Sierra-Galán LM, Sauza-Sosa JC, Shveid-Gerson D, López-Guzmán JA, Baños-Araujo JA, Soto ME

Language: Spanish
References: 21
Page: 177-184
PDF size: 251.91 Kb.

ABSTRACT

Background: Diastolic dysfunction is one of the earliest events of the ischemic cascade. Our objective was to identify the relation between coronary calcium score and the diastolic dysfunction in patients with preserved systolic function as a potential surrogate for ischemic heart disease in early stages. Methods: A retrospective, transversal, observational and comparative case series study was performed in apparently healthy subjects from the Preventive Medicine Department whom underwent clinical evaluation, laboratory tests, echocardiogram and coronary calcium score. Results: We included 100 patients, 58% were male, mean age was 69 ± 11 years. 69% had diastolic dysfunction. Median of coronary calcium score was 25 in females versus 48 in males; when diastolic dysfunction exists the cutoff for score was 60.7. A tendency in the association of the coronary calcium score with age and a significant association with diastolic dysfunction were noted. Conclusion: Coronary calcium score increases with age. A score higher than 60.7 associates with diastolic dysfunction and can suggests «incipient ischemic heart disease» even with preserved systolic function, therefore, even without other risks factors, is its advisable to start on specific actions to prevent the progression of coronary atherosclerosis.

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