medigraphic.com
ISSN 1810-2352 (Print)

2013, Number 4

<< Back

Rev Cub Med Int Emerg 2013; 12 (4)

Bacterial meningoencefalitis behavior in the Pediatric Hospital of Centro Habana, 2000-2012

Portuondo BE, Pérez OM, Marchena BJJ

Language: Spanish
References: 26
Page:
PDF size: 280.92 Kb.


ABSTRACT

Introduction: Bacterial Meningoencefalitis still are an important cause of morbidity and mortality and the main part of its victims are children. Objective: To analyze the behaivior of bacterial Meningoencefalitis. Method: We performed a retrospective, descriptive study of the morbidity and mortality of bacterial meningoencefalitis (MEB) in the Pediatric University Hospital of Centro Habana (HPCH) in the period January 2000 to June 2012 with the aim of analyzing MEB behavior regarding: risk factors, clinical characteristics, bacterial isolation, antibiotic therapy and complications. Relationship with mortality was established. Results: Of the 70 patients, 40 were confirmed and 30 suspicious. Survivals predominated (61) over the non survivals (9) and the highest number of deaths were in children less than 2 years with six deaths. The groups of age with the highest incidence were 5-18 years (27) and less than 2 years (24). Of all deceased, 77.7% had more than one risk factor and 60.7% who survived not (p <.05). The 85.2% (52) of the survivals had no complications but all deceased patients had more than one immediate complication (p<0.05) late complications were below 12% in the survivals. The most common causative agent was the pneumococcus with well established relationship with mortality (p<05). The antibiotic therapy of ceftriaxone plus vancomycin was used in 47 (67%) of children treated and was effective (p<.05). Conclusions: The mortality in our study is closely related to age and other risk factors, the presence of immediate complications and the etiologic agent


REFERENCES

  1. Dickinson Menesses FO, Pérez AE. Meningoencefalitis Bacterianas en la población infantil Cubana: 1998–2000. Rev Cubana Pediatría. 2002;75(2):106–14.

  2. Ceyhan M, Yildirim I, Balmer P, Borrow R, Dikici B, Turgut M, et al. A prospective study of etiology of childhood acute bacterial meningitis, Turkey. Emerg Infect Dis. 2008;14(7):1089–96.

  3. Baquero–Artigao F, López RV, Martin FC. Meningitis Bacteriana. Hospital Infantil La Paz. Madrid. An Pediatr Contin. 2008;6:47–57.

  4. Programa Nacional de prevención y control de Síndrome Neurológicos Infecciosos. La Habana: MINSAP; 1999.

  5. Thigpen MC, Whitney CG, Messonnier NE, Zell ER, Lynfield R, Hadler JL, et al. Bacterial meningitis in the United States, 1998–2007. N Engl J Med. 2011;364(21):2016–25.

  6. Davenport MC, Del Valle M, Gallegos P, Kannemann AL, Bokser VS. Meningitis bacteriana: factores de riesgo para el desarrollo de complicaciones agudas. Arch Argent Pediatr [revista en Internet]. 2007 [citado 30 Mar 2012];105(5):405-10. Disponible en: http://www.scielo.org.ar

  7. Absalom A, Schulenburg E. Infections of the central nervous system. Anesth Intensive Care. 2009;10(3):144–7.

  8. Ziailuc. Lewin JJ. Update in the diagnosis and management of central nervous system infections. Neurol Clin. 2008,26:427–68.

  9. Calvano TP, Huspenthal DR, Renz EM, Wolf SE, Murray CK. Central nervous system infections in patients with severe burns. Burns. 2010;36:688–91.

  10. Kim K. New diagnostic and Therapeutic options in Bacterial meningitis in infants and children. Minerva Pediátrica. 2009;61(5):531–48.

  11. Biaukula V, Tikodoudua L, Azzopardi K, Seuduadua A, Temple B, Russel F, et al. Meningitis in Children in Fiji: Etiology, epidemiology and neurological sequel. Int J Infect Dis. 2012;16(4):e289–95.

