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2014, Number 2

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Revista Cubana de Obstetricia y Ginecología 2014; 40 (2)

Epidemiological and perinatal profile of preeclampsia patients

Sáez CVC, Pérez HMT

Language: Spanish
References: 27
Page: 155-164
PDF size: 92.54 Kb.


ABSTRACT

Introduction: preeclampsia is a major obstetric problem that carries significant morbidity and maternal and perinatal mortality due to associated systemic disorders.
Objective: to compare maternal and perinatal outcomes in pregnant women who had preeclampsia in their different clinical presentations.
Methods: a prospective, descriptive, cross-sectional study was conducted at Enrique Cabrera hospital from January 1st, 2010 to December 31st 2011. Out of the pregnant women with hypertensive disorders (n = 293), those with preeclampsia (n = 89) were chosen; and they were divided into three groups, mild preeclampsia (n = 30), severe preeclampsia (n = 48) and superimposed preeclampsia (n = 11). Epidemiological, obstetric, and perinatal variables were processed by the SPSS-11, 5 statistical systems, using descriptive statistics, comparison of proportions by Chi-square test and the estimated mean of quantitative variables with ANOVA-Eta, considering the statistically significant difference p ≤ 0.05.
Results: the adolescents had more severe preeclampsia (25 %) and ≥ 35 year old patients in the superimposed preeclampsia (p = 0.002), obesity also prevailed in the superimposed preeclampsia (54.5 %, p = 0.01). Most of the patients in the mild PE group (60 %) and severe preeclampsia (64.6 %) were nulliparous, p = 0.009. Prematurity index of severe preeclampsia (43.8 %, p = 0.005) was significant; cesarean delivery was high in all groups, mainly in severe preeclampsia (93.8 %, p = 0.000). The mean birth weight was significantly lower in severe preeclampsia (2 451 g, p = 0.01).
Conclusions: there were no major differences in perinatal outcomes among patients who were enrolled with various degrees of preeclampsia severity.


REFERENCES

  1. Zhang J, Meikle S, Trumble A. Severe Maternal Morbidity Associated with Hypertensive Disorders in Pregnancy in the United States. Hypertension in pregnancy. 2003;22(2):203-12.

  2. Kuklina EV, Ayala C, Callaghan WM. Hypertensive Disorders and Severe Obstetric Morbidity in the United States. Obstet Gynecol. 2009;113(6):1299-306.

  3. Zhang WH, Alexander S, Bouvier-Colle MH, Macfarlane A. Incidence of severe pre-eclampsia, postpartum haemorrhage and sepsis as a surrogate marker for severe maternal morbidity in a European population-based study: the MOMS-B survey. BJOG. Jan 2005;112:89-96.

  4. Leeners B, Neumaier-Wagner P, Kuse S, Mütze S, Rudnik-Schöneborn S, Rath W, et al. Recurrence risks of hypertensive diseases in pregnancy after HELLP syndrome. Journal Of Perinatal Medicine [serial on the Internet]. 2011 Nov [cited March 10 2013];39(6):673-8. Available from: http://search.ebscohost.com/login.aspx?direct=true&db=mnh&AN=21809897&lang =es&site=ehost-live

  5. Nelson MS, Greer AI. Hypertensive disorders of pregnancy. Preventative, immediate and long-term management. Expert Rev. Pharmacoeconomics Outcomes Res. 2006;6(5):541-54.

  6. Vargas HVM, Acosta AG, Moreno EMA. La preeclampsia un problema de salud pública mundial. Rev Chil Obstet Ginecol. 2012 [citado 14 Jul 2013];77(6):471-6. Disponible en: http://www.revistasochog.cl/files/pdf/DOCUMENTOS029.pdf

  7. Lewis G. (ed). Saving Mothers' Lives: Reviewing maternal deaths to make motherhood safer: 2006-2008. The Eighth Report of the Confidential Enquiries into Maternal Deaths in the United Kingdom. BJOG. 2011;118(Suppl 1):30-56.

  8. Goldenberg RL, Culhane JF, Iams JD, Romero R. Epidemiology and causes of preterm birth. Lancet. 2008;371:75-84.

  9. Dekker GA, Shalem Y, Lee SY, North RA, McCowan LM, Simpson NAB, et al. Risk Factors for Preterm Birth in an International Prospective Cohort of Nulliparous Women. Plos One. 2012;7(7):1-9.

  10. Sáez CV. Caracterización del parto pretérmino en el hospital "Enrique Cabrera". Rev Cubana Obstet Ginecol. 2013 [citado: 10 Sep 2013];39(Supl). Disponible en : http://bvs.sld.cu/revistas/gin/vol39_sup_13/gin%20%20obstet%20supl02.htm# gin18.

  11. Díaz Martínez LA, Díaz Pedraza NM, Serrano Díaz NC. El pronóstico de los hijos de madres con preeclampsia. Parte 1: Efectos a corto plazo. Arch Argent Pediatr. 2011;109(5):423-8.

