2015, Number 1
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Rev Cubana Plant Med 2015; 20 (1)
Plantas consideradas útiles como hipoglicemiantes, antihipertensivas o hipolipemiantes por pacientes con enfermedades vasculares periféricas
García-Lazo G, Lauzant-Diaz E, Díaz BA, Garcia-Mesa M
Language: English
References: 29
Page: 38-47
PDF size: 124.44 Kb.
ABSTRACT
Introduction: knowing patients ‘believes about the medicinal utility of plants may provide a basis for educating them for a rational use of herb preparations.
Objective: to characterize the plants that are considered useful for antidiabetic, antihypertensive or hypolipidemic treatment among patients with peripheral
vascular diseases.
Methods: a survey was performed among patients of the National Institute of Angiology and Vascular Surgery from February through April 2007. The characteristics of the use of plants as medicinal remedies and the names of species considered useful for the treatment of diabetes, arterial hypertension and dyslipidemia were recorded.
Results: two hundred and forty five both sex adult volunteers (142 female/103 male), aged 44 to 72 years) were included in the study. More than 80 % of them
used medicinal plants at least occasionally and confided on their efficacy to treat different illnesses Fifteen species, mainly
Allium sativum L.,
Citrus aurantifolia Ch.,
Justicia pectoralis Jacq.,
Morinda citrifolia L.,
Ocinum sanctum L and
Salvia officinalis L, from 11 botanical families, were mentioned by participants. Most patients’ claims about plants´ properties have been scientifically supported in some extent, nevertheless, the majority of the pharmacological evidence relays on preclinical studies and results of clinical trials are not conclusive. The lack of standardized plant preparations with identified active principles and demonstrated clinical effectiveness are limitations for recommending their therapeutic use.
Conclusion: this study has provided the first characterization of the use of plant
products by patients with peripheral vascular diseases for medicinal purposes and
confirmed that physicians should be aware about the possibility of herb-drug
interactions that should be diagnosed. This information would aid the scientifically
supported integration of Phytotherapy to the clinical practice.
REFERENCES
Galkina E, Ley K. Immune and inflammatory mechanisms of atherosclerosis. Annu Rev Immunol. 2009;27:165-97.
Colagiuri R. Diabetes: A pandemic, a development issue or both? Expert Rev Cardiovasc Ther. 2010;8(3):305-9.
Gamboa R. Fisiopatología de la hipertensión arterial esencial. Acta Med Per. 2006;23(2):76-82.
Canalizo-Miranda E, Favela-Pérez EA, Salas-Anaya JA, Gómez-Díaz R, Jara- Espino R, Torres-Arreola LP, et al. Clinical practice guideline. Diagnosis and treatment of dyslipidemia. Rev Med Inst Mex Seg Soc. 2013;51(6):700-9.
Karou SD, Tchacondo T, Tchibozo MAD, Abdoul-Rahaman S, Anani K, Koudouvo K, et al. Ethnobotanical study of medicinal plants used in the management of diabetes mellitus and hypertension in the Central Region of Togo. Pharm Biol. 2011;49(12):1286-97.
Borokini TI, Clement M, Dickson NJ, Edagbo DE. Ethnobiological survey of traditional medicine practice for circulatory and nervous system related diseases in Oyo State, Nigeria. J Herb Med. 2013;2(6):111-20.
Matheka DM, Alkizim FO. Complementary and alternative medicine for type 2 diabetes mellitus: Role of medicinal herbs. J Diabetes Endocrinol. 2012;3(4):44-56.
Stanger MJ, Thompson LA, Young AJ, Lieberman HR. Anticoagulant activity of select dietary supplements. Nutr Rev. 2012;70:107-17.
Mutirangura P, Ruangsetakit C, Wongwanit C, Sermsathanasawadi N, Chinsakchai K. Clinical differentiation between acute arterial embolism and acute arterial thrombosis of the lower extremities. J Med Assoc Thai. 2009;92(7):891-7.
Garcia M. Antidiabetic potential of plants used in Cuba. Pharmacologyonline. 2014;1:52-62.
