical Genetics Part B (Neuropsychiatric Genetics). 2008; 147B:375–384.

  11. Jallinoja P. Genetics, negotiated ethics and the ambiguities of moral choices. Department of Sociology, University of Helsinki. Disponible en: http:// ethesis.helsinki.fi/julkaisut/val/sosio/vk/jallinoja/.2002.

  12. Bhardwaj M. Looking back, looking beyond: Revisiting the ethics of genome generation. J Biosci. 2006; 31:167–176.

  13. Laegsgaard MM1, Kristensen AS, Mors O. Potential consumers’ attitudes toward psychiatric genetic research and testing and factors influencing their intentions to test Genet Test Mol Biomarkers. 2009;13(1):57-65.

  14. Meiser B1, Kasparian NA, Mitchell PB, Strong K, Simpson JM, Tabassum L, et al. Schofield PR. Attitudes to genetic testing in families with multiple cases of bipolar disorder. Genet Test. 2008; Jun;12(2):233-43

  15. Henneman L, Vermeulen E, van El CG, Claassen L, Timmermans DR, Cornel MC. Public attitudes towards genetic testing revisited: comparing opinions between 2002 and 2010. Eur J Hum Genet. 2013;Aug;21(8):793-9

  16. Wilde A, Meiser B, Mitchell P. Community attitudes to genetic susceptibility-based mental health interventions for healthy people in a large national simple. Journal of Affective Disorders. 2011; November; 134, 1: 280-287.




2020     |     www.medigraphic.com