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2014, Number 1

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Revista Habanera de Ciencias Médicas 2014; 13 (1)

Covalent modifications of proteins. A qualitative higher level of molecular information

Hernández FRA

Language: Spanish
References: 27
Page: 20-35
PDF size: 370.71 Kb.


ABSTRACT

Introduction: Molecular information is an essential property of biomacromolecules, especially proteins and nucleic acids. This property allows carrying out specific functions. It derives from variability of macromolecules components.
Objetive: To prove that covalent modification of proteins represents a new and higher level of molecular information.
Method: Papers published during the last five years in national and international journals were analyzed. These articles are available in HINARI, PubMed, and Perii databases and were localized through www.infomed.sld.cu.
Main text: First, the mechanism and features of covalent modifications of protein are presented. Next, the principal effects on protein functions and properties are analyzed.
Conclusions: We conclude that covalent modification of proteins represents a new and higher level of molecular information.


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