2014, Number 3
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Med Int Mex 2014; 30 (3)
A Brief Chronic of Metabolic Syndrome Definition
Córdova-Pluma VH, Castro-Martínez G, Rubio-Guerra A, Hegewisch ME
Language: Spanish
References: 132
Page: 312-328
PDF size: 531.80 Kb.
ABSTRACT
Since the first results from the Framingham Heart Study, the medical
community has gained interest in the risk factors for developing cardiovascular
diseases, because there is evidence of the coexistence of
conditions. The metabolic syndrome officially appeared in 1988, when
Gerald Reaven described “syndrome X” as the association of insulin resistance/
hyperinsulinemia (dysglycemia), dyslipidemia and hypertension
and his new entity got its name by WHO in 1999. In fact, the association
of this cardiovascular risk factors is known since ancient times and,
through history, has been given many names, such as “hypertensionhyperglycemia-
hyperuricemia syndrome”, “plurimetabolic syndrome”,
“diabetogenic obesity”, etc. Numerous international organizations have
sought to establish operational definitions, modifying the importance
and/or the cutoff values for certain variables. This paper describes the
historical background and scientific advances that allowed establishing
the syndrome, as well as the different operating variables and definitions
that have been used to diagnose it.
REFERENCES
Eknoyan G. A history of obesity, or how what was good became ugly and then bad. Adv Chronic Kidney Dis 2006;13:421-427.
Haslam D. A long look at obesity. Lancet 2010;376:85-86.
Burowski O. Eat, drink and be merry. The Mediterranean diet. Near Eastern Archeology 2004;67:96-107.
Dwivedi G, Dwivedi S. Sushruta–the ancient clinician and teacher par excellence-500 BC Indian. J Chest Dis Allied Sci 2007;49:243-244.
Tipton CM. Susruta of India, an unrecognized contributor to the history of exercise physiology. J Appl Physiol 2008;104:1553-1556.
Gilman SL. Fat boys in the cultural history of the west. 1a ed. University of Nebraska Press, 2004.
King KM, Rubin G. A history of diabetes: from antiquity to discovering insulin. Br J Nurs 2003;12:1091-1095.
Polonski KS. The past 200 years in diabetes. N Engl J Med 2012;367:1332-1340.
Bhattacharya S. Sushrutha-our proud heritage. Indian J Plast Surg 2009;42:223-225.
Lakhtakia R. The history of diabetes mellitus. SQU Medical J 2013;13:368-370.
Laios K, Karamanou M, Saradiki Z, Androutsos G. Aretaeus of Cappadocia and the first description of diabetes. Hormones 2012;11:109-113.
Best CH. The internal secretion of the pancreas. Canad Med Ass J 1962;87:1046-1051.
Himsworth HP. Diabetes mellitus: its differentiation into insulin-sensitive and insulin-insensitive types. Diabet Med 2011;28:1440-1444.
Esunge PM. From blood pressure to hypertension: the history of research. J R Soc Med 1991;84:621.
Kotchen TA. Historical trends and milestones in hypertension research: a model of the process of translational research. Hypertension 2011;58:522-538.
Postel-Vinay N. A century of arterial hypertension: 1896- 1996. 1a ed. Editorial Wiley, 1997.
http://www.framinghamheartstudy.org/about-fhs/history.php
Pineda CA. Síndrome metabólico: definición, historia, criterios. Colomb Med 2008;39:96-106.
Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988;37:1595-1607.
Haffner SM, Valdez RA, Hazuda HP, et al. Prospective analysis of the insulin-resistance syndrome (syndrome X). Diabetes 1992;41:715-722.
Hansen BC. Obesity, diabetes, and insulin resistance: implications from molecular biology, epidemiology, and experimental studies in humans and animals. Synopsis of the American Diabetes Association's, 29th Research Symposium and Satellite Conference of the 7th International Congress on Obesity, Boston, Massachusetts. Diabetes Care 1995;18:2-9.
Hansen BC. The metabolic syndrome X. Ann NY Acad Sci 1999;892:1-24.
Groop L. Genetics of the metabolic syndrome. Br J Nut 2000;83:39-48.
Meigs JB. Invited commentary: Insulin resistance syndrome? Syndrome X? Multiple metabolic syndrome? A syndrome at all? Factor analysis reveals patterns in the fabric of correlated metabolic risk factors. Am J Epidem 2000;152:908-911.
