2014, Number 2
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CorSalud 2014; 6 (2)
Behavior of mortality due to aortic dissection in Cuba
Valdés DO, Hurtado MAJ, Montero GTJ, Álvarez SR, de Arazoza HA, Chao GJL
Language: Spanish
References: 45
Page: 140-147
PDF size: 473.96 Kb.
ABSTRACT
Introduction: Aortic dissection is a disease of poor prognosis, with a high mortality rate, even when it is diagnosed early and the adequate surgery is performed.
Objectives: To describe some characteristics of the patients who died due to aortic dissection in Cuba.
Method: A retrospective cross-sectional study was conducted. It included 888 deceased patients with a diagnosis of aortic dissection, who were registered in the Automated Registration and Control System of Anatomical Pathology (SARCAP, for its acronym in Spanish) in Cuba, from 1962 to 2004.
Results: The age groups from 65 to 74 and from 75 to 84 years predominated, with 266 (30.0%) and 210 (23.6%) deaths, respectively. The largest number of deaths [496 (55.9%)] occurred in the first 24 hours. Stanford type A aortic dissection was the most frequent type [535 diagnoses were made (61.1%)]. The most common underlying cause of death was aortic dissection itself (61.6 %) and the most common direct cause of death was hemopericardium (43.9%). The rate of diagnostic agreement was 33.5 % in the underlying cause and 28.8 % in direct cause.
Conclusions: During the 42 years covered by the study, the patients who died from aortic dissection in Cuba predominantly had Stanford type A dissections, were over 55 years of age and had a hospital stay of less than 2 months. The largest number of deaths occurred in the first 24 hours and the rate of diagnostic agreement was low.
REFERENCES
Carbonell Cantí C. Historia de la cirugía de la aorta torácica. En: Vaquero C, ed. Cirugía de la aorta to-rácica. Valladolid: Gráficas Andrés Martín SL, 2010; p. 15-32.
Tsai TT, Isselbacher EM, Trimarchi S, Bossone E, Pape L, Januzzi JL, et al. Acute type B aortic dissection: does aortic arch involvement affect management and outcomes? Insights from the International Registry of Acute Aortic Dissection (IRAD). Circulation. 2007;116(11 Suppl):I150-6.
Ince H, Nienaber CA. Tratamiento de los síndromes aórticos agudos. Rev Esp Cardiol. 2007;60(5):526-41.
Isselbacher EM. Enfermedades de la aorta. En: Braunwald. Tratado de Cardiología. T II. 6 ta ed. México: McGraw-Hill Interamericana, 2005; p. 1739-40.
Coselli JS, Conklin LD, LeMaire SA. Thoracoab-dominal aortic aneurysm repair: rewiew and up-date of current strategies. Ann Thorac Surg. 2002; 74(5):S1881-4; discussion S1892-8.
Golledge J, Eagle KA. Acute aortic dissection. Lan-cet. 2008;372(9632):55-66.
Vilacosta I, San Román JA, Aragoncillo P, Ferreirós J, Mendez R, Graupner C, et al. Penetrating Atheros-clerotic aortic ulcer: documentation by transeso-phageal echocardiography. J Am Coll Cardiol. 1998; 32(1):83-9.
Santo AH, Puech-Leão P, Krutman M. Trends in aortic aneurysm- and dissection-related mortality in the state of São Paulo, Brazil, 1985-2009: mul-tiple-cause-of-death analysis. BMC Public Health [Internet]. 2012 [citado 2013 Nov 14];12:859. Dis-ponible en: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527140/pdf/1471-2458-12-859.pdf
Braverman AC. Aortic dissection: prompt diagnosis and emergency treatment are critical. Cleve Clin J Med. 2011;78(10):685-96.
10.Braverman AC. Acute aortic dissection: clinician up-date. Circulation. 2010;122(2):184-8.
11.Hagan PG, Nienaber CA, Isselbacher EM, Bruckman D, Karavite DJ, Russman PL, et al. The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease. JAMA. 2000;283(7): 897-903.
