2013, Number 6
<< Back Next >>
Rev Invest Clin 2013; 65 (6)
Life styles associated cognitive impairment. Study from the community pharmacy
Climent MT, Vilaplana AM, Arnedo A, Vilar J, Moreno-Royo L
Language: Spanish
References: 37
Page: 500-509
PDF size: 163.00 Kb.
ABSTRACT
Objective. Frequency of cognitive impairment among people
over 65 years old in community pharmacy. Study of asssociated
factors, referral of cases to the specialist and inclusion
in a program of health education.
Material and methods.
Cross-sectional study of prevalence, frequency, conducted in
four pharmacies (two urban and two rural pharmacies)
in the Autonomous Community of Valencia. Participants:
people over 65 years old who come to the pharmacy and who
agree to participate in the study after signing an informed
consent. It is used as the initial screening test, the Short
Portable Mental State Questionnaire of Pfeiffer. Pfeiffer positive
cases undergo a second test (Mini-Mental State Examination,
NORMACODEM version). A questionnaire designed
specifically for the study has been used to collect information.
It includes questions to gain demographic data, questions
on lifestyle and chronic diseases. We used analysis
logistic regression multilevel.
Results. 245 patients have
participated (76% of respondents). 12.65% were detected to
have cognitive impairment. In the Logistic regression analysis
multivariate there is a relation between cognitive impairment
and some variables: age, lack of reading habit,
unusual reading habit, sleeping less than 6 or more than 8
hours a day. Only 12.9% wanted to be referred for clinical
evaluation and 42% were included in a cognitive training
program.
Conclusions. There are asssociation between lifestyle
habits that are modifiable and cognitive impairment.
REFERENCES
Alzheimer’s Disease International. World Alzheimer Report 2009-Executive Summary. Disponible en: http:// www.alz.co.uk/research/files/WorldAlzheimerReport ExecutiveSummary.pdf
García FJ, Sánchez MI, Pérez A, et al. Prevalencia de demencia y de sus subtipos principales en sujetos mayores de 65 años: efecto de la educación y ocupación. Estudio Toledo. Med Clin (Barc) 2001; 116: 401-7.
Fernandez M, Castro-Flores J, Perez-de Las Heras S, Mandaluniz- Lekumberri A, Gordejuela M, Zarranz J. Prevalence of dementia in the elderly aged above 65 in a district in the Basque Country. Rev Neurol 2008; 46: 89-96.
Boada M, Peña Casanova J, Bermejo F, et al. Coste de los recursos sanitarios de los pacientes en régimen ambulatorio diagnosticados de enfermedad de Alzheimer en España. Med Clin (Barc) 1999; 113: 690-5.
Cabeza R, Nyberg L. Neural bases of learning and memory: functional neuroimaging evidence. Curr Opin Neurol 2000; 13: 415-21.
Rami L, Molinuelo JL, Sánchez-Valle R, Bosch B, Villar A. Screening for amnestic mild cognitive impairment and early Alzheimer’s disease with M@T (Memory Alteration Test) in the primary care population. Int J Geriatric Psychiatry 2007; 22(4): 293-304.
Ashford JW, Mortimer JA. Non-familial Alzheimer’s disease is mainly due to genetic factors. J Alzheimer Dis 2002; 4: 169- 77.
Lopes MA, Bottino CM. Prevalence of dementia in several regions of the world: analysis of epidemiologic studies from 1994 to 2000. Arq Neuropsiquiatr 2002; 60: 61-9.
Schmand B, Smit J, Lindeboom J, et al. Low education is a genuine risk factor for accelerated memory decline and dementia. J Clin Epidemiol 1997; 50(9): 1025-33.
10, Angevaren M, Aufdemkampe G, Verhaar HJJ, Aleman A, Vanhees L. Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment. Cochrane Database of Systematict Reviews 2008. DOI:10.1002/14651858.CD005381.pub3.
Llautenschlager NT, Cox KL, Flicker L, et al. Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial. JAMA 2008; 300: 1027-37.
Jobe JB, Smith DM, Ball K, et al. ACTIVE: a cognitive intervention trial to promote independence in older adults. Control Clin Trial 2001; 22: 453-79.
Ball K, Berch DB, Helmers KF, et al. Advanced Cognitive Training for Independent and Vital Elderly Study Group. Effects of cognitive training interventions with older adults: a randomized controlled trial. JAMA 2002; 288: 2271-81.
Ohayon MM, Vecchierini MF. Daytime sleepiness and cognitive impairment in the elderly population. Arc Intern Med 2002; 162: 201-8.
Cricco M, Simonsick EM, Foley DJ. The impact of insomnia on cognitive functioning in older adults. J Am Geriatr Soc 2001; 49: 1185-9.
Benito-León J, Bermejo-Pareja F, Vega S, Louis ED. Total daily sleep duration and the risk of dementia: a prospective population- based study. Eur J Neurol 2009; 16: 990-7.
