2015, Number 2
<< Back Next >>
Anales de Radiología México 2015; 14 (2)
Discriminatory capacity of tomography findings to identify pulmonary lesions due to nocardia infection
Navarro-Ballester A, Barrachina-Hidalgo S, Ambit-Capdevila S, Marco-Doménech SF
Language: Spanish
References: 24
Page: 160-171
PDF size: 623.37 Kb.
ABSTRACT
Objective: Evaluate the diagnostic value of some findings in thoracic
computed tomography, in patients with confirmed pulmonary nocardiosis,
so that, taken together, they may help distinguish it from other
conditions that may show superimposable radiological findings.
Material and methods: Subjects with microbiological diagnosis of
nocardiosis in our hospital over a 5-year period were selected. The
findings observed in tomography were collected and compared with
those observed in three comparison groups made up by pathologies
which produce superimposable image manifestations (tuberculosis,
pulmonary neoplasms, and pneumonias). We sought to establish a
model that would help distinguish, based on image findings, pulmonary
nocardiosis from other groups.
Results: We established a model which combines three variables (age,
adenopathies, and heterogeneous size of nodules) and obtained a discriminatory
capacity of 79 % compared with other alternative diagnoses.
Conclusions: although the findings in image techniques are not specific
for pulmonary nocardiosis, the grouping of findings in our model, in
a proper clinical context, may be useful in establishing a provisional
diagnosis of pulmonary nocardiosis, to the detriment of other possibilities,
and help manage therapeutic approaches pending microbiological
confirmation.
REFERENCES
Bafghi MF, Eshraghi SS, Heidarieh P, Habibnia S, Nasab MR. Nocardiosis in immune disorder disease. Malays J Med Sci 2014;21:75-6.
Saubolle MA, Sussland D. Nocardiosis: review of clinical and laboratory experience. J Clin Microbiol 2003;41:4497-501.
Alavi Darazam I, Shamaei M, Mobarhan M, Ghasemi S, Tabarsi P, Motavasseli M, et al. Nocardiosis: risk factors, clinical characteristics and outcome. Iran Red Crescent Med J 2013;15:436-9.
Muñoz J, Mirelis B, Aragón LM, Gutiérrez N, Sánchez F, Español M, et al. Clinical and microbiological features of nocardiosis 1997-2003. J Med Microbiol 2007;56:545-50.
Muricy EC, Lemes RA, Bombarda S, Ferrazoli L, Chimara E. Differentiation between Nocardia spp and Mycobacterium spp. Critical aspects for bacteriological diagnosis. Rev Inst Med Trop Sao Paulo 2014;56:397-401.
Palmieri JR, Santo A, Johnson SE. Soil-acquired cutaneous nocardiosis on the forearm of a healthy male contracted in a swamp in rural eastern Virginia. Int Med Case Rep J 2014;7:41-7.
Brown-Elliott BA, Brown JM, Conville PS, Wallace RJ Jr. Clinical and laboratory features of the nocardia spp. based on current molecular taxonomy. Clin Microbiol Rev 2006;19:259-82.
Smego RA, Gallis HA. The clinical spectrum of Nocardia brasiliensis infection in the United States. Rev Infect Dis 1984;6:164-80.
Abdelkafi S, Dubail D, Bosschaerts T, A. Brunet, G. Van Camp, M. de Marneffe, et al. Superior vena cava syndrome associated with Nocardia farcinica infection. Thorax 1997;52:492-493.
Ambrosioni J, Lew D, Garbino J. Nocardiosis: updated clinical review and experience at a tertiary center. Infection 2010; 38:89-97.
Torres HA, Reddy BT, Raad II, Tarrand J, Bodey GP, Hanna HA, et al. Nocardiosis in cáncer patients. Medicine (Baltimore) 2002;81:388-97.
Biscione F, Cecchini D, Ambrosioni J, Bianchi M, Corti M, Benetucci J. Nocardiosis en pacientes infectados por el VIH. Enferm Infecc Microbiol Clin 2005;23:419-23.
Martínez Tomás R, Menéndez Villanueva R, Reyes Calzada S, Santos Durantez M, Vallés Tarazona JM, Modesto Alapont M, et al. Pulmonary nocardiosis: risk factors and outcomes. Respirology 2007;12:394-400.
Corti ME, Villafañe-Fioti MF. Nocardiosis: a review. Int J Infect Dis 2003;7:243-50.
Oszoyoglu AA, Kirsch J, Mohammed TL. Pulmonary nocardiosis after lung transplantation: CT findings in 7 patients and review of the literature. J Thorac Imaging 2007;22:143- 8.
Santos J, Palacios R, Rivero A, García-Ordóñez MA, Aliaga L, Muniain MA, et al. Nocardiosis en pacientes con infección por VIH. Rev Clin Esp 2002;202:375-8.
Murray PR, Heeren RL, Niles AC. Effect of decontamination procedures on recovery of Nocardial spp. J Clin Microbiol 1987;25:2010-1.
Fernandez-Guerrero ML, Torres A, Díaz Curiel M, Soriano F. Successful treatment of nocardial thigh abscessand possible brain abscess with co-trimoxazole. Eur J Clin Microbiol 1985;4:430-1.
Minero MV, Marín M, Cercenado E, Rabadán PM, Bouza E, Muñoz P. Nocardiosis at the turn of the century. Medicine (Baltimore) 2009;88:250-61.
Uttamchandani RB, Daikos GL, Reyes RR, Fischl MA, Dickinson GM, Yamaguchi E, et al. Nocardiosis in 30 patients with advancedhuman immunodeficiency virus infection: clinical featuresand outcome. Clin Infect Dis 1994;18:348-53.
Bargehr J, Flors L, Leiva-Salinas C, Flohr TR, Sawyer R, Bonatti H, et al. Nocardiosis in solid-organ transplant recipients: spectrum of imaging findings. Clin Radiol 2013;68:266-71.
Berkey P, Bodey GP. Nocardial infection in patients with neoplastic disease. Rev Infect Dis 1989;11:407-12.
Black CM, Beaman BL, Donnovan RM, Goldstein E. Effect of virulent and less virulent strains of Nocardia asteroides on acid-phosphatase activity in alveolar and peritoneal macrophages maintained in vitro. J Infect Dis 1983;148:117- 24.
Blackmon KN, Ravenel JG, Gomez JM, Ciolino J, Wray DW. Pulmonary nocardiosis: computed tomography features at diagnosis. J Thorac Imaging 2011;26:224-9.