medigraphic.com
ISSN 2007-8560 (Print)
Órgano Oficial de Difusión Científica de la Federación Mexicana de Colegios de Ortopedia y Traumatología, A.C. (FEMECOT)

2014, Number 4

<< Back Next >>

Ortho-tips 2014; 10 (4)

Substitutes for tendons and ligaments

Garín ZDE, Reyes PE

Language: Spanish
References: 22
Page: 227-234
PDF size: 320.96 Kb.


ABSTRACT

Tendons transmit forces from muscle to bone and provide the function of joint mobility. Ligaments transmit forces from bone to bone and unlike tendons, they provide stability to the joint. The incidence of tendon and ligament injuries is very common in our population, mainly in the male patient because of the type of sport they play, and they are common in orthopedic surgery care. Tendons and ligaments are poorly vascularized tissues therefore have little ability to repair. So in acute injuries and chronic injuries, surgical reconstruction of tendon and ligament defects is a complicated situation. Autografts are still gold standard but allografts and xenografts have been introduced as an alternate option but they have lower therapeutic value than autografts. All these available options have their own significant limitations. Tissue engineering is a newer option and can be divided into four categories: scaffolds, growth factors, stem cells and gene therapy. Using each one or a combination of them has provided the new insights in orthopedic surgery. In this review we will discuss the various options that exist and which there is more experience.


REFERENCES

  1. Sharma P, Maffulli N. Tendon injury and tendinopathy: healing and repair. J Bone Joint Surg Am. 2005; 87: 187-202.

  2. Guía de práctica clínica. Manejo de las lesiones ligamentarias traumáticas en rodilla. México: Secretaría de Salud; 2009.

  3. Moshiri A, Oryan A. Role of tissue engineering in tendon reconstructive surgery and regenerative medicine: current concepts, approaches and concerns. Hard Tissue. 2012; 1: 11.

  4. Moshiri A, Oryan A. Tendon and ligament tissue engineering, healing and regenerative medicine. J Sports Med Doping Stud. 2013; 3: 126. doi: 10.4172/2161-0673.1000126.

  5. Moshiri A, Oryan A, Meimandi-Parizi AH, Silver IA, Tanideh N, et al. Effectiveness of hybridized nano and micro-structure biodegradable and biocompatible collagen-based, three-dimensional bioimplants, in repair of a large tendon-defect model in rabbits. J Tissue Eng Regen Med. 2013. doi: 10.1002/term.1740.

  6. Ronel DN, Newman MI, Gayle LB, Hoffman LA. Recent advances in the reconstruction of complex Achilles tendon defects. Microsurgery. 2004; 24: 18-23.

  7. Palmer EM, Beilfuss BA, Nagai T, Semnani RT, Badylak SF, et al. Human helper T cell activation and differentiation is suppressed by porcine small intestinal submucosa. Tissue Eng. 2002; 8: 893-900.

  8. Oryan A, Moshiri A, Meimandi-Parizi AH. Graft selection in ACL reconstructive surgery: past, present and future. Current Orthopaedic Practice. Curr Orthop Pract. 2013; 24: 321-333.

  9. Veillette CJ, Cunningham KD, Hart DA, Fritzler MJ, Frank CB. Localization and characterization of porcine patellar tendon xenograft antigens in a rabbit model of medial collateral ligament replacement. Transplantation. 1998; 65: 486-493.

  10. ACL Graft Choices. Disponible en: http://www.orthoassociates.com/SP11B35/

  11. Shearn JT, Kinneberg KR, Dyment NA, Galloway MT, Kenter K, et al. Tendon tissue engineering: progress, challenges, and translation to the clinic. J Musculoskelet Neuronal Interact. 2011; 11: 163-173.

  12. Johnson D. Graft choice for ACL reconstruction. ISAKOS Innovations. 2014.

  13. Badylak SF, Valentin JE, Ravindra AK, McCabe GP, Stewart-Akers AM. Macrophage phenotype as a determinant of biologic scaffold remodeling. Tissue Eng Part A. 2008; 14: 1835-1842.

  14. Petrigliano F, McCallister D, Wu B. Tissue engineering for ACL reconstruction: a review of current strategies. Arthroscopy. 2006; 22 (4): 441-451.

  15. Dubey N, Letourneau PC, Tranquillo RT. Neuronal contact guidance in magnetically aligned fibrin gels: effect of variation in gel mechano-structural properties. Biomaterials. 2001; 22: 1065-1075.

  16. Oryan A, Moshiri A. Exogenous acellular synovial fluid as a new therapeutic option in tissue engineering and regenerative medicine. Hard Tissue. 2013; 2: 21.

  17. Kumar K, Maffulli N. The ligament augmentation device: an historical perspective. Arthroscopy. 1999; 15 (4): 422-432.

  18. Moshiri A, Oryan A, Meimandi-Parizi A. Role of stem cell therapy in orthopaedic tissue engineering and regenerative medicine: a comprehensive review of the literature from basic to clinical application. Hard Tissue. 2013; 2: 31.

  19. Sarrafzadehrezaei F, Oryan A, Dehghani S. Effects of electrical stimulation on biomechanics of partial and completed ruptured tendon. Res Med. 1999; 23: 169-175.

  20. Schwabe P, Greiner S, Ganzert R, Eberhart J, Dähn K, et al. Effect of a novel nonviral gene delivery of BMP-2 on bone healing. Scientific World Journal. 2012; 2012: 560142.

  21. Heyde M, Partridge KA, Oreffo RO, Howdle SM, Shakesheff KM, et al. Gene therapy used for tissue engineering applications. J Pharm Pharmacol. 2007; 59: 329-350.

  22. Radice F, Yánez R, Gutiérrez V, Pinedo M, Rosales J, Coda S. Uso de concentrado autólogo rico en factores de crecimiento en la reconstrucción del LCA. Artroscopia virtual. 2008; 15 (1): 31-40.




2020     |     www.medigraphic.com