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2014, Number 1

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Evid Med Invest Salud 2014; 7 (1)

Effect of blood glucose control in septic patients in the Intensive Care Unit

Aguilar-Gutiérrez Z, Revilla RE, Olvera SV, Chávez MA, Ramírez CJB, Ruiz OMR

Language: Spanish
References: 18
Page: 19-23
PDF size: 274.53 Kb.


ABSTRACT

Background: The metabolic response to trauma is comprised of various mechanisms of counter looking restore homeostasis immediately; one of which is the action of hormones to keep blood sugar under stress by conditioning hyperglycemia which in turn has been associated with higher rates of infection and mortality in critically ill septic patients. Objective: To determine the effect of strict glycemic control on the development and survival of critically ill septic patients. Material and methods: Retrospective, observational and analytical study. Results: We included 23 patients with complete clinical records: 12 men (52%) and 11 women (48%), average age in both genders: 40. They were grouped as patients without strict control of blood glucose (CNE) (blood glucose equal to or greater than 121 mg%) strict control of blood glucose (CE) (average blood glucose between 90-120 mg%) and control. The EC group: 7 (30%) males and 6 (26%) women versus CNE: 5 (22%) males and 6 (26%) women (OR = 1.17; p = 0.85), admission APACHE score: 21 ± 6 CE versus 25 ± 5 CNE; days ICU long stay: 14 ± 9 CE versus 13 ± 8 CNE; central average blood glucose 110 ± 7 mg% versus EC 137 ± 9 mg% CNE. Risk of died 2 fold in CNE (p = 0.43). Conclusion: Strict blood glucose control in critically ill septic patients improves their development and survival.


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