2005, Número 3
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Acta Pediatr Mex 2005; 26 (3)
Importancia del laboratorio en el diagnóstico y pronóstico de leucemia aguda linfoblástica de la infancia
Coronel MRC
Idioma: Español
Referencias bibliográficas: 40
Paginas: 129-136
Archivo PDF: 93.31 Kb.
RESUMEN
La leucemia aguda linfoblástica (LAL) es el padecimiento maligno más frecuente de la población pediátrica. Las pruebas de laboratorio para el diagnóstico y pronóstico de la LAL en la infancia son indispensables para el clínico, sobre todo por el gran avance en el estudio de la biología de esta enfermedad. Estas pruebas permiten definir el riesgo y por ende dar un mejor tratamiento a los pacientes. Este padecimiento no es una entidad única sino una expresión muy amplia de la enfermedad; por esta razón los estudios de citomorfología, inmunofenotipos y citogenética y las técnicas de biología molecular pueden ofrecer un espectro extenso del estudio con alta sensibilidad. Por otro lado se puede lograr la detección temprana de enfermedad mínima residual que hasta el momento sigue siendo un gran reto en la hemato-oncología, para detectar las fallas de la terapéutica. El propósito de este trabajo es dar a conocer al clínico las pruebas necesarias para cada paciente con LAL así como la experiencia del Laboratorio de Hemato-oncología en este tipo de exámenes.
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