Isomaa B, Almigren P, Tuomi T. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care 2001;24:683-689.
Ford E, Giles W. A comparison of the prevalence of the metabolic syndrome using two proposed definitions. Diabetes Care 2003;26:575-581.
Haffner S, Taegtmeyer H. Epidemic obesity and the metabolic syndrome. Circulation 2003;108:1541-1545.
Kereiakes DJ, Willerson JT. Metabolic syndrome epidemic. Circulation 2003;108:1552-1553.
Lefèbvre PJ. The metabolic syndrome revisited. Int Congress Series 2003;1253:3-10.
Scheen AJ, Luyclx FH. Le síndrome métabolique; défintions et données, épidémiologoques. Rev Med Liege 2003;58:479-484.
Alberti G. Introduction to the metabolic syndrome. Eur Heart J Supplements 2005;7:3-5.
Miranda PJ, DeFronzo RA, Califf RM, Guyton JR. Metabolic syndrome: Definition, pathophysiology, and mechanisms. Am Heart J 2005;149:33-45.
Crepaldi G, Maggi S. The metabolic syndrome: historical context. Diabetes Voice 2006;5:8-10.
Gogia A, Agarwal L. Metabolic sydrome. Indian J Med Sci 2006;60:72-81.
Sarafidis P, Nilsson P. The metabolic syndrome: a glance at its history. J Hypertens 2006;24:621-626.
Balkau B, Valensi, Eschwege P, Slama G. A review of the metabolic syndrome. Diabetes Metab 2007;33:405-413.
Beaser RS, Levy P. A work in progress, but a useful construct. Circulation 2007;115:1812-1818.
Brietzke SA. Controversy in diagnosis and management of the metabolic syndrome. Med Clin N Am 2007;91:1041-1061.
Day C. Metabolic syndrome, or what you will: definitions and epidemiology. Diab Vasc Dis Res 2007;4:32-38.
Pi-Sunyer X. The metabolic syndrome: How to approach differing definitions. Med Clin N Am 2007;91:1025-1040.
Cornier et al. The metabolic syndrome. Endocrine Reviews 2008;29:777-822.
Braguinsky J. El síndrome metabólico, una secuencia patológica con punto de partida en la obesidad. Actualización en Nutrición 2009;10:9-10.
Griera Borrás JL, Contreras Gilbert J. Síndrome metabólico: ¿fin de la controversia? Rev Esp Obes 2010;8:69-74.
Gupta A, Gupta V. Metabolic syndrome: what are the risks for humans? Biosci Trends 2010;4:204-212.
Spellman, Chemitiganti. Metabolic syndrome: More questions than answers? JAOA 2010;110:18-22.
D’Adamo E, Santoro N, Caprio S. Metabolic syndrome in pediatrics: Old concepts revised, new concepts discussed. Pediatr Clin N Am 2011;58:1241-1255.
Gallagher EJ, LeRoith D, Karniel E. The metabolic syndrome– from insulin resistance to obesity and diabetes. Med Clin N Am 2011;95:855-873.
Kassi E, Pervanidou P, Kaltsas G, Chrousos G. Metabolic syndrome: definitions and controversies. BMC Med 2011:9-48.
Oda E. Metabolic syndrome: its history, mechanisms, and limitations. Acta Diabetol 2012;49:89-95.
Hatchepsut BL. The female pharaoh: Joyce Tyldesley. Domes 1997;6:68-71.
Enzi G, Busetto L, Inelmen EM, Coin A, Sergi G. Historical perspective: visceral obesity and related comorbidity. In: Joannes Baptista. Morgagni's ‘De sedibus et causis morborum per anatomen indagata’. Int J Obes Relat Metab Disord 2003;27:534-535.
Gries FA, Liebermeister H. The metabolic syndrome. Exp Clin Endocrinol Diabetes 2003;111:299.
Milici N. A short history of the metabolic syndrome definitions. Proc Rom Acad Series B 2010;1:13-20.
Hitzenberger K, Richter-Quittner M. Ein Beitrag zum Stoffwechsel bei der vaskulären Hypertonie. Wiener Arch Innere Med 1921;2:189-216.
