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2003, Número 4

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Rev Inst Nal Enf Resp Mex 2003; 16 (4)


Repercusiones de un asesino (NK)

Rosas MLP, Abarca RE, Nava RH, Zamudio CP

Idioma: Español
Referencias bibliográficas: 27
Paginas: 257-260
Archivo PDF: 100.45 Kb.


RESUMEN

Las células NK constituyen parte del sistema inmune innato; morfológicamente son linfocitos grandes y presentan abundantes gránulos intracitoplásmicos. Al activarse las células NK se diferencian en células efectoras de corta vida, cuya función es identificar y contener a las células que presentan patrones moleculares que indiquen daño, ya sea por estrés, transformación maligna y/o infección a ciertos virus y a otros patógenos intracelulares. Además, modulan el crecimiento de células hematopoyéticas al producir una gran variedad de citocinas y quimiocinas. Investigaciones recientes permiten sugerir a las células NK como modelo bioenergético para el estudio de la diferenciación celular.


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