12.Cury Rezende P, Borges Viana V, Benvenuti LA. Ca-so 2/2011 - Paciente joven, del sexo masculino, con cuadro de dolor torácico tipo pleurítico, hipoten-sión, sudoresis profusa, con ECG sin alteraciones isquémicas agudas y marcadores de lesión miocár-dica negativos. Arq Bras Cardiol. 2011;96(4):e62-8.
13.Kelly BS. Evaluation of the elderly patient with acute chest pain. Clin Geriatr Med. 2007;23(2):327-49.
14.Valdés Dupeyrón O, Villar Inclán A, Nafeh Abiz-Reck M, Pedroso J, Guevara González L, Chao González N, et al. Tratamiento quirúrgico de las enferme-dades de la aorta ascendente. Estudio de tres años. Rev Arg de Cir Cardiovasc. 2011;IX(1):47-59.
15.Olivert Cruz M, Romero Cabrera AJ, Bembibre Ta-boada R, Bermúdez López J. Disección aórtica. Estudio en un decenio (1987-1997). Rev Cubana Med. 2000;39(4):217-21.
16.Daily PO, Trueblood HW, Stinson EB, Wuerflein RD, Shumway NE. Management of acute aortic dis-sections. Ann Thorac Surg. 1970;10(3):237-47.
17.DeBakey ME, Beall AC, Cooley DA, Crawford ES, Morris GC, Garrett HE, et al. Dissecting aneurysms of the aorta. Surg Clin North Am. 1966;46(4):1045-55.
18.Burton EC, Phillips RS, Covinsky KE, Sands LP, Gold-man L, Dawson NV, et al. The relation of autopsy rate to physicians' beliefs and recommendations regarding autopsy. Am J Med. 2004;117(4):255-61.
19.Burton JL, Underwood JC. Necropsy practice after the «organ retention scandal»: requests, perform-ance, and tissue retention. J Clin Pathol. 2003; 56(7):537-41.
20.Sanz-Ortiz J, Mayorga M, Martín A. Autopsia clínica en Oncología: ¿está en crisis? Med Clin (Barc). 2011; 137(7):317-20.
21.Hurtado de Mendoza Amat J, Montero González TJ, Ygualada Correa I. Situación actual y perspectiva de la autopsia en Cuba. Rev Cubana Salud Pública. 2013;39(1):135-47.
22.Ladouceur M, Fermanian C, Lupoglazoff JM, Edou-ard T, Dulac Y, Acar P, et al. Effect of beta-blockade on ascending aortic dilatation in children with the Marfan syndrome. Am J Cardiol. 2007;99(3):406-9.
23.Contreras Zúñiga E, Zuluaga Martínez SX, Gómez Mesa JE, Ocampo Duque V, Urrea Zapata CA. Disec-cion aórtica: estado actual. Rev Costarric Cardiol. 2009;11(1):19-27.
24.Kahn SL, Dake MD. Stent graft management of stable, uncomplicated type B aortic dissection. Perspect Vasc Surg Endovasc Ther. 2007;19(2):162-9.
25.Ford PF, Farber MA. Role of endovascular therapies in the management of diverse thoracic aortic pa-thology. Perspect Vasc Surg Endovasc Ther. 2007; 19(2):134-43.
26.Rampoldi V, Trimarchi S, Eagle KA, Nienaber CA, Oh JK, Bossone E, et al. Simple risk models to predict surgical mortality in acute type A aortic dissection: the International Registry of Acute Aortic Dissec-tion score. Ann Thorac Surg. 2007;83(1):55-61.
27.Rogers AM, Hermann LK, Booher AM, Nienaber CA, Williams DM, Kazerooni EA, et al. Sensitivity of the aortic dissection detection risk score, a novel guide-line-based tool for identification of acute aortic dissection at initial presentation. Results from the International Registry of Acute Aortic Dissection. Circulation. 2011;123(20):2213-8.
28.Evangelista A, Padilla F, López-Ayerbe J, Calvo F, López-Pérez JM, Sánchez V, et al. Registro Español del Síndrome Aórtico Agudo (RESA). La mejora en el diagnóstico no se refleja en la reducción de la mor-talidad. Rev Esp Cardiol. 2009;62(3):255-62.
29.Song KJ, Kang SJ, Song JM, Kang DH, Song H, Chung CH, et al. Factors associated with in-hospital mor-tality in patients with acute aortic syndrome invol-ving the ascending aorta. Int J Cardiol. 2007;115(1): 14-8.
30.Suzuki T, Mehta RH, Ince H, Nagai R, Sakomura Y, Weber F, et al. Clinical profiles and outcomes of acute type B aortic dissection in the current era: lessons from the International Registry of Aortic Dissection (IRAD). Circulation. 2003;108(Suppl 1): II312-17.
31.Mehta RH, Suzuki T, Hagan PG, Bossone E, Gilon D, Llovet A, et al. Predicting death in patients with acute type A aortic dissection. Circulation. 2002; 105(2):200-6.
32.Senay S, Alhan C, Toraman F, Karabulut H, Dagde-len S, Cagil H, et al. Endovascular stent-graft treat-ment of type A dissection: case report and review of literature. Eur J Vasc Endovasc Surg. 2007;34(4): 457-60.
33.Ince H, Nienaber CA. Diagnosis and management of patients with aortic dissection. Heart 2007;93(2): 266-70.
34.Nienaber CA, Eagle KA. Aortic dissection: new fron-tiers in diagnosis and management. Part II: Thera-peutic management and follow-up. Circulation. 2003;108(6):772-8.
35.Santini F, Luciani GB, Montalbano G, Messina A, Faggian G, Mazzucco A. Acute type A aortic dis-section: an update on a still challenging disease. J Cardiovasc Med (Hagerstown). 2007;8(2):102-7.
36.Braverman AC, Thompson R, Sanchez L. Diseases of the aorta. In: Bonow RO, Mann DL, Zipes DP, Libby P, eds. Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. 9th ed. Philadelphia: Else-vier Science, 2011; p. 1309-37.
37.Hiratzka LF, Bakris GL, Beckman JA, Bersin RM, Carr VF, Casey DE, et al. 2010 ACCF/AHA/AATS/ACR/ ASA/SCA/SCAI/SIR/STS/SVM guidelines for the diagnosis and management of patients with Thora-cic Aortic Disease: A report of the American College of Cardiology Foundation/American Heart Associa- tion Task Force on Practice Guidelines, American Association for Thoracic Surgery, American College of Radiology, American Stroke Association, Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, So-ciety of Interventional Radiology, Society of Thora-cic Surgeons, and Society for Vascular Medicine. Circulation. 2010;121(13):e266-369.
38.Shojania KG, Burton EC, McDonald KM, Goldman L. Changes in rates of autopsy-detected diagnostic errors over time: A systematic review. JAMA. 2003; 289(21):2849-56.
39.Royal College of Pathologists of Australasia Autopsy Working Party. The decline of the hospital autopsy: a safety and quality issue for healthcare in Australia. MJA. 2004;180(6):281-5.
40.Spiliopoulou C, Papadodima S, Kotakidis N, Kuotse-linis A. Clinical diagnoses and autopsy findings. A retrospective analysis of 252 cases in Greece. Arch Pathol Lab Med. 2005;129(2):210-4.
41.Arce FP, Ondiviela R, Val Bernal JF. Discordancias clínico-patológicas en la autopsia. Experiencia del Hospital Marqués de Valdecilla. XXIX Reunión de la SEAP. Madrid, España; 6 Febrero 2007.
42.Gee WM. Causes of death in a hospitalized geriatric population: an autopsy study of 3000 patients. Virchows Arch A Pathol Anat Histopathol. 1993; 423(5):343-9.
43.Cameron HM, McGoogan E. A prospective study of 1152 hospital autopsies: II. Analysis of inaccuracies in clinicial diagnoses and their significance. J Pathol. 1981;133(4):285-300.
44.Fares AF, Fares J, Fares GF, Cordeiro JA, Nakazone MA, Cury PM. Clinical and pathological discrepan-cies and cardiovascular findings in 409 consecutive autopsies. Arq Bras Cardiol. 2011;97(6):449-55.
45.Battle RM, Pathak D, Humble CG, Key CR, Vanatta PR, Hill RB, et al. Factors influencing discrepancies between premortem and postmortem diagnoses. JAMA. 1987;258(3):339-44.