medigraphic.com
ISSN 2007-087X (Print)
Órgano Oficial de la Sociedad Mexicana de Ortopedia Pediátrica

2015, Number 1

<< Back

Rev Mex Ortop Ped 2015; 17 (1)

Diagnostic considerations in hemihypertrophy

Colmenares-Bonilla D

Language: Spanish
References: 37
Page: 39-44
PDF size: 149.07 Kb.


ABSTRACT

There is not a true incidence of hemihypertrophy, since slight deviations in limb lenght are considered normal. There are clinical reports of patients in search for medical care for limb length discrepancy. In some cases this discrepancy is visible since birth if it is enough to be seen. Hemihypertrophy is classified as not sindromatic when there is not vinculation with genetic síndromes; in syndromic hemihipertrophy, the definite diagnosis is a need, since very different prognostic diferences. The most common medical conditions associated with hamihypertrophy are neurofibromatosis and Proteus, Klippel-Trenaunay Weber and Beckwith-Wiedemann syndromes.


REFERENCES

  1. Kumar V, Abbas AK, Fausto N. Robbins y Cotran: patología estructural y funcional. 7a. ed. Madrid: Elsevier España, 2005. p. 1517.

  2. Hoyme HE, Seaver LH, Jones KL, Procopio F, Crooks W, Feingold M. Isolated hemihyperplasia (hemihypertrophy): report of a prospective multicenter study of the incidence of neoplasia and review. Am J Med Genet. 1998; 79(4): 274-278.

  3. Dempsey-Robertson M, Wilkes D, Stall A, Bush P. Incidence of abdominal tumors in syndromic and idiopathic hemihypertrophy/isolated hemihyperplasia. J Pediatr Orthop. 2012; 32 (3): 322-326.

  4. Clericuzio CL, Martin RA. Diagnostic criteria and tumor screening for individuals with isolated hemihyperplasia. Genet Med. 2009; 11 (3): 220-222.

  5. Pappas AM, Nehme AM .Leg length discrepancy associated with hypertrophy. Clin Orthop. 1979; 144: 198-211.

  6. Ballock RT, Wiesner G, Myers M, Thompson GH. Current concepts review – hemihypertrophy. concepts and controversies. J Bone Joint Surg (Am). 1997; 79-A: 1731-1738.

  7. Beals RK. Hemihypertrophy and Hemihypotrophy. Clin Orthop Relat Res. 1982; (166): 199-203.

  8. Kenneth JG, Brinker MR, Kousseff BG et al. Overgrowth management in Klippel-Trenaunay-Weber and Proteus Syndromes. J Ped Orthop; 1993; (13): 459-466.

  9. Amini Z, Babovic-Vuksanovic D, Lteif A. Bilateral pheochromocytomas in a child who had hemihypertrophy and alteration in the VHL gene. J Pediatr Endocrinol Metab. 2013; 26(3-4): 369-372.

  10. Weksberg R, Shuman C, Beckwith JB. Beckwith-Wiedemann syndrome. Eur J Hum Genet. 2010; 18(1): 8-14.

  11. Boxer LA, Smith DL. Wilms’ tumor prior to onset of hemihypertrophy. Am J Dis Child. 1970; 120: 564-565.

  12. Parker L, Kollin J, Vicario D, Nguyen T. Hemihypertrophy as possible sign of renal cell carcinoma. Urology. 1992; 40: 286-288.

  13. Mendoza RH, Valiente MD. Hemihipertrofia con indiferencia al dolor. Bol Med Hosp Infan Mex. 1997; 54(3): 141-146.

  14. Carney JA, Ho J, Kitsuda K, Young WF Jr, Stratakis CA. Massive neonatal adrenal enlargement due to cytomegaly, persistence of the transient cortex, and hyperplasia of the permanent cortex: findings in Cushing syndrome associated with hemihypertrophy. Am J Surg Pathol. 2012; 36(10): 1452-1463.

  15. Maniar S, Azzi K, Iraqi H, El Hassan Garbi M, Chraibi A, Gaouzi A. Idiopathic corporeal hemihypertrophy associated with hemihypertrichosis. Ann Endocrinol (Paris). 2011; 72(1): 48-52.

  16. Ringrose RE, Jabbour JT, Keele DK. Hemihypertrophy. Pediatrics. 1965; 36: 434.

  17. Bliek J, Maas S, Alders M, Merks J, Mannens M. Epigenotype, phenotype, and tumors in patients with isolated hemihyperplasia. J Pediatr. 2008; 153: 95-100.

