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2014, Number 1

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Rev cubana med 2014; 53 (1)

Functional capacity and associated factors in patients with ankylosing spondylitis

Casas FN, Vidal RJ, Pérez CD, Castell PC, Gutiérrez RÁ

Language: Spanish
References: 27
Page: 50-60
PDF size: 77.10 Kb.


ABSTRACT

Introducción: the functional limitation and the inability are the mayor consequences for patients presenting Ankylosing Spondylitis, Different factors have been related to inability and its repercussion in the quality of life of these patients.
Objective: to assess the functional ability and to determine associated factors.
Method: a cross-sectional and descriptive study was conducted including 80 patients from the Protocol Consultation of Spondylo-artropathies seen from June, 2007 to July, 2009. Demographic, clinical, radiological, and laboratory data were obtained. The functional ability was assessed applying BASFI rate (Bath Ankylosing Spondylitis Functional Index) and the existing associations were determined.
Results: there was male sex predominance, (63.3 %). The mean age was 40,1 years. The disease onset period - older than 20 years old (73.8 %), had great BASFI (p=0 0.01); the occupation showed significant difference (56.14 %, p=0.04). The delay time from diagnosis, longer than 10 years, was significant (p=0.03). The cervical segment, sacroiliitis and BASDAI (Bath Ankylosing Spondylitis Activyt) showed a statistically significant BASFI increase (p=0.01), except the acute phase reactants and HLA-B27.
Conclusions: the functional ability is significantly associated with the disease onset age, diagnosis delay time, involvement of cervical segment, occupation, sacroiliitis, and the disease activity.


REFERENCES

  1. Ramírez-Sánchez JC, Miranda-Limón JM. Espondilitis anquilosante. Evaluación clínica y tratamiento. Rev Mex Reumat. 2005;20:143-55.

  2. Van der Heijde DM, Van der Linden SM, Bellamy N, Calin A, Dougados M, Khan MA. Which domains should be included in a core set for endpoints in ankylosing spondylitis? Introduction to the ankylosing spondylitis module of OMERACT IV. J Rheumatol. 1999;26:945-9.

  3. Ward MM, Weisman MH, Davis JC, Reveille JD. Risk factors for functional limitations in patients with long-standing ankylosing spondylitis. Arthritis Rheum. 2005;53:710-7.

  4. Falkenbach A, Franke A, Van der Linden S. Factors associated with body function and disability in patients with ankylosing spondylitis: a cross-sectional study. J Rheumatol. 2003;30:2186-92.

  5. Stone M, Warren RW, Bruckel J, Cooper D, Cortinovis D, Inman RD. Juvenile-onset ankylosing spondylitis is associated with worse functional outcomes than adult-onset ankylosing spondylitis. Arthritis Rheum. 2005;53:445-51.

  6. Ward MM. Predictors of the progression of functional disability in patients with ankylosing spondylitis. J Rheumatol. 2002;29:1420-5.

  7. Hamersma J, Cardon LR, Bradbury L. Is disease severity in ankylosing spondylitis genetically determined? ¿Es la gravedad de la enfermedad en la espondilitis anquilosante genéticamente determinada? Arthritis Rheum. 2001;44:1396-400.

  8. Van der Linden S, Valkenburg HA, Cats A. Evaluation of the NA. Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria. Arthritis Rheum. 1984;27(4):361-8.

  9. Gordeev VS, Maksymowych WP, Evers SM, Ament A, Schachna L, Boonen A. The role of contextual factors on health-related quality of life in Ankylosing Spondylitis. Ann Rheum Dis. 2009;9(1):108-12.

  10. Lee W, Reveille JD, Davis JC Jr, Learch TJ, Ward MM, Weisman MH. Are there gender differences in the severity of ankylosing spondylitis? Results from the PSOAS cohort. Ann Rheum Dis. 2007;66:633-8.