Hitzenberger K. Über den Blutdruck bei Diabetes mellitus. Wiener Arch Innere Med 1921;2:461-466.
Kylin E. Hypertonie and Zuckerkrankheit. Zentralblatt für Innere Medizin 1921;42:873-877.
Marañón G: Über Hypertonie und Zuckerkrankheit. Zentralblatt für Innere Medizin 1922;43:169-176.
Kylin E. Studien über das Hypertonie-Hyperglykämie- Hyperurikämie Syndrom. Zentralblatt für Innere Medizin 1923;44:105-112.
Pi Suñer. Las glucodistrofias. Anales de la Real Academia de Medicina y Cirugía de Barcelona 1930:178-185.
Vague J. La differentiation sexuelle. Facteur determinant des formes de l’obesité. Presse Med 1947;55:339-341.
Vague, J. The degree of masculine differentiation of obesities: a factor determining predisposition to diabetes, atherosclerosis, gout, and uric calculous disease. Am J Clin Nutr 1956;4:20-34.
Albrink MJ, Meigs JW. Interrelationship between skinfold thickness, serum lipids and blood sugar in normal men. Am J Clin Nutr 1964;15:255-261.
Welborn TA et al. Serum-insulin in essential hypertension and in peripheral vascular disease. Lancet 1966;1:1336- 1337.
Reaven G, Calciano A, Cody R, Lucas C, Millar R. Carbohydrate intolerant and hyperlipemia in patients with myocardial infarction without known diabetes mellitus. J Clin Endocrinol Metab 1963;23:1013-1023.
Randle PJ, Garland PB, Hales CN, Neswholme EA. The glucose–fatty acid cycle: its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet 1963;1:785-789.
Camus JP. Goutte, diabete, hyperlipemie: un trisyndrome metabolique. Rev Rhum 1966;33:10-15.
Avogaro P, Crepaldi G. Essential hyperlipidemia, obesity and diabetes. Diabetologia 1965;1:137.
Avogaro P, Crepaldi G. Plurimetabolic syndrome. Acta Diabetol Lat 1967;4:572-580.
Mehnert H, Kuhlmann H. Hypertonie und diabetes mellitus. Dtsch Med J 1968;19:567-571.
Hanefeld M. Untersuchungen über wechselbeziehungen zwischen lipidstoffwechsel und leberkrankheiten. Dresden: Habilitation. Medizinische Akademie 1973.
Welborn, Wearne K. Coronary heart disease incidence and cardiovascular mortality in Busselton with reference to glucose and insulin concentrations. Diabetes Care 1979;2:154-160.
Pyörälä K. Relationship of glucose tolerance and plasma insulin to the incidence of coronary heart disease: results from two population studies in Finland. Diabetes Care 1979;2:131-141.
Ruderman NB, Schneider SH, Berchtold P. The “metabolically- obese”, normal-weight individual. Am J Clin Nutr 1981;34:1617-1621.
Kissebah AH, Vydelingum N, Murray R, et al. Relation of body fat distribution to metabolic complications of obesity. J Clin Endocrinol Metab 1982;54:254-260.
Modan M, Halkin H, Almog S, et al. Hyperinsulinemia. A link between hypertension, obesity, and glucose intolerance. J Clin Invest 1985;75:809-817.
Modan M, Halkin H, Karasik A, Lusky A. Elevated serum uric acid–a facet of hyperinsulinaemia. Diabetologia 1987;30:713-718.
Landsberg L. Diet, obesity and hypertension: a hypothesis involving insulin, the sympathetic nervous system, and adaptive thermogenesis. Q J Med 1986;6:1081-1090.
Fujioka S, Matsuzawa Y, Tokunaga K, Tarui S. Contribution of intra-abdominal fat accumulation to the impairment of glucose and lipid metabolism in human obesity. Metabolism 1987;36:54-59.
Ferrannini E, Buzzigoli G, Bonadonna R, et al. Insulin resistance in essential hypertension. N Engl J Med 1987;317:350-357.
Hanefeld M, Leonhardt W. Das metabolische syndrome. Dt Gesundh Wesen 1981;36:545-551.
Vague J, Vague P, Jubelin J. A 35-year follow up of diabetogenic obesity. Int J Obes 1987;11:38.
Kaplan NM. The deadly quartet: upper body adiposity, glucose intolerance, hypertriglyceridaemia and hypertension. Arch Intern Med 1989;149:1514-1520.
