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2014, Number 4

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Rev Cubana Farm 2014; 48 (4)

Evaluation of calcium and magnesium citrate from cuban dolomite

Rodríguez CJE, Martínez ÁL, Bermello CA

Language: English
References: 26
Page: 636-645
PDF size: 257.12 Kb.


ABSTRACT

Introduction: calcium and magnesium salts are used as nutritional supplements obtained from natural sources such as dolomite, which is a double complex of calcium and magnesium carbonate. In search of a calcium raw material with greater bioavailability, a process of obtaining calcium and magnesium citrate salt from dolomite deposits was developed.
Objective: to evaluate calcium and magnesium citrate from dolomite.
Methods: chemical and technological analysis, Powder X-ray Diffractometry attenuated total reflection-Fourier transform infrared spectrometry (ATR-FTIR), differential scanning calorimetry and thermogravimetric analysis were all used.
Results: the chemical analysis confirmed the existence of calcium (over 10 %), and of magnesium (4.5 and 5 %) whereas citric acid content was under 3 %, The levels of toxic metals were below the maximum allowable limits for pharmaceutical products. The density values were below those of the dolomite, with high porosity and flow deficit. The X-ray diffractomery indicated that dolomite was transformed into calcium and magnesium citrate salts whereas, the infrared spectra showed the presence of characteristic COO¯, -OH and -CH2 groups of citrates. The differential scanning calorimetry showed that salt had three endothermic peaks at 101.7 ºC, 167.1 ºC y 194.6 ºC and on the other hand, termogravimetry analysis confirmed that 30.9 % of the total mass is lost at temperatures lower than 295 ºC.
Conclusions: the presence of calcium and magnesium citrate salt is corroborated.


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