Faubel R, López-García E, Guallar-Castillón P, Graciani A, Banegas JR, Rodríguez-Artalejo F. Usual sleep duration and cognitive function in older adults in Spain. J Sleep Res 2009; 18(4): 427-35.
Hughes T, Ganauli M. Factores de riesgo de demencia en la vejez, modificables en las etapas medias de la vida. Rev Neurol 2010; 51(5): 259-62.
Kloppenborg RP, Van der Berg E, Kappelle LJ, Biessels GJ. Diabetes and other vascular risk factors for dementia: Which factor matters most? A systematic review. Eur J Pharmacol 2008; 585: 97-108.
Contador I, Fernández-Calvo B, Ramos F, Tapias-Merino E, Bermejo-Pareja F. El cribado de la demencia en atención primaria. Rev Neurol 2010; 51: 677-86.
Regidor E. La clasificación de clase social de Goldthorpe: Marco de referencia para la propuesta de medición de la clase social del grupo de trabajo de la Sociedad Española de Epidemiología. Rev Esp Salud Pública 2001; 75: 13-22.
Sabater Hernández D, Silva Castro MM, Faus Dáder MJ. Guía de seguimiento farmacoterapéutico: método Dáder. 3a Ed. Granada: Grupo de Investigación en Atención Farmacéutica. Universidad de Granada; 2007. Disponible en: http://atencionfarmaceutica- ugr.es [Consultado 10 de marzo 2009].
Martínez de la Iglesia J, Duenas Herrero R, Onis Vilches MC, Taberna CA, Colomer CA, Luque RL. Adaptación y validación al castellano del cuestionario de Pfeiffer (SPMSQ) para detectar la existencia de deterioro cognitivo en personas mayores de 65 años. Med Clin (Barc) 2001; 117: 129-34.
Blesa R, Pujol M, Aguilar M, et al. NORMACODEM Group. NORMAlisation of Cognitive and Functional Instruments for DEMentia. Clinical validity of the “mini-mental state” for Spanish communities. Neuropsychol 2001; 39(11): 1150-7.
Iracleous P, Nie JX, Tracy CS, et al. Primary care physicians’ attitudes towards cognitive screening: findings from a national postal survey. Int J Geriatr Psychiatr 2010; 25: 23-9.
Mitchell AJ. A meta-analysis of the accuracy of mini-mental state examination in the detection of dementia and mild cognitive impairment. J Psychiatr Res 2009; 43: 411-31.
Brodaty H, Low LF, Gibson L, Burns K. What is the best dementia screening instrument for general practicioners to use? Am J Geriatr Psychiatry 2006; 14: 391-400.
Millán-Calenti JC, Tubío J, Pita-Fernández S, Rochette S, Lorenzo T, Maseda A. Prevalence of cognitive impairment: effects of level of education, age, sex and associated factors. Dement Geriatr Cogn Disord 2009; 28: 455-60.
Olivera J, Benabarre S, Lorente T, et al. Prevalence of psychiatric symptoms and mental disorders detected in primary care in an elderly Spanish population. The PSICOTARD Study: preliminary findings. Int J Geriatr Psychiatry 2008; 23: 915-21.
Hervás A, Arizcuren MA, García de Jalón E, Tiberio G, Forcén T. Influencia de variables socio-sanitarias en la situación del estado cognitivo y de ánimo en los pacientes geriátricos de un centro de salud. Anales Sis San Navarra 2003; 26: 211-23.
Wilson RS, Mendes De Leon CF, Barnes LL, et al. Participation in cognitively stimulating activities and risk of incident Alzheimer disease. JAMA 2002; 287: 742-8.
Scarmeas N, Levy G, Tang MX, et al. Influence of leisure activity on the incidence of Alzheimer’s disease. Neurology 2001; 57: 2236-42.
Willis SL, Tennstedt SL, Marsiske M, et al. ACTIVE Study Group. Long-term effects of cognitive training on everyday functional outcomes in older adults. JAMA 2006; 296: 2805-14.
Salgado A, Guillén F, Ruipérez I. Manual de Geriatría. 3a Ed. Barcelona: Edit Masson; 2002, p. 628.
Foley D, Monjan A, Masaki K, et al. Daytime sleepiness is associated with 3-year incident dementia and cognitive decline in older Japanese-American men. J Am Geriatr Soc 2001; 49(12): 1628-32.
Merlino G, Piani A, Gigli GL, et al. Daytime sleepiness is associated with dementia and cognitive decline in older Italian adults: a population-based study. Sleep Med 2010; 11(4): 372-7.
Lobo A, Saz P, Marcos G, et al. Revalidación y Normalización del Mini-Examen Cognoscitivo (primera versión en castellano del Mini-Mental Status Examination) en la población general geriátrica. Med Clin (Barc) 1999; 112: 767-74.