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2003, Number 4

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Rev Inst Nal Enf Resp Mex 2003; 16 (4)

Microchimerism and Human Diseases.

Bustos EML

Language: Spanish
References: 53
Page: 261-270
PDF size: 89.03 Kb.


ABSTRACT

Harboring of cells from another individual is referred to as chimerism, and microchimerism indicates low levels of non-host cells. Chronic graft-versus-host disease is a condition of human chimerism, that shares clinical similarities with some autoimmune diseases especially systemic sclerosis, primary biliary cirrhosis and Sjögren’s syndrome. This led to the hypothesis that microchimeric cells could be involved in the pathogenesis of autoimmune diseases. Persistence of fetal cells in women as well as maternal cells in their offspring have been reported, but contradictory results for most of the diseases investigated cause difficulty in drawing any conclusions about the role of microchimerism in the pathogenesis of autoimmune diseases.


REFERENCES

  1. Nelson JL. Microchimerism and the Pathogenesis of Systemic Sclerosis. Curr Opin Rheumatol 1998;10:564-571.

  2. Nelson JL. Microchimerism and the Causation of Scleroderma. Sacand J Rheumatol 1988;27:10-13.

  3. Hall JM, Lingenfelter P, Adams SL, Lasser D, Hansen JA, Bean MA. Detection of Maternal Cells in Human Umbilical Cord Blood Using Fluorescence in situ Hybridization. Blood 1995;867:2829-2832.

  4. Lo YMD, Lo ESF, Watson N, Noakes L, Sargent IL, Thilaganathan B, et al. Two-way Cell Traffic between Mother and Fetus. Biological and Clinical Implications. Blood 1996; 88:4390-4396.

  5. Lo Y, Lau T, Chan L, Leung T, Chang A. Quantitative Analysis of the Bi-directional Fetomaternal Transfer of Nucleated Cells and Plasma DNA. Clin Chem 2000; 46:1301-1309.

  6. Bianchi DW, Zickwolf GK, Weil GJ, Sylvester S, De Maria A. Male Fetal Progenitors Cells Persist in Maternal Blood for as Long as 27 Years post partum. Proc Natl Acad Sci 1996;93:705-705.

  7. Lo Y, Hjelm N, Thilagathan B. Transfer of Nucleated Maternal Cells into Fetal Circulation during the Second Trimester of Pregnancy. Br J Haematol 1998;100:605-618.

  8. Maloney S, Smith A, Furst D, Myerson D, Rupert K, Evans P, et al. Microchimerism of Maternal Origin Persists into Adult Life. J Clin Investig 1999;104:41-47.

  9. Bianchi D, Farina A, Weber W, Delli-Bovi L, De Riso M, Williams J, et al. Significant Fetal-maternal Hemorrhage after Termination of Pregnancy: Implications for Development of Fetal Cell Microchimerism. Am J Obstet Gynecol 2001;184:703-706.

  10. De Moor G, De Bock G, Noems I, De Bic S. A New Case of Human Chimerism Detected after Pregnancy: 46, XY Karyotype in the Lymphocytes of a Woman. Acta Clin Belg 1988;43:231-235.

  11. Campbell D, Lorber M, Sweeton J, Turcotte J, Niederhuber J, Beer A. Breast Feeding and Maternal-donor Renal Allografts. Transplantation 1984;37;340-344.

  12. Lee TH, Plagieroni T, Ohto H, Holland PV, Busch M. Survival of Donor Leukocyte Subpopulation in Immunocompetent Transfusion Recipients: Frequent Long-term Microchimerism in Severe Trauma Patients. Blood 1999;93:3127-3139.

  13. Graham-Brown R, Sarkany I. Scleroderma-like Changes due to Chronic Graft-versus-host Disease. Clin Exp Dermatol 1983;8:531-538.

  14. Janin-Mercier A, Devergie A, Van Cauwenberg D. Immunohistologic and Ultrastructural Study of the Sclerotic Skin in Chronic Graft-versus-host Disease. Br J Dermatol 1996;134:848-854.

  15. De Wit D, Van Mechelen M, Zanin C, Doutrelepont J, Velu T, Gerard C. Preferential Activation of Th-2 Cells in Chronic Graft-versus-host Disease. J Immunol 1993;150:361-366.