  12. Álvarez Fumero Roberto, Manresa Gómez Dania Luisa, Castro Pacheco Bertha Lidia, Pérez Orta Miosotis, Rojo Casares Ibis, Quintana Jardines Ibrahim. Manejo hospitalario de la meningoencefalitis bacteriana por S. Pneumoniae. Rev Cubana Pediatr [revista en la Internet]. 2003 Dic [citado 20 Ene 2013]; 75(4):[aprox. 8 p.] Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S003475312003000400005&lng=es

  13. Namani S, Koci R, Dedushi K. The outcome of bacterial meningitis in children is related to the initial antimicrobial therapy. Turk J Pediatr. 2010;52(4):354–9.

  14. Blaquer J, Solé–Violán J, Carvajal J, Lucena F. Infecciones comunitarias que requieren ingreso en UCI. Med Intensiva. 2010;34(6):388–96.

  15. Rajapaksa S, Starr M. Meningococcal sepsis. Aust Fam Physician. 2010;39(5):276–8.

  16. Curtis S, Stobart K, Vandermeer B, Sinel DL and Klassen T. Clinical features suggestive of meningitis in children: A systematic rewiev of prospective data. Pediatrics. 2010;126(5):952–60.

  17. Antoniuk SA, Zanon Franca M, Tannous Tahan T, Oliveira Rossoni AM, Dal–Ri Moreira S, Rodrigues Cruz S et al. Estudio de 312 niños con meningitis atendidos en un Hospital Universitario en el Sur de Brazil. Medicina (Buenos Aires). 2009;69(1):127–32.

  18. Edmond K, Dieye Y, Griffiths UK, Fleming J, Ba O, Diallo N, et al. Prospective cohort study of disabling sequel and quality of life in children with bacterial meningitis in urban Senegal. Pediatr Infect Dis J. 2010;29(11):1023–9.

  19. Vasilopoulou VA, Karanika M, Theodoridou K, Katsioulis , Theodoridou MN, Hadjichristodoulou CS. Prognostic factors related to sequel in childhood bacterial: data from a Greek meningitis registry. BMC Infect Dis. 2011;11:214

  20. Nigrovic LE, Kuppermann N, Marley R. Children with bacterial meningitis presenting the emergency deparment during the Pneumococcal vaccine era. Academic Emergency Medicine. 2008;15:522–8. doi:10.1111/j.1553- 2712.2008.00117.

  21. García RG. Meningitis Bacteriana en niños, Instituto de salud del niño. Lima–Perú: 1997–2002. Pediátrica. 2005;7(1):12–7.

  22. Gonzales S. Complicaciones de la Meningoencefalitis Bacteriana en el Hospital de niños Dr. Ricardo Gutiérrez. Buenos Aires, 1992–2003. 34 Congreso Argentino de Pediatría. [Internet] 2006 [citado 30 Mar 2012]. Disponible en: http://www.sap.org.ar

  23. Ramakrishnari M, Ulland AJ, Steinhardt LC, Moïsi JC. Sequelae due to Bacterial meningitis among African Children: A systematic literature review. BMC Medicine. 2009;7:47–64.

  24. Soult JA, Rangel C, Muñoz M, Parrilla JS, Díaz F, López JD, et al. Meningitis neumocócica: características epidemiológicas, clínicas y bacteriológicas. An Esp Pediat. 2001;4:315–20.

  25. Sakata H, Sato Y, Nosmoyama M, Haruta T, Ouchi K, Sunakawa K, et al. Result of a multicenter survey of diagnosis and treatment for bacterial meningitis in Japan. J Infect Chemother. 2009;61(5):531–48.

  26. Brizzi K, Hines EM, McGowan KL, Shah SS. Diagnosis accuracy of cerebrospinal fluid Gram satin in children with suspected bacterial meningitis. Pediatr Infect Dis J. 2012;31(2):195–7.




2020     |     www.medigraphic.com