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2015, Number 2

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Rev Med MD 2015; 6.7 (2)

Interstitial Lung Disease as extra-articular manifestation of Rheumatoid Arthritis in elderly: a case report

Orozco-Gascón CA, Díaz-Ramos JA, Leal-Mora D

Language: Spanish
References: 25
Page: 91-95
PDF size: 1028.01 Kb.


ABSTRACT

Rheumatoid Arthritis (RA) is a systemic disease characterized by symmetric polyarthritis. Its pathophysiology is essentially inflammatory and autoimmune. It affects 1% of the population and is potentially disabling. Half of the patients with RA have extra-articular manifestations (e.g. skin, eyes, cardiac and pulmonary conditions). Interstitial Lung Disease associated with RA (ILD-RA) is an early manifestation of AR, and their presence increases up to three times the risk of death. The presentation of ILD-RA ranges from subclinical inflammation to severe pulmonary fibrosis. Accurate diagnosis of the ILD-RA is hampered by the absence of symptoms in the early stages of the disease. High Resolution Computed Tomography (HR-CT) is a sensitive method for the assessment of pulmonary abnormalities in RA. Although ILD is a known complication of RA, details about the etiology and risk factors are poorly understood. The aim of this study was to present a case of ILD-RA and describe clinical manifestations in elderly. Information is beneficial for identifying patients at risk, and provides fundamental knowledge for the development of appropriate therapeutic strategies.


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