  16. Medsger T. Epidemiology of Systemic Sclerosis. Clin Dermatol 1994; 12:207-216.

  17. Nelson L, Furst D, Maloney S, Gooley T, Evans P, Smith A, et al. Microchimerism and HLA-compatible Relationship of Pregnancy in Scleroderma. Lancet 1998;351:559-562.

  18. Lambert N, Lo D, Erickson T, Tylee T, Guthrie K, Furst D, et al. Male Microchimerism in Healthy Women and Women with Scleroderma: Cells or Circulating DNA? A Quantitative Answer. Blood 2002;100:2845-2851.

  19. Artlett CM, Smith JB, Jiménez SA. Identification of Fetal DNA and Cells in Skin Lesions from Women with Systemic Sclerosis. N Engl J Med 1998;338:1186-1191.

  20. Artlett C, Cox L, Ramos R, Dennis T, Fortunato R, Hummers L, et al. Increased Microchimeric CD4+ T Lymphocytes in Peripheral Blood from Women with Systemic Sclerosis. Clin Immunol 2002;103:303-308.

  21. Launay D, Hebbar M, Hatron PY, Michon-Pasturel U, Queyrel V, Hachulla E, et al. Relationship between Parity and Clinical and Biological Features in Patients with Systemic Sclerosis. J Rheumatol 2001;28:509-513.

  22. Evans P, Lambert N, Maloney S, Furst D, Moore J, Nelson L. Long-term Fetal Microchimerism in Peripheral Blood Mononuclear Cell Subsets in Healthy Women and Women with Scleroderma. Blood 1999;93:2033-2037.

  23. Scaletti C, Vultaggio A, Bonifacio S, Emmi L, Torricelli F, Maggi E, et al. Th2-oriented Profile of Male Offspring T Cells Present in Women with Systemic Sclerosis and Reactive with Maternal Major Histocompatibility Complex Antigens. Arthritis Rheum 2002;46: 445-450.

  24. Hideyuki M, Hiromitsu N, Takayuki S. Microchimerism in Japanese Women Patients with Systemic Sclerosis. Lancet 1999;354:220.

  25. Selva-O’Callagham A, Mijares Boeckh-Behrens T, Balada E, Solans R, Simeón-Aznar C, Fonollosa V, et al. Lack of Evidence of Foetal Microchimerism in Female Spanish Patients with Systemic Sclerosis. Lupus 2003;12:15-20.

  26. Gannagé M, Amoura Z, Lantz O, Piette J, Caillat-Zucman S. Feto-Maternal Microchimerism in Connective Tissue Diseases. Eur J Immunol 2002;32:3405-3413.

  27. Johnson KL, Nelson JL, Furst DE, McSweeney PA, Roberts DJ, Zhen DK, et al. Fetal Cell Microchimerism in Tissue from Multiple Sites in Women with Systemic Sclerosis. Arthritis Rheum 2001;44:1848-1854.

  28. Lambert N, Evans P, Hashizumi T, Maloney S, Gooley T, Furst D, et al. Persistent Fetal Microchimerism in T Lymphocytes is Associated with HLA-DQA1*0501: Implications in Autoimmunity. J Immunol 2000;164: 5545-5548.

  29. Artlett CM, Cox LA, Jiménez SA. Detection of Cellular Microchimerism of Male or Female Origin in Systemic Sclerosis Patients by Polymerase Chain Reaction Analysis of HLA-Cw Antigens. Arth Rheum 2000; 43:1062-1067.

  30. Christner P, Artlett C, Conway R, Jiménez S. Increased Numbers of Microchimerism Cells of Fetal Origin are Associated with Dermal Fibrosis in Mice Following Injection of Vinyl Choride. Arthritis Rheum 2000; 43: 2598-2605.

  31. Czaja A. Chronic Graft-versus-host Disease and Primary Biliary Cirrhosis Sorting the Puzzle Pieces. Lab Invest 1994;70:589-592.

  32. Fanning P, Jonsson J, Clouston A, Edwards-Smith C, Balderson G, Macdonald G, et al. Detection of Male DNA in the Liver of Female Patients with Primary Biliary Cirrhosis. J Hepatol 2000;33:690-695.

  33. Corpechot C, Barbu V, Chazouilleres O, Poupon R. Fetal Microchimerism in Primary Biliary Cirrhosis. J Hepatol 2000;33:696-700.

  34. Invernizzi P, De Andreis C, Sirchia S, Battezzati P, Zuin M, Rossella F, et al. Blood Fetal Microchimerism in Primary Biliary Cirrhosis. Clin Exp Immunol 2000;122:418-422.