Garcia M. Hypolipidemic potential of plants used in Cuba. Pharmacologyonline. 2014;1:73-80.
Garcia M. Antihypertensive potential of plants used in Cuba. Pharmacologyonline. 2014;2:10-7.
García-Valido PE, Pérez-Alejo JL. Especies medicinales en el Delta Orinoco: aspectos promisorios para la medicina tradicional cubana. Quesada Pantoja J, editor. La Habana: ECIMED; 2011:275-6.
Odetola AA, Iranloye YO, Akinloye O. Hypolipidaemic potentials of Solanum melongena and Solanum gilo on hypercholesterolemic rabbits. Pakistan J Nutr. 2004;3(3):180-7.
Silva ME, Santos RC, Leary MC, Santos RS. Effect of aubergine (Solanum melongena) on serum and hepatic cholesterol and triglycerides in rats. Braz Arch Biol Technol. 1999;42(3).
Botelho FV, Enéas LR, Cesar GC, Bizzotto CS, Tavares E, Oliveira FA. Effects of eggplant (Solanum melongena) on the atherogenesis and oxidative stress in LDL receptor knock out mice (LDLR(-/-). Food Chem Toxicol. 2004;42(8):1259-67.
Guimarães PR, Galvão AMP, Batista CM, Azevedo GS, Oliveira RD, Lamounier RP, et al. Eggplant (Solanum melongena) infusion has a modest and transitory effect on hypercholesterolemic subjects. Braz J Med Biol Res. 2000;33(9).
da Silva GEC, Takahashi MH, Filho WE, Albino CC, Tasim GE, Serri LAF, et al. Ausência de efeito hipolipemiante da Solanum melongena L. (Berinjela) em pacientes hiperlipidêmicos. Arq Bras Endocrinol Metab. 2004;48(3):368-73.
Rodriguez J, Loyola JI, Maulén G, Schmeda-Hirschmann G. Hypoglycaemic activity of Geranium core-core, Oxalis rosea and Plantago major extract in rats. Phytother Res. 1994;8(6):372-4.
Angarskaya MA, Sokolova VE. The effect of plantain (Plantago major) on the course of experimental atherosclerosis in rabbits. Bull Exp Biol Med. 1963;53(4):410-12.
Yirga G. Assessment of traditional medicinal plants in Endrta District, Southeastern Tigray, Northern Ethiopia. Afr J Plant Sci. 2010;4(7):255-60.
Scull Lizama R, Miranda Martínez M, Infante Lantigua RE. Plantas medicinales de uso tradicional en Pinar del Río. Estudio etnobotánico. I. Rev Cubana Farm. 1998;2(1).
Ministerio de Salud Pública. Dirección Nacional de Farmacias. Formulario Nacional Fitofármacos y Apifármacos. Editorial Ciencias Médicas, La Habana, 2010:5-9.
Ministerio de Salud Pública. Dirección Nacional de Farmacias. Formulario Nacional Fitofármacos y Apifármacos. Editorial Ciencias Médicas, La Habana, 2010:105-7.
Ministerio de Salud Pública. Dirección Nacional de Farmacias. Formulario Nacional Fitofármacos y Apifármacos. Editorial Ciencias Médicas, La Habana, 2010:108-10.
Ministerio de Salud Pública. Dirección nacional de Farmacias. Formulario nacional Fitofármacos y Apifármacos. Editorial Ciencias Médicas, La Habana, 2010:164-5.
García-Valido PE, Pérez-Alejo JL. Especies medicinales en el Delta Orinoco: aspectos promisorios para la medicina tradicional cubana. Quesada Pantoja J, editor. La Habana: ECiMED; 2011:225-6.
Hernández Cano J, Volpato G. Herbal mixtures in the traditional medicine of Eastern Cuba. J Ethnopharmacology. 2004;90:293-316.
Arencibia-Figueroa R. Un científico popular. Capdevila Prado C, editor. La Habana: Ediciones Médicas, Centro Provincial del Libro y la Literatura; 2008:52.