Canciano CE, Valdés BS, Vásquez CN, Fabré NRA

Language: Spanish
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ABSTRACT

Introduction: epilepsy is incident pathology in middle age women with scarce reports in the Cuban population.
Objectives: to define predictors of quality of life in epileptic middle-age women in menopause and menopause consultation at Flores Betancourt Policlinic in Artemisa from January 2011 to October 2013.
Methods: a control case study was conducted selecting at random 120 patients who were pair up according to age to form two groups of 60 subjects each; Group A (diagnosed with epilepsy under anticonvulsant treatment), Group B (non-epileptic). Quality of life was used as dependent variable; and marital status, occupation, education, presence of depression, number of pregnancies, number of children, severity and duration of menopause, time of menopause were used as independent variables as well as other conditions associated to a mean follow up of 15.5 ± 2.5 months (range: 0.03-18.2).
Results: 55.8 % of the total was depressed, which increased 4.7 times (IC 2.7-5) in the epileptic subjects with association among variables (Mc Nemar Z = 4.87 p=0.02). Intense climacteric symptoms (OR 5.7 IC 4.7-6.6) for more than one year (OR 4.4 IC 4.2-5.2) were the entities with more causal relationship in group A. Uncontrolled hypertension prevailed among the epileptic subjects (OR 3.2 IC 2.6-3.1) who presented higher frequency of osteoporosis (71.1%). Menopause before age 43 was the variable of more weight in the prognostic analysis (Exp [B] 70.123 IC 12.456- 88.987). Menopause before age 43 was the most significant variable in prognostic analysis.
Conclusions: epileptic middle aged women face many physical and psychosocial difficulties early worsen their quality of life.