Contrasting two antibiotics schemes in children with septic shock spotted fever  of the Rocky Mountains

Norberto Gómez Rivera; Ignacio Fonseca Chon; María Guadalupe García Zárate; César Omar Gómez Figueroa; Luis Villalobos García

2014, Number 6

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Rev Mex Pediatr 2014; 81 (6)

Contrasting two antibiotics schemes in children with septic shock spotted fever of the Rocky Mountains

Gómez RN, Fonseca CI, García ZMG, Gómez FCO, Villalobos GL

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Language: Spanish
References: 21
Page: 204-208
PDF size: 135.91 Kb.

ABSTRACT

Objective: To compare two treatment guidelines to differ in handling antibiotics in patients with septic shock Spotted Fever Rocky Mountain (RMSF).
Material and methods: Design; cases and controls. We compare 2 samples at the convenience of the records of 40 patients in septic shock by RMSF treated based on a therapeutic guide that should fix septic shock considering the combination of ciprofloxacin - doxycycline, with a control group of 20 patients with RMSF treated using doxycycline plus ceftriaxone.
Results: Correction of serum lactate was achieved in 85% in the study group compared to 10% in the control group, p = 0.04. Mean arterial pressure (MAP) in the study group at 90% compared to 20% in the control group p = 0.03. Mortality and correction of platelet count there was no significant difference p = 0.23 and 0.28 respectively in 48 hours.
Conclusions: The management of septic shock by RMSF study group showed better stabilization within 48 hours.

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