2015, Number 1
<< Back Next >>
Gac Med Mex 2015; 151 (1)
Estrategias ventilatorias ante el niño con síndrome de distress respiratorio agudo e hipoxemia grave
Donoso FA, Arriagada SD, Díaz RF, Cruces RP
Language: Spanish
References: 70
Page: 75-84
PDF size: 126.60 Kb.
ABSTRACT
In this review, we assemble the fundamental concepts of the use of mechanical ventilation (MV) in children with acute
respiratory failure (ARDS) and refractory hypoxemia. We also discusses topics of protective ventilation and recruitment
potential, and specifically examine the options of ventilation and/or maneuvers designed to optimize the non-aerated lung
tissue: alveolar recruitment maneuvers, positive end-expiratory pressure (PEEP) titulation, high frequency oscillatory ventilation
(HFOV), airway pressure release ventilation (APRV), aimed at correcting the mismatch ventilation/perfusion (V/Q): use of prone
position. The only pharmacological intervention analyzed is the use of neuromuscular blockers. In clinical practice, the protective
MV concept involves using an individual adjustment of the PEEP and volume tidal (V
T). Use of recruitment maneuvers and
PEEP downward titration can improve lung function in patients with ARDS and severe hypoxemia. We must keep in mind HFOV instauration as early as possible in response to failure of MV. The use of early and prolonged prone can improve gas exchange
in hopes of a better control of what caused the use of MV
REFERENCES
Esan A, Hess DR, Raoof S, George L, Sessler CN. Severe hipoxemic respiratory failure: part 1-ventilatory strategies. Chest. 2010;137(5): 1203-16.
ARDS Definition Task Force, Ranieri VM, Rubenfeld GD, et al. Acute respiratory distress syndrome: the Berlin definition. JAMA. 2012;307: 2526-33.
Villar J, Blanco J, Añón JM, et al. The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation. Intensive Care Med. 2011;37:1932-41.
López-Fernández Y, Azagra AM, de la Oliva P, et al. Pediatric Acute Lung Injury Epidemiology and Natural History study: Incidence and outcome of the acute respiratory distress syndrome in children. Crit Care Med. 2012;40(12):3238-45.
Ware LB, Matthay AM. The acute respiratory distress syndrome. N Engl J Med. 2000;242:1334-49.
Pelosi P, D’Andrea L, Vitale G, Pesenti A, Gattinoni L. Vertical gradient of regional lung inflation in adult respiratory distress syndrome. Am J Respir Crit Care Med. 1994;149(1):8-13.
Villar J, Kacmarek RM. What is new in refractory hypoxemia? Intensive Care Med. 2013;39(7):1207-10.
Mercat A, Richard JC, Vielle B, et al. Positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA. 2008;299(6):646-55.
Meade MO, Cook DJ, Guyatt GH, et al. Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA. 2008;299(6):637-45.
Fan E, Needham DM, Stewart TE. Ventilatory management of acute lung injury and acute respiratory distress syndrome. JAMA. 2005;294(22): 2889-96.
Marini J, Gattinoni L. Ventilatory management of acute respiratory distress syndrome: A consensus of two. Crit Care Med. 2004;32(1):250-5.
Tomicic V, Fuentealba A, Martínez E, Graf J, Batista Borges J. Fundamentos de la ventilación mecánica en el síndrome de distrés respiratorio agudo. Med Intensiva. 2010;34(6):418-27.
Hubmayr RD. Perspective on lung injury and recruitment: A skeptical look at the opening and collapse story. Am J Respir Crit Care Med. 2002;165(12):1647-53.
Gattinoni L, Pesenti A. The concept of ‘‘baby lung’’. Intensive Care Med. 2005;31(6):776-84.
Donoso A, Cruces P. Daño pulmonar inducido por ventilación mecánica y estrategia ventilatoria convencional protectora. Rev Chil Pediatr. 2007;78:241-52.
Terragni PP, Rosboch G, Tealdi A, et al. Tidal hyperinflation during low tidal volume ventilation in acute respiratory distress syndrome. Am J Respir Crit Care Med. 2007;175(2):160-6.
Cakar N, Akinci O, Tugrul S, et al. Recruitment maneuver: does it promote bacterial translocation? Crit Care Med. 2002;30(9):2103-6.
Richard JC, Maggiore SM, Mercat A. Clinical review: Bedside assessment of alveolar recruitment. Crit Care. 2004;8(3):163-9.
Tugrul S, Akinci O, Ozcan PE, et al. Effects of sustained inflation and postinflation positive end-expiratory pressure in acute respiratory distress syndrome: focusing on pulmonary and extrapulmonary forms. Crit Care Med. 2003;31(3):738-44.
Grasso S, Mascia L, del Turco M, et al. Effects of recruiting maneuvers in patients with acute respiratory distress syndrome ventilated with protective ventilatory strategy. Anesthesiology. 2002;96(4):795-802.
Gattinoni L, Caironi P, Cressoni M, et al. Lung recruitment in patients with the acute respiratory distress syndrome. N Engl J Med. 2006;354(17):1775-86.
