medigraphic.com
ISSN 1561-3119 (Electronic)

2016, Number 1

<< Back Next >>

Rev Cubana Pediatr 2016; 88 (1)

Risk factors related to the metabolic syndrome in obese children and adolescents

Corella TI, Miguel-Soca PE, Aguilera FPL, Suárez PE

Language: Spanish
References: 20
Page: 8-20
PDF size: 200.99 Kb.


ABSTRACT

Introduction: the metabolic syndrome in obese children and adolescents is a barely studied health problem in Holguin province.
Objective: to determine the risk factors related to the metabolic syndrome in obese children and adolescents.
Methods: the universe of study was 279 patients from which 93 (30%) obese children and adolescents of both sexes were included in the random sample; 43 with metabolic syndrome formed the case group and 50 made up the control group and they were all seen at the metabolic syndrome service of the University of Medical Sciences of Holguin province. The variance analysis or the Mann-Whitney U test was used. The binary logistic regression allowed identifying the risk factors. The level of significance was set at 0.05 in SPSS. The modified criteria of the National Cholesterol Education Program, according to the Cuban criteria for the diagnosis of metabolic syndrome, were applied (dependent variable).
Results: the risk factors for the metabolic syndrome were diastolic blood pressure (Odds Ratio= 1.10; 95% confidence interval= 1.04-1.17), blood hypertension (Odds Ratio= 15.97; 95% confidence interval= 4.86-52.38), triglyceride concentration (Odds Ratio= 7.82; 95% confidence interval= 2.83-21.63), hypertriglyceridemia (Odds Ratio= 11.40; 95% confidence interval= 3.83-33.92), low HDL cholesterol (Odds Ratio= 10.75; 95% confidence interval= 4.08-28.33), total cholesterol/HDL cholesterol index (Odds Ratio= 1.73; 95% confidence interval= 1.23-2.44) and LDLcholesterol/HDL-cholesterol index (Odds Ratio= 1.55; 95% confidence index= 1.12-2.16). The independent risk predictors were diastolic pressure (Odds Ratio= 1.16; 95% confidence interval= 1.06-1.26), the triglyceride concentration (Odds Ratio= 11.64; 95% confidence interval= 3.23-41.96) and the LDLcholesterol/HDL-cholesterol index (Odds Ratio= 2.04; 95% confidence interval= 1.26-3.30). Reactive C protein, microalbuminuria and diabetes mellitus were not risk factors.
Conclusions: the risk factors for the metabolic syndrome in children and adolescents were identified, which may be easily established at the primary health care.


REFERENCES

  1. Hirschler V, Calcagno ML, Aranda C, Maccallini G, Jadzinsky M. Síndrome metabólico en la infancia y su asociación con insulinorresistencia. Arch Argent Pediatr. 2006;104(6):486-91.

  2. Herrera OA. Síndrome metabólico en la infancia, un enfoque para la atención primaria. Rev Cubana Pediatr. 2015;87(1):82-91.

  3. Rosende A, Pellegrini C, Iglesias R. Obesity and metabolic syndrome in children and adolescents. Medicina (B Aires). 2013;73 (5):470-81.

  4. Miguel Soca PE, Niño Escofet S, Rodríguez López M, Almaguer Herrera A. Pesquisaje de síndrome metabólico en mujeres obesas. CCM [serie en Internet]. 2004 [citado 20 de mayo de 2015];8(4). Disponible en: http://www.cocmed.sld.cu/no84/n84ori5.htm

  5. Calderín Bouza RO, Prieto Valdés M, Cabrera Rode E. Síndrome de insulinorresistencia en niños y adolescentes. Rev Cubana Endocrinol [serie en Internet]. 2007 [citado 25 de mayo de 2015];18(2). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1561- 29532007000200007&lng=es

  6. Oquendo de la Cruz Y, Piñeiro Lamas R, Duarte MC, Guillen Dosal A. Síndrome metabólico en niños y adolescentes hipertensos obesos. Rev Cubana Pediatr. 2010;82(4):31-40.