  12. Sibai B, Dekker G, Kupferminc M. Pre-eclampsia. Lancet. 2005;365:785-99.

  13. Langenveld J, Ravelli ACJ, Van Kaam AH, Van der Ham DP, Van Pampus MG, Porath M, et al. Neonatal outcome of pregnancies complicated by hypertensive disorders between 34 and 37 weeks of gestation: a 7 year retrospective analysis of a national registry. Am J Obstet Gynecol. 2011 [citado 14 Jul 2013];205:540.e1-7. Disponible en: http://download.journals.elsevierhealth.com/pdfs/journals/0002- 9378/PIIS0002937811009045.pdf

  14. Espinoza J, Romero R, Nien JK, Gómez R, Kusanovic JP, Gonçalves LF, et al. Identification of patients at risk for early onset and/ or severe pre-eclampsia with the use of Uterine artery Doppler velocimetry and placental growth factor. Am J Obstet Gynecol. 2007 Apr;196(4):1-27.

  15. Di Marco I, Basualdo MN, Di Pietrantonio E, Paladino S, Ingilde M, Domergue G, et al. Guía de práctica clínica: estados hipertensivos del embarazo 2010. Rev Hosp Mat Inf Ramón Sardá. 2011;30(1):70-93.

  16. Martínez Sánchez LA, Agudelo Vélez CA, Rodríguez Gázquez MA, Cardona VJ, Becerra Uribe DE, Palacio GD, et al. Perfil clínico y epidemiológico de pacientes con preeclampsia atendidas en una clínica privada de Medellín, Colombia (2005-2010). Clin Invest Gin Obst. 2013 [citado 18 Jul 2013]. Disponible en: http://dx.doi.org/10.1016/j.gine.2013.03.005

  17. Suárez González JA, Gutiérrez Machado M, Cairo González V, Bravo Torres Y, Corrales Gutiérrez A, Tempo Alberto C. Comportamiento materno y perinatal de un grupo de gestantes con preeclampsia grave. Rev Cubana Obstet Ginecol [serie en Internet]. 2009 Sep [citado 31 Jul 2013];35(3): Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138- 600X2009000300004&lng=es

  18. Sarmiento Portal Y, Crespo Campos A, Portal Miranda ME, Breto Rodríguez AG, Menéndez Humaran YR. Morbilidad y mortalidad en neonatos hijos de madres toxémicas. Rev Cubana Pediatr [revista en la Internet]. 2009 Sep [citado 31 Jul 2013];81(3): Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034- 75312009000300005&lng=es

  19. Sáez Cantero V, Pérez Hernández MT, Agüero Alfonso G, González García H, Alfonso Dávila A. Resultados perinatales relacionados con los trastornos hipertensivos del embarazo. Rev Cubana Obstet Ginecol. 2012 [citado 23 Ene 2012];38(1). Disponible en: http://bvs.sld.cu/revistas/gin/vol38_1_12 /gin05112.htm

  20. García Mirás R, Llera Valdés A, Pacheco Bermúdez AL, Delgado González MJ, González Sánchez A. Resultados maternos-perinatales de pacientes con preeclampsia. Rev Cubana Obstet Ginecol [revista en la Internet]. 2012 Dic [citado 31 Jul 2013];38(4):467-77. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138- 600X2012000400004&lng=es

  21. Pérez Hernández MT, Sáez CV, Agüero AG, González GH, Alfonso DA, Vilches LF. Incidencia y caracterización de los trastornos hipertensivos del embarazo. MEDISUR. 2011 [citado 21 Mar 2013];9(5):13-6. Disponible en: http://www.medisur.sld.cu/index.php/medisur/article/view/1709/6562

  22. Madan J, Chen M, Goodman E, Davis J, Allan W, Dammann O. Maternal obesity, gestational hypertension, and preterm delivery. The Journal of Maternal-Fetal and Neonatal Medicine. January 2010;23(1):82-8.

  23. Álvarez Ponce VA, Alonso Uría RM, Monteavaro Rodríguez M. Enfermedad hipertensiva en la gestante: Resultados de un servicio. Rev Cubana Med Gen Integr [serie en Internet]. 2008 Sep [citado 31 Jul 2013];24(3): Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864- 21252008000300009&lng=es

  24. Vatten LJ, Skjaerven R. Is pre-eclampsia more than one disease? BJOG. 2004;111:298-302.

  25. Parra M, San Martín A, Valdés E, Hasbún J, Quiroz L, Schepeler M, et al. Espectro clínico de la preeclampsia: estudio comparativo de sus diversos grados de severidad. Rev Chil Obstet Ginecol. 2007 [citado 2 Ago 2013];72(3). Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717- 75262007000300007&lng=es&nrm=iso

  26. Mora P, Gobernado JA, Pérez-Milán F, Cortés S. Estados hipertensivos del embarazo: resultados perinatales. Clínica e Investigación en Ginecología y Obstetricia. 2010 [citado 2 Ago 2013];37(2). Disponible en: http://zl.elsevier.es/es/revista/clinica-e-investigacion-ginecologia-obstetricia- 7/estados-hipertensivos-embarazo-resultados-perinatales-13148185-originales- 2010?bd=1

  27. Altunaga Palacio M, Lugones Botell M. Resultados perinatales en la preeclampsia con signos de gravedad. Rev Cubana Obstet Ginecol [serie en Internet]. 2011 Ago [citado 31 Jul 2013];37(2):147-53. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0138- 600X2011000200004&lng=es




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