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2001, Number 2

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Rev Inst Nal Enf Resp Mex 2001; 14 (2)

Value diagnostic of the fine needle aspiration biopsy during mediastinoscopy.

Suárez SJP, Rico MGF, Madrazo LL, Sánchez JA

Language: Spanish
References: 16
Page: 85-89
PDF size: 147.37 Kb.


ABSTRACT

Objective: To investigate the value of fine needle aspiration biopsy (FNAB) during mediastinoscopy in neoplasic thorax disease diagnosis. Material and methods: Twenty patients were studied (12 men, 8 women). Average age was 56 years (range from 18 to 75) with suspected bronchogenic carcinoma with metastases in mediastinal nodes and with mediastinal tumor. FNAB was performed simultaneously with mediastinoscopy by inserting a fine needle into the tumor or into the cluster of lymphatic nodes, vacuuming via a 20 mL hypo syringe, and preparing a smear immediately, which was analyzed simultaneously but separately from biopsies of the same lesion. Results: Thirteen patients out of 20 (65%) underwent FNAB and node lymph biopsy. Exact pathologic correlation of both results occurred in 12 (92%), one false negative in 1 (8%) case. Seven out of 20 patients (35%) underwent FNAB and mediastinal tumor or central pulmonary neoplasm biopsy. In these cases, pathological correlation was 100%. Global correlation was 19 (95%) out of 20 patients with sensitivity of 95%, overall accuracy 95% and positive predictive value 95%. No complications arose related to the procedure. Conclusion: FNAB is highly accurate in diagnosis and regarding histopathological correlation. We therefore recommend its use without the need for biopsy in situations where the tumor, lymphatic node and vascular plans are not clearly visible, to avoid damage to the large vessels or to another mediastinal structure.


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