  7. Alterio A, Alisi A, Liccardo D, Nobili V. Non-alcoholic fatty liver and metabolic syndrome in children: a vicious circle. Horm Res Paediatr. 2014;82(5):283-9.

  8. Colectivo de autores. Hipertensión arterial. Guía para la prevención, diagnóstico y tratamiento/Comisión Nacional Técnica Asesora del Programa de Hipertensión Arterial. La Habana: Editorial Ciencias Médicas; 2008.

  9. Rodríguez Domínguez L, Fernández-Britto JE, Díaz Sánchez ME, Ruiz Álvarez V, Hernández Hernández H, Herrera Gómez V, et al. Sobrepeso y dislipidemias en adolescentes. Rev Cubana Pediatr. 2014;86(4):433-44.

  10. Miguel Soca PE, Peña Pérez I, Niño Escofet S, Cruz Torres W, Niño Peña A, Ponce de León D. Ensayo clínico aleatorio: papel de la dieta y ejercicios físicos en mujeres con síndrome metabólico. Aten Primaria. 2012;44:387-93.

  11. Miguel Soca PE, Cruz Torres W, González Ferrer J, Cardona Cáceres X, Cruz Lage LA, Hernández Tamayo M. Efectos beneficiosos de cambios en la dieta y ejercicios físicos en mujeres obesas con síndrome metabólico. Panorama Cuba y Salud. 2009;4(3):29-36.

  12. Santiago Martínez Y, Miguel Soca PE, Ricardo Santiago A, Marrero Hidalgo MM, Peña Pérez I. Caracterización de niños y adolescentes obesos con síndrome metabólico. Rev Cubana Pediatr. 2012;84(1):11-21.

  13. Amador García M, Peña Escobar M, Hermelo Treche M, Martínez González Á. Obesidad. En: De la Torre Montejo E, Pelayo González-Posada EJ. Pediatría. Tomo I. La Habana: Editorial Ciencias Médicas; 2006. p. 264-73.

  14. Slaughter MH, Lohman TG, Boileau RA, Horsurll CA. Skinfolds equations for estimation of body fatness in children and youth. Hum Biol. 1988;60:709-23.

  15. Arnaiz P, Acevedo M, Díaz C, Bancalari R, Barja S, Aglony M, et al. Razón cintura estatura como predictor de riesgo cardiometabólico en niños y adolescentes. Rev Chil Cardiol. 2010;29(3):281-8.

  16. Balas-Nakash M, Villanueva-Quintana A, Tawil-Dayan S, Schiffman-Selechnik E, Suverza-Fernández A, Vadillo-Ortega F, et al. Estudio piloto para la identificación de indicadores antropométricos asociados a marcadores de riesgo de síndrome metabólico en escolares mexicanos. Bol Med Hosp Infant Mex. 2008;65(2):100-9.

  17. Lee MS, Wahlqvist ML, Yu HL, Pan WH. Hyperuricemia and metabolic syndrome in Taiwanese children. Asia Pac J Clin Nutr. 2007;16:594-600.

  18. Miguel Soca PE. El síndrome metabólico: un alto riesgo para individuos sedentarios. Acimed [serie en Internet]. 2009 [citado 22 de mayo de 2015];20(2). Disponible en: http://scielo.sld.cu/pdf/aci/v20n2/aci07809.pdf

  19. Dimitrijevic-Sreckovic V, Colak E, Djordjevic P, Gostiljac D, Sreckovic B, Popovic S, et al. Prothrombogenic factors and reduced antioxidative defense in children and adolescents with pre-metabolic and metabolic syndrome. Clin Chem Lab Med. 2007;45(9):1140-4.

  20. Chang Y, Yoo T, Ryu S, Huh BY. Abdominal obesity, systolic blood pressure, and microalbuminuria in normotensive and euglycemic Korean men. Int J Obes. 2006;30:800-4.




2020     |     www.medigraphic.com