  18. Friberg O. Clinical symptoms and biomechanics of lumbar spine and hip joint in leg length inequality. Spine. 1983; 8(6): 643-651.

  19. MacEwen GD, Case JL. Congenital hemihypertrophy. A review of 32 cases. Clin Orthop. 1967; 50: 147-150.

  20. Redondo P, Bastarrika G, Aguado L, Martínez-Cuesta A, Sierra A, Cabrera J, Alonso-Burgos A. Foot or hand malformations related to deep venous system anomalies of the lower limb in Klippel-Trénaunay syndrome. J Am Acad Dermatol. 2009; 61(4): 621-628.

  21. McGrory BJ, Amadio PC, Dobyns JH, Stickler GB, Unni KK. Anomalies of the fingers and toes associated with Klippel-Trenaunay syndrome. J Bone Joint Surg Am. 1991; 73: 1537-1546.

  22. Weber FP. Angioma formation in conection with hypertrophy of limbs and hemihypertrophy. Br J Dermatol. 1907; 19: 231-237.

  23. Feldman DS, Jordan C, Fonseca L. Orthopaedic manifestations of neurofibromatosis type 1. J Am Acad Orthop Surg. 2010; 18(6): 346-357.

  24. Shahgholi E, Mollaian M, Haghshenas Z, Honarmand M. Congenital rhabdomyosarcoma, central precocious puberty, hemihypertrophy and hypophosphatemic rickets associated with epidermal nevus syndrome. J Pediatr Endocrinol Metab. 2011; 24(11-12): 1063-1066.

  25. Crawford AH1, Schorry EK. Neurofibromatosis update. J Pediatr Orthop. 2006; 26(3): 413-423.

  26. Li Z, Shen J, Liang J. Thoracolumbar scoliosis in a patient with proteus syndrome: a case report and literature review. Medicine (Baltimore). 2015; 94(5): e360.

  27. Biesecker L. The challenges of Proteus syndrome: diagnosis and management. Eur J Hum Genet. 2006; 14(11): 1151-1157.

  28. Greene AK, Kieran M, Burrows PE, Mulliken JB, Kasser J, Fishman SJ. Wilms tumor screening is unnecessary in Klippel-Trenaunay syndrome. Pediatrics. 2004; 113(4): e326-e329.

  29. Klippel M, Trenaunay P. Du naevux variquex osteohypertrophique. Arch Gen Med. 1900; 185: 641-672.

  30. Gloviczki P, Hollier LH, Telander RL, Kaufman B, Bianco AJ, Stickler GB. Surgical implications of Klippel-Trenaunay syndrome. Ann Surg. 1983; 197: 353-362.

  31. Pardo de la Vega M, Prieto M, Galbe M, García A. Síndrome de Beckwith-Wierdeann: Factor de riesgo para el desarrollo de tumores. A propósito de un caso. Bol Pediatr. 2001; 41: 41-44

  32. Sotelo-Ávila C, González-Crussi F, Fowler JW. Complete and incomplete forms of Beckwith-Wiedemann syndrome: their oncogenic potential. J Pediatr. 1980; 96(1): 47-50.

  33. Porteus MH, Narkool P, Neuberg D, Guthrie K, Breslow N, Green DM et al. Characteristics and outcome of children with Beeckwith-Wiedemann Syndrome and Wilms Tumor: a report from the National Wilms Tumor Study Group. Journal of Clinical Oncology. 2000; 18: 2026-2031.

  34. Hamada Y, Takada K, Fukunaga S, Hioki K. Hepatoblastoma associated with Beckwith-Wiedemann syndrome and hemihypertrophy. Pediatr Surg Int. 2003; 19(1-2): 112-114.

  35. Galli-Tsinopoulou A, Emmanouilidou E, Karagianni P, Grigoriadou M, Kirkos J, Varlamis GS. A female infant with Silver Russell Syndrome, mesocardia and enlargement of the clitoris. Hormones (Athens). 2008; 7(1): 77-81.

  36. Prasad NR, Reddy PA, Karthik TS, Chakravarthy M, Ahmed F. A rare case of Silver-Russell syndrome associated with growth hormone deficiency and urogenital abnormalities. Indian J Endocrinol Metab. 2012; 16(Suppl 2): S307-S39.

  37. Maffulli N, Fixsen JA. Fibular hypoplasia with absent lateral rays of the foot. J Bone Joint Surg (Br). 1991; 73-B: 1002-1004.




2020     |     www.medigraphic.com