Macías-Delgado Y, Jiménez-Morales RM, Fundora DR, Gómez GAO, Sebrango RCR, Baldomir GRR

Language: Spanish
References: 15
Page:
PDF size: 135.39 Kb.

ABSTRACT

Introduction: cognitive fatigue in multiple sclerosis is addressed from different perspectives. In this study, it is defined as a decrease in performance during a cognitive task that requires a sustained mental effort.
Objective: assessing the association of cognitive fatigue with working memory and subjective fatigue in patients with multiple sclerosis.
Methods: the study included 20 patients with multiple sclerosis and healthy controls. The tools applied included the Paced Auditory Serial Addition Test, Wais-III subtest of inverted digits, Verbal Learning of 10 word sand, the Modified Scale of Fatigue Impact.
Results: patients showed a significant decline manifested in a 17%. The decline pattern in the control group corresponded to an 8,8%. Moderately significant differences were seen between both groups in regard to cognitive fatigue. Inpatients with multiple sclerosis, cognitive fatigue was associated with PASAT, but not with the Modified Scale of Fatigue Impact.
Conclusions: the study group showed objective measurements of cognitive fatigue. Cognitive fatigue was correlated with working memory, but not with subjective fatigue.

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