2014, Number 1
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Anales de Radiología México 2014; 13 (1)
Crohn’s disease: evaluation with Aceptado: 13 de julio de 2013 magnetic resonance enterography
Romero – Sánchez GT, Díaz – Zamudio M, Yamamoto - Furusho JK, Romero – Trejo C, Téliz – Meneses MA, Chapa – Ibargüengoitia M, Montante - Montes de Oca D, Vázquez – Lamadrid J
Language: Spanish
References: 26
Page: 59-72
PDF size: 673.92 Kb.
ABSTRACT
Introduction. Crohn’s disease is a chronic inflammatory condition that
may affect any segment of the digestive tract, from the mouth to the
anus, and belongs to the group of inflammatory intestinal diseases (IID).
Diagnosis is based on clinical, biochemical, endoscopic, radiological,
and histopathological correlation. Magnetic resonance enterography is a
non-invasive diagnostic method that does not use ionizing radiation and
complements the diagnosis of Crohn’s disease; it provides information on the extent, degree of inflammation, and possible complications. It
plays an important role in classification and surgical planning.
Objective. Describe findings by magnetic resonance enterography in
Crohn’s disease and conduct a review of the specialized literature.
Material and methods. A cross-sectional, descriptive study was conducted.
All patients with Crohn’s disease who were admitted for consultation
at the Salvador Zubiran National Institute of Medical Science
and Nutrition Department of Gastroenterology Inflammatory Intestinal
Disease Clinic, in the period October 2011 through April 2012 were
included. All the patients underwent clinical evaluation, laboratory
studies, and magnetic resonance enterography.
Results. Magnetic resonance enterography found signs of active disease
in 46.6% of the patients. The most common manifestations were wall
thickening (80%), alteration of mucosal pattern (73%), and reinforcement
of the wall (60%). The segment most commonly involved was
the ileum (60%).
Conclusions. Magnetic resonance may provide anatomic details,
functional observations, and information in real time without the use
of ionizing radiation in evaluation of Crohn’s disease.
REFERENCES
Baumgart DC, Sandborn WJ. Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 2007;369:1641-57.
Barahona-Garrido J, Yamamoto-Furusho JK, et al. IBD, inflammatory bowel disease; Rev Gastroenterol Mex 2009;74:230–7.
Sinha R, Murphy P, Hawker P, et al. Role of MRI in Crohn’s disease. Clin Radiol 2009;64:341–52.
Sostegni R, Daperno M, Scaglione N, et al. Rewiew article: Crohn ́s disease: monitoring disease activity. Aliment Pharmacol Ther 2003;17:11-7.
Hugh JF. Use of the Crohn´s disease activity index in clinical trials of biological agents. World J Gastroenterol 2008;14:4127-30.
Jaffe TA, Nelson RC, Johnson GA, et al. Optimization of multiplanar reformations from isotropic data sets acquired with 16-detector row helical CT scanner. Radiology 2006;238:292–9.
Groves AM, Owen KE, Courtney HM, et al. 16-detector multislice CT: dosimetry estimation by TLD measurement compared with Monte Carlo simulation. Br J Radiol 2004;77:662–5.
Hurwitz LM,Yoshizumi T, Reiman RE, et al. Radiation dose to the fetus from body MDCT during early gestation. AJR Am J Roentgenol 2006;186:871–6.
Jaffe TA, Gaca AM, Delaney S, et al. Radiation doses from small-bowel follow through and abdominopelvic MDCT in Crohn’s disease. AJR Am J Roentgenol 2007;189:1015–22.
Dixon AK, Dendy P. Spiral CT: how much does radiation dose matter? Lancet 1998;352:1082–3.
Leyendecker JR, Bloomfeld RS, DiSantis DJ, et al. MR Enterography in the Management of Patients with Crohn Disease. Radio Graphics 2009;29:1827-46.
Horsthuis K, Stokkers PC, Stoker J. Detection of inflammatory bowel disease: diagnostic performance of cross-sectional imaging modalities. Abdom Imaging 2008;33:407–16.
Sinha R, Verma R, Verma S, et al. MR enterography of Crohn disease. Part 1. Rationale, technique, and pitfalls. AJR 2011;197:76–9.
Herrmann KA, Zech CJ, Michaely HJ, et al. Comprehensive magnetic resonance imaging of the small and large bowel using intraluminal dual contrast technique with iron oxide solution and water in magnetic resonance enteroclysis. Invest Radiol 2005;40:621–9.
Ajaj W, Lauenstein TC, Langhorst J, et al. Small bowel hydro-MR imaging for optimized ileocecal distension in Crohn’s disease: should an additional rectal enema filling be performed? J Magn Reson Imaging 2005