Fan E, Wilcox ME, Brower RG, et al. Recruitment maneuvers for acute lung injury: a systematic review. Am J Respir Crit Care Med. 2008; 178(11):1156-63.
Arnal JM, Paquet J, Wysocki M, et al. Optimal duration of a sustained inflation recruitment maneuver in ARDS patients. Intensive Care Med. 2011;37(10):1588-94.
Pelosi P, Gama de Abreu M, Rocco PR. New and conventional strategies for lung recruitment in acute respiratory distress syndrome. Crit Care. 2010;14(2):210.
Villagrá A, Ochagavía A, Vatua S, et al. Recruitment maneuvers during lung protective ventilation in acute respiratory distress syndrome. Am J Respir Crit Care Med. 2002;165(2):165-70.
Odenstedt H, Aneman A, Kärason S, Stenqvist O, Lundin S. Acute hemodynamic changes during lung recruitment in lavage and endotoxin-induced ALI. Intensive Care Med. 2005;31(1):112-20.
Meade MO, Cook DJ, Griffith LE, et al. A study of the physiologic responses to a lung recruitment maneuver in acute lung injury and acute respiratory distress syndrome. Respir Care. 2008;53(11):1441-9.
Constantin JM, Cayot-Constantin S, Roszyk L, et al. Response to recruitment maneuver influences net alveolar fluid clearance in acute respiratory distress syndrome. Anesthesiology. 2007;106(5):944-51.
Musch G, Harris RS, Vidal Melo MF, et al. Mechanism by which a sustained inflation can worsen oxygenation in acute lung injury. Anesthesiology. 2004;100(2):323-30.
Bouhemad B, Brisson H, Le-Guen M, Arbelot C, Lu Q, Rouby JJ. Bedside ultrasound assessment of positive end-expiratory pressure-induced lung recruitment. Am J Respir Crit Care Med. 2011;183(3):341-7.
Costa EL, Borges JB, Melo A, et al. Bedside estimation of recruitable alveolar collapse and hyperdistension by electrical impedance tomography. Intensive Care Med. 2009;35(6):1132-7.
Constantin JM, Grasso S, Chanques G, et al. Lung morphology predicts response to recruitment maneuver in patients with acute respiratory distress syndrome. Crit Care Med. 2010;38(4):1108-17.
Cruces P, Donoso A, Valenzuela J, Díaz F. Respiratory and hemodynamic effects of a stepwise lung recruitment maneuver in pediatric ARDS: A feasibility study. Pediatr Pulmonol. 2013;48(11):1135-43.
Guerin C. The preventive role of higher PEEP in treating severely hypoxemic ARDS. Minerva Anestesiol. 2011;77(8):835-45.
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med. 2000;342(18):1301-8.
Mercat A, Richard JC, Vielle B, et al. Positive end-expiratory pressure setting in adults with acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA. 2008;299(6): 646-55.
Amato MB, Barbas CS, Medeiros DM, et al. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med. 1998;338(6):347-54.
Grasso S, Stripoli T, de Michele M, et al. ARDSnet ventilatory protocol and alveolar hyperinflation: role of positive end-expiratory pressure. Am J Respir Crit Care Med. 2007;176(8):761-7.
Talmor D, Sarge T, Malhotra A, et al. Mechanical ventilation guided by esophageal pressure in acute lung injury. N Engl J Med. 2008;359(20): 2095-104.
Girgis K, Hamed H, Khater Y, Kacmarek RM. A decremental PEEP trial identifies the PEEP level that maintains oxygenation after lung recruitment. Respir Care. 2006;51(10):1132-9.
Badet M, Bayle F, Richard JC, Guérin C. Comparison of optimal positive end-expiratory pressure and recruitment maneuvers during lung-protective mechanical ventilation in patients with acute lung injury/acute respiratory distress syndrome. Respir Care. 2009;54(7):847-54.
Lunkenheimer PP, Rafflenbeul W, Keller H, Frank I, Dickhut HH, Fuhrmann C. Application of transtracheal pressure oscillations as a modification of “diffusing respiration”. Br J Anaesth. 1972;44(6):627.
Lunkenheimer PP, Keller H, Wallner F, et al. Test measuring myocardial consistency using transtracheally excited oscillation of the heart caused by pressure changes. Arch Kreislaufforsch. 1972;67(1):73-83.
Boynton BR, Hammond MD, Fredberg JJ, Buckley BG, Villanueva D, Frantz ID 3rd. Gas exchange in healthy rabbits during high-frequency oscillatory ventilation. J Appl Physiol. 1989;66(3):1343-51.
Kamitsuka MD, Boynton BR, Villanueva D, Vreeland PN, Frantz ID 3rd. Frequency, tidal volume, and mean airway pressure combinations that provide adequate gas exchange and low alveolar pressure during high frequency oscillatory ventilation in rabbits. Pediatr Res. 1990;27(1):64-9.
Arnold JH, Anas NG, Luckett P, et al. High-frequency oscillatory ventilation in pediatric respiratory failure: A multicenter experience. Crit Care Med. 2000;28(12):3913-9.