  35. Tanaka A, Lindor K, Gish R, Batts K, Shiratori Y, Omata M, et al. Fetal Microchimerism alone does not Contribute to the Induction of Primary Biliary Cirrhosis. Hepatology 1999;30:833-838.

  36. Schoniger-Hekele M, Muller C, Ackermann J, Drach J, Wrba F, Penner E, et al. Lack of Evidence for Involvement of Fetal Microchimerism in Pathogenesis of Primary Biliary Cirrhosis. Dig Dis Sci 2002;47:1909-1914.

  37. Meg C, Lockshin M. Pregnancy in Lupus. Curr Opin Rheumatol 1999; 11:348-351.

  38. Johnson K, McAli don T, Mulcahy E. Microchimerism in a Female Patient with Systemic Lupus Erythematosus. Arthritis Rheum 2001;44:2107-2111.

  39. Abbud M, Pavarino E, Alvarenga M, Fernandes I, Toledo R, Tajara E, et al. Systemic Lupus Erythematosus and Microchimerism in Autoimmunity. Transplantat Proc 2002;34:2951-2952.

  40. Mosca M, Curcio M, Lapi S, Valentini G, D’Angelo S, Rizzo G, et al. Correlation of Y Chromosome Microchimerism with Disease Activity in Patients with SLE: Analysis of Preliminary data. Ann Rheum Dis 2003; 62:651-654.

  41. Srivatsa B, Srivatsa S, Johnson K, Samura O, Lee S, Bianchi D. Microchimerism of Presumed Fetal Origin in Thyroid Specimens from Women: a Case Control Study. Lancet 2001;358:2034-2038.

  42. Ando T, Imaizumi M, Graves P, Unger P, Davies T. Intrathyroidal Fetal Microchimerism in Graves’ Disease. J Clin Endocrinol Metab 2002;87:3315-3320.

  43. Imaizumi M, Pritsker A, Unger P, Davies T. Intrathyroidal Fetal Microchimerism in Pregnancy and post- partum. Endocrinology 2002;143:247-253.

  44. Kuroki M, Okayama A, Nakamura S, Sasaki T, Murai K, Shiba R, et al. Detection of Maternal-fetal Microchimerism in the Inflammatory Lesions of Patients with Sjögren’s Syndrome. Ann Rheumatic Dis 2002; 61:1041-1046.

  45. Endo Y, Negishi I, Ishikawa O. Possible Contribution of Microchimerism to the Pathogenesis of Sjögren’s Syndrome. Rheumatology 2002;41:490-495.

  46. Aractingi S, Sibilia J, Meignin V, Launay D, Hachulla E, Le Danff C, et al. Presence of Microchimerism in Labial Salivary Glands in Systemic Sclerosis but not in Sjögren’s Syndrome. Arthritis Rheum 2002;46:1039-1043.

  47. Aractingi S, Berkane N, Bertheau P, Le Goué C, Dausset J, Uzan S. Fetal DNA in Skin of Polymorphic Eruptions of Pregnancy. Lancet 1998;352:1898-1901.

  48. Ansari A, Fett J, Carraway R, Mayne A, Onlamoon N, Sundstrom J. Autoimmune Mechanisms as the Basis for Human Peripartum Cardiomyopathy. Clin Rev Allergy Immunol 2002;233:301-324.

  49. Pollack M, Kikpatrick D, Kapoor N, Dupont B, O”ReillyR. Identification by HLA Typing of Intrauterine Derived Maternal T-cells in four Patients with Severe Combined Immuno-deficiency. N Engl J Med 1982; 307:662-666.

  50. Artlett C, Ramos R, Jiménez S, Patterson K, Miller F, Rider L. Chimeric Cells of Maternal Origin in Juvenile Idiopathic Inflammatory Myopathies. Lancet 2000;356: 2155-2156.

  51. Artlett C, Miller W, Rider L. Persistent Maternally Derived Peripheral Microchimerism is Associated with the Juvenile Idiopathic Inflammatory Myopathies. Rheumatology 2001;40:1279-1284.

  52. Reed A, Picornell Y, Harwood A, Kredich D. Chimerism in Children with Juvenile Dermatomyositis. Lancet 2000;356:2156-2157.

  53. Srivatsa B, Srivatsa S, Jhonson K, Bianchi D. Maternal Cell Microchimerism in Newborn Tissues. J Pediatr 2003;142:31-35.




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