  11. Lee W, Reveille JD, Weisman MH. Women With Ankylosing Spondylitis: A Review. 2008;59(3):449-54.

  12. Sampaio-Barros PD, Bertolo MB, Kraemer MHS, Marques-Neto JF, Samara AM. Primary ankylosing spondylitis patterns of disease in a Brazilian population of 147patients. J Rheumatol. 2001;28:560-5.

  13. Lee W, Reveille JD, Davis JC Jr, Learch TJ, Ward MM, Weisman MH. Are there gender differences in the severity of ankylosing spondylitis? Results from the PSOAS cohort. Ann Rheum Dis. 2007;66:633-8.

  14. Londoño JD, Gozález LA, Ramírez LA, Santos MA, Santos AM, Romero CE, et al. Caracterización de las espondiloartropatías y determinación de factores de mal pronóstico en una población de pacientes colombianos. Revista Colombiana de Reumatología. 2005;12:195-207.

  15. Amor B, Santos RS, Nahal R, Listrat V, Dougados M. Predictive factors for the longterm outcome of spondyloarthropathies. J Rheumatol. 1994;21(10)1883-7.

  16. Brophy S, Mackay K, Al-Saidi A, Taylor G, Calin A. The natural history of ankylosing spondylitis as defined by radiological progression. J Rheumatol. 2002;29(6):1236-43.

  17. Gensler LS, Ward MM, Reveille JD, Learch TJ, Weisman MH, Davis JC Jr. Clinical, radiographic and functional differences between juvenile-onset and adultonset ankylosing spondylitis: results from the PSOAS cohort .Ann Rheum Dis. 2008;67:233-7.

  18. Sham LS, Chan KY, Li EK.The influence of illness and variables associated with functional limitations in Chinese patients with ankylosing spondylitis. J Rheumatol. 2007;34(5):1032-9.

  19. Ward MM, Reveille JD, Learch TJ, Davis JC Jr, Weisman MH. Impact of ankylosing spondylitis on work and family life: comparisons with the US population. Arthritis Rheum. 2008;59(4):497-503.

  20. Aggarwal R, Malaviya AN. Diagnosis delay in patients with ankylosing spondylitis: factors and outcomes an Indian perspective. Clin Rheumatol. 2009;28(3):327-31.

  21. Chandran V, O'shea FD, Schentag CT, Inman RD, Gdalman DD. Relationship Between Spinal Mobility and Radiographic Damage in Ankylosing Spondylitis and Psoriatic Spondylitis: A Comparative Analysis. J Rheumatol. 2007;34:2463-5.

  22. Gratacós Masmitjá J. Valoración de la actividad inflamatoria en la espondiloartritis anquilosante. Revista Española Reumatología. 2001;28(5):267-74.

  23. Uppal SS, Abraham M, Chowdhury RI, Kumari R, Pathan EM, Al Rashed A. Ankylosing spondylitis and undifferentiated spondyloarthritis in Kuwait: a comparison between Arabs and South Asians. Clin Rheumatol. 2006;25:219-24.

  24. Bellomio V, Berman A, Sueldo R, Molina MJ, Spindler A, Lucero E, et al. Registro Iberoamericano de Espondiloartritis (RESPONDIA): Argentina. Reumatol Clin. 2008;4(4):23-9.

  25. Huerta-Sil G, Casasola-Vargas JC, Londoño JD, Rivas-Ruíz R, Chavez J, Pacheco-Tena C, et al. Low grade radiographic sacroiliitis as prognostic factor in patients with undifferentiated spondyloarthritis fulfilling diagnostic criteria for ankylosing spondylitis throughout follow up. Rheumatology. 2004;43:85-8.

  26. Robertson LP, Davis MJ. A longitudinal study of disease activity and functional status in a hospital cohort of patients with ankylosing spondylitis. Rheumatology Oxford. 2004;43:1565-8.

  27. Pradeep DJ, Keat A, Gaffney KK, Gaffney K. Predicción de resultados en la espondilitis anquilosante. Rheumatology. 2008;47(7):942-45.




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