Mercado-Uribe MC, Martínez-Arce PA, Guerrero-Becerra M, Luévanos-Velázquez A, Candelas-Delgado E, Hernández-Flores MS, Plasencia-Hernández A

Language: Spanish
References: 32
Page: 206-214
PDF size: 1001.50 Kb.

ABSTRACT

Introduction. Infectious endocarditis (IE) is an infection in the heart's endocardial surface, indicating the presence of microorganisms in the lesion.
Material y Methods. Retrospective cohort. Consecutive non-random sample in episodes of IE in children ‹14 years of age, Jan 2006 – Jun 2013. We registered age, sex, risk factors for the community and nosocominal IE. The final evolution was measured based on heart surgical interventions, recurring IE and complications: heart and kidney failure, neurological events, embolic and mortality.
Results. We registered 34 episodes in 33 children, 100% defined IE using modified Duke Criteria. The isolated agents were from nosocomial origin in 96%, Staphylococcus (33%), gram negative bacilli (23%), Candida and Enterococcus (17%) . The age group with higher frequency was minors aging under 1 year old. One case (2.9%) had an early IE recurrence and perished. We registered late mortality in 6 case (17.6%) with a mean of 96.8 days. Enterococcusfaecium was associated to higher mortality or the need of resection of vegetation (RR 3 I.C. 95% 0.85 – 10.6) the risk of neurological events was higher when infected by Candidaalbicans (RR 8.7; 1.91-39.65). The incidence rate in IE in our hospital increased in the past 2 years from 0.34 to 1.07 x 1000 admittances.
Discussion. The microorganism involved is predictor of mortality or need of surgery, more than recurring IE.

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