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2005, Number 3

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Acta Pediatr Mex 2005; 26 (3)

Importance of laboratory tests in the diagnosis and prognosis of acute lymphoblastic leukemia in childhood

Coronel MRC

Language: Spanish
References: 40
Page: 129-136
PDF size: 93.31 Kb.


ABSTRACT

Acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood. The use of specialized laboratory tests is a must in order to establish an exact diagnosis and a correct treatment. Because of the recent advances and knowledge of the biology of this disease those tests should routinely be used. ALL is a disease with a broad spectrum of biologic manifestations, therefore the need to perform in each and every case cytomorphology in the bone marrow cells, immunophenotype, cytogenetic and molecular biology studies is mandatory. Within the scope of laboratory testing there are also other tests to detect minimal residual disease, which can assist the clinician to detect early chemotherapy failures. The purpose of this paper is to review the routine testing that each patient with ALL should have as well as to outline the experience of our laboratory with these tests.


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