Serjeantson SW, Zimmet P. Genetics of non-insulin dependent diabetes mellitus in 1990. Baillieres Clin Endocrinol Metab 1991;5:477-493.
DeFronzo RA, Ferrannini E. Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia and atherosclerotic cardiovascular disease. Diabetes Care 1991;14:173-194.
Zimmet PZ. Kelly West Lecture 1991. Challenges in diabetes epidemiology: from West to the rest. Diabetes Care 1992;15:232-252.
Björntrop P. Abdominal obesity and the metabolic syndrome. Ann Med 1992;24:465-468.
Desprès JP. Abdominal obesity as important component of insulin-resistance syndrome. Nutrition 1993;9:452-459.
Yudkin JS. Microalbuminuria: a genetic link between diabetes and cardiovascular disease? Ann Med 1992;6:517-522.
Florez, H, Ryder E, Campos G, et al. Women relatives of Hispanic patients with type 2 diabetes are more prone to exhibit metabolic disturbances. Invest Clin 1999;40:127- 142.
Shafrir, E. Development and consequences of insulin resistance: lessons from animals with hyperinsulinaemia. Diabetes Metab 1996;22:122-131.
Matsuzawa YM. Pathophysiology and molecular mechanism of visceral fat syndrome: the Japanese experience. Diabetes Metab Rev 1997;13:3-13.
World Health Organization: Definition, diagnosis, and classification of diabetes mellitus and its complications: Report of a WHO consultation. Geneva, World Health Organization 1999.
Cheng TO. The metabolic syndrome, formerly called metabolic “syndrome X”. Am J Cardiol 2004;94:148-149.
Kemp HG. Left ventricular function in patients with anginal syndrome and normal coronary arteriograms. Am J Cardiol 1973;32:375-376.
Stern MP. The insulin resistance syndrome. In: Alberti KGMM, Zimmet P, DeFronzo RA, editors. International textbook of diabetes mellitus. 2nd ed. Chichester: John Wiley, 1997;255-283.
European Arterial Risk Policy Group on behalf of the International Diabetes Federation European Region. A strategy for arterial risk assessment and management in type 2 (non–insulin–dependent) diabetes mellitus. Diabet Med 1997;14:611-621.
Mykkänen L, Kuusisto J, Pyörälä K, Laakso M. Cardiovascular disease risk factors as predictors of Type 2 (noninsulin- dependent) diabetes mellitus in elderly subjects. Diabetologia 1993;36:553-559.
Eriksson KF, Lindegärde F. Prevention of Type 2 (non-insulindependent) diabetes mellitus by diet and physical exercise. Diabetologia 1991;34:891-898.
World Health Organization. Diabetes mellitus: Report of a WHO Study Group. Geneva: WHO 1985. Technical Report Series 727.
Balkau B, Charles MA. Comment on the provisional report from the WHO consultation. European Group for the Study of Insulin Resistance (EGIR). Diabet Med 1999;16:442-443.
Laakso, M. How good a marker is insulin level for insulin resistance? Am J Epidemiol 1993;137:959-965.
Wood D, De Backer G, Faergeman O, Graham I, et al. Prevention of coronary heart disease in clinical practice. Summary of the recommendations of the second joint task force of European and other societies on coronary prevention. J Hypertens 1998;16:1407-1414.
Lean ME, Han TS, Seidell JC. Impairment of health and quality of life in people with large waist circumference. Lancet 1998;351:863-866.
Expert panel on the detection, evaluation, and treatment of high blood cholesterol in adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult treatment panel III). JAMA 2001;285:2486-2497.
Third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). Final report. Circulation 2002;106:3143-3421.
Grundy SM, Brewer HB Jr, Cleeman JI, Smith SC Jr, Lenfant C. Definition of metabolic syndrome. Report of the National Heart, Lung, and Blood Institute/American Heart Association Conference on scientific issues related to definition. Circulation 2004;109:433-438.
Einhorn D, Reaven GM, Cobin RH, Ford E, et al. American College of Endocrinology position statement on the insulin resistance syndrome. Endocr Pract 2003;9:236-252.
Carr A, Workman C, Carey D, et al. No effect of rosiglitazone for treatment of HIV-1 lipoatrophy: randomised, double-blind, placebo controlled trial. Lancet 2004;363:429-438.
