2016, Number 1
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Rev Mex Ing Biomed 2016; 37 (1)
Reference Equations for Impulse Oscillometric and Respiratory System Model Parameters in Anglo and Hispanic Children
Meraz EG, Nazeran H, Edalatpour R, Rodriguez C, Montano K, Aguilar C, Avila N, Vidaña JO, Portillo AL
Language: English
References: 37
Page: 49-61
PDF size: 960.49 Kb.
ABSTRACT
The Impulse Oscillometry System (IOS) has been recognized as a useful diagnostic tool. Previous research
by our group has shown that R5 (Resistance at 5 Hz), R5-R20 (frequency dependence of resistance), AX (the
“Goldman Triangle”) and the extended Resistor-Inductor-Capacitor (eRIC) model-derived parameter Cp (peripheral
Compliance) are reliable measures that track respiratory system function. Here we determined the predictive
equations from 112 asthmatic and non-asthmatic Anglo and Hispanic children data, that were previously classified
into four groups: Normal, PSAI (Probable Small Airway Impairment), SAI (Small Airway Impairment), and Asthma
by using regression analysis of IOS and eRIC model parameters as dependent variables regressed against age, height,
and weight. Height showed the greatest correlation with IOS and eRIC model parameters and provided the most
significant reference values for these measures in Anglo and Hispanic children. These values could serve as a useful
framework for diagnosis, early interventions, and treatment of respiratory diseases in this population.
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