Alcocer-Maldonado JL, Mora-Constantino J, Domínguez-Carrillo LG, Domínguez-Gasca LG

Language: Spanish
References: 13
Page: 255-258
PDF size: 218.02 Kb.

ABSTRACT

Background: Hemangioblastomas are benign neoplasias originated in the central nervous system; they constitute 2.5% of intracranial tumors. The majority of them are infratentorial, affecting the cerebellum (75%). Supratentorial lesions are rare, being the frontal the most common location in these cases. Meningeal involvement is infrequent. In 25% of the cases, these tumors are associated with von Hippel Lindau syndrome. Case report: Twenty-six-year-old woman with a 10-week-pregnancy. She presented with neurological symptoms characterized by cephalalgia, vomitus and papilledema that had been ongoing for three weeks. The cranial magnetic resonance scan showed a solitary solid-cystic lesion on the left occipital lobe. It was diagnosed as meningosarcoma and operated on. The pathological analysis showed a lesion composed of polygonal cells with clear cytoplasm, intracytoplasmic vacuoles and round or oval nucleus without cytologic atypia. These cells were accompanied by a rich vascular network of capillary type. The histopathologic diagnosis was supratentorial hemangioblastoma. Conclusions: The preoperative diagnosis of these neoplasms is difficult because the clinical suspicion is low in supratentorial location. Definitive diagnosis is made through histopathologic examination and immunohistochemical techniques. The importance of the possible association with von Hippel Lindau syndrome and its complications has prognostic relevance.

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