The DECODE Study Group, on behalf of the European Diabetes Epidemiology Group. Is the current definition for diabetes relevant to mortality risk from all causes and cardiovascular and noncardiovascular diseases? Diabetes Care 2003;26:688-696.
International Diabetes Federation. The IDF consensus worldwide definition of the metabolic syndrome. Disponible en http://www.idf.org/webcast/pdf/IDF_Backgrounder_ 1.pdf
Dunstan DW, Zimmet PZ, Welborn TA, et al. The rising prevalence of diabetes and impaired glucose tolerance. The Australian Diabetes, Obesity and Lifestyle Study. Diabetes Care 2002;25:829-834.
Alberti KG, Zimmet P, Shaw J. IDF Epidemiology Task Force Consensus Group. The metabolic syndrome: a new worldwide definition. Lancet 2005;366:1059-1062.
Grundy SM, Cleeman JI, Daniels SR, Donato KA, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement [published corrections appear in Circulation. 2005; 112:e297 and Circulation. 2005;112:e298]. Circulation 2005;112:2735-2752.
Kahn R, Buse J, Ferrannini E, Stern M. The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2005:28:2289-2304.
International Diabetes Federation. Rationale for new IDF worldwide definition of the metabolic syndrome. http:// www.idf.org/webcast/pdf/IDF_Backgrounder_2.pdf
Alberti KGMM, Zimmet P, Shaw J. Metabolic syndrome –a new world-wide definition. A consensus statement from the international diabetes federation. Diabet Med 2006;23:469-480.
Kim SH, Reaven GM. The metabolic syndrome: one step forward, two steps back. Diabetes Vasc Dis Res 2004;1:68- 76.
Reaven G. The metabolic syndrome or the insulin resistance syndrome? Different names, different concepts, and different goals. Endocrinol Metab Clin North Am 2004;33:283- 303.
Reaven GM. The metabolic syndrome: requiescat in pace. Clin Chem 2005;51:931-938.
Reaven GM. Counterpoint: Just being alive is not good enough. Clin Chem 2005;51:1354-1357.
Reaven GM. The metabolic syndrome: is this diagnosis necessary? Am J Clin Nutr 2006;83:1237-1247.
Klein S, Allison DB, Heymsfield SB, et al. Waist circumference and cardiometabolic risk: a consensus statement from Shaping America’s Health: Association for Weight Management and Obesity Prevention, NAASO, The Obesity Society, the American Society for Nutrition, and the American Diabetes Association. Diabetes Care 2007;30:1647-1652.
Alberti KGMM, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome. A joint interim statement of the international diabetes federation task force on epidemiology and prevention, National Heart, Lung, and Blood Institute, American Heart Association, World Heart Federation, International Atherosclerosis Society, and International Association for the Study of Obesity. Circulation 2009;120:1640-1645.
National Institutes of Health. Clinical guidelines on the identification, evaluation, and treatment of overweight and obesity in adults: the evidence report [published correction appears in Obes Res 1998;6:464]. Obes Res 1998;6:51-209.
Simmons RK, Alberti KG, Gale EA, et al. The metabolic syndrome: useful concept or clinical tool? Report of a WHO Expert Consultation. Diabetologia 2010;53:600-605.
http://www.cenavece.salud.gob.mx/programas/interior/ adulto/descargas/pdf/NOM015DM.pdf
Westwater JO, Fainer D. Liver impairment in the obese. Gastroenterology 1958;34:686-693.
Ludwig J, Viggiano TR, McGill DB, Oh BJ. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980;55:434-438.
Marceau P, Biron S, Hould FS, et al. Liver pathology and the metabolic syndrome X in severe obesity. J Clin Endocrinol Metab 1999;84:1513-1517.
Cortez-Pinto H, Camilo ME, Baptista A, et al. Non-alcoholic fatty liver: another feature of the metabolic syndrome? Clin Nutr 1999;18:353-358.
Marchesini G. Nonalcoholic fatty liver disease: A feature of the metabolic syndrome. Diabetes 2001;50:1844-1850.
Kotronen A, Yki-Järvinen H. Fatty liver: a novel component of the metabolic syndrome. Arterioscler Thromb Vasc Biol 2008;28:27-38.