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Anales de Otorrinolaringología Mexicana

2014, Number 2

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Otorrinolaringología 2014; 59 (2)

Recurrent Respiratory Papillomatosis, Results of the Treatment with CO2 Laser in a Reference Center; Experience of Six Years

Soto-Posada MI, Tamez-Velarde M, Domínguez-Sosa FR

Language: Spanish
References: 17
Page: 92-101
PDF size: 282.26 Kb.


ABSTRACT

Background: Recurrent respiratory papillomatosis (RRP) has been little studied in Mexico. Data on the incidence, course and treatment outcomes are scarce. We studied the population with this disease in a referral hospital to determine the epidemiology and the results obtained with CO2 laser treatment and compared the results with those of the international literature.
Objective: To determine the response to treatment and recurrencies of respiratory papillomatosis in patients treated with direct laryngoscopy and resection with laser CO2.
Patients and method: A retrospective cohort study was done at Hospital Central Sur de Alta Especialidad, Pemex, Mexico City, from January 1st 2004 to May 31st 2010. The cohort consisted of patients with a histopathologic diagnosis of recurrent respiratory papillomatosis by direct laryngoscopy and treated with CO2 laser resection that will have a minimum of six months follow-up and had a full file. We obtained demographic and clinical condition pre, trans, and postoperative follow-up for each patient. The study included 20 patients with recurrent respiratory papillomatosis, 12 (60%) men and 8 (40%) women.
Results: Nine patients in remission, four patients in clearance, two patients cured and five patients with recurrences. Comparing with the international literature there were variations in the epidemiology due to the type of population of the referral center.
Conclusions: The results obtained with the CO2 laser were similar to those reported in the international literature regarding fewer recurrences, less bleeding, less surgical time and similar late complications, confirming that resection must be limited to prevent stenosis. We suggest to promote training of Mexican otolaryngologists to extend the use of this surgical technique in patients with recurrent respiratory papillomatosis.


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