Donoso A, Cruces P, Valenzuela J, Camacho J, León J. Ventilación de alta frecuencia oscilatoria es eficaz en el tratamiento de hipercapnia grave refractaria. Rev Chil Med Inten. 2006; 21:101-7.
Young D, Lamb SE, Shah S, et al. High-frequency oscillation for acute respiratory distress syndrome. N Engl J Med. 2013;368(9):806-13.
Ferguson ND, Cook DJ, Guyatt GH, et al. High-frequency oscillation in early acute respiratory distress syndrome. N Engl J Med. 2013;368(9):795-805.
Gupta P, Green JW, Tang X, Gall CM, Gossett JM, Rice TB, et al. Comparison of high-frequency oscillatory ventilation and conventional mechanical ventilation in pediatric respiratory failure. JAMA Pediatr. 2014; 168(3):243-9.
Stock MC, Downs JB, Frolicher DA. Airway pressure release ventilation. Crit Care Med. 1987;15(5):462-6.
Downs JB, Stock MC. Airway pressure release ventilation: A new concept in ventilator support. Crit Care Med. 1987;15(5):459-61.
Putensen C, Muders T, Varelmann D, Wrigge H. The impact of spontaneous breathing during mechanical ventilation. Curr Opin Crit Care. 2006;12(1):13-8.
Putensen C, Mutz NJ, Putensen-Himmer G, Zinserling J. Spontaneous breathing during ventilatory support improves ventilation-perfusion distributions in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med. 1999;159(4 Pt 1):1241-8.
Yoshida T, Rinka H, Kaji A, et al. The impact of spontaneous ventilation on distribution of lung aeration in patients with acute respiratory distress syndrome: airway pressure release ventilation versus pressure support ventilation. Anesth Analg. 2009;109(6):1892-900.
Schultz TR, Costarino AT JR AT, Durning SM, et al. Airway pressure release ventilation in pediatrics. Pediatr Crit Care Med. 2001;2(3):243-6.
Demirkol D, Karabocuoglu M, Citak A. Airway pressure release ventilation: an alternative ventilation mode for pediatric acute hypoxemic respiratory failure. Indian J Pediatr. 2010;77(11):1322-5.
Roy S, Habashi N, Sadowitz B, et al. Early airway pressure release ventilation prevents ARDS-a novel preventive approach to lung injury. Shock. 2013;39(1):28-38.
Donoso A, Fuentes I, Escobar M. Posición prono en síndrome de distress respiratorio agudo. Rev Chil Pediatr. 2002;73:34-42.
Nyrén S, Radell P, Lindahl S, et al. Lung ventilation and perfusion in prone and supine postures with reference to anesthetized and mechanically ventilated healthy volunteers. Anesthesiology. 2010;112(3): 682-7.
Fridrich P, Krafft P, Hochleuthner H, Mauritz W. The effects of long-term prone positioning in patients with trauma-induced adult respiratory distress syndrome. Anesth Analg. 1996;83(6):1206-11.
Stocker R, Neff T, Stein S, Ecknauer E, Trentz O, Russi E. Prone positioning and low-volume pressure-limited ventilation improve survival in patients with severe ARDS. Chest. 1997;111(4):1008-17.
Cruces P, Donoso A, Díaz F, López L, Valenzuela J. Tiempo-dependencia de la respuesta a posición prono prolongado en síndrome de distress respiratorio agudo grave. Rev Chil Med Inten. 2007;22:235-40.
McAuley D, Giles S, Fichter H, Perkins G, Gao F. What is the optimal duration of ventilation in the prone position in acute lung injury and acute respiratory distress syndrome? Intensive Care Med. 2002;28(4): 414-8.
Gattinoni L, Carlesso E, Taccone P, Polli F, Guérin C, Mancebo J. Prone positioning improves survival in severe ARDS: a pathophysiologic review and individual patient meta-analysis. Minerva Anestesiol. 2010; 76(6):448-54.
Guérin C, Reignier J, Richard JC, et al. Prone positioning in severe acute respiratory distress syndrome. N Engl J Med. 2013;368(23):2159-68.
Papazian L, Forel JM, Gacouin A, et al. ACURASYS Study Investigators: Neuromuscular blockers in early acute respiratory distress syndrome. N Engl J Med. 2010;363(12):1107-16.
Neto AS, Pereira VG, Espósito DC, Damasceno MC, Schultz MJ. Neuromuscular blocking agents in patients with acute respiratory distress syndrome: a summary of the current evidence from three randomized controlled trials. Ann Intensive Care. 2012;2(1):33.
Forel JM, Roch A, Marin V, et al. Neuromuscular blocking agents decrease inflammatory response in patients presenting with acute respiratory distress syndrome. Crit Care Med. 2006;34(11):2749-57.
De Jonghe B, Lacherade JC, Sharshar T, Outin H. Intensive care unit-acquired weakness: risk factors and prevention. Crit Care Med. 2009;37(10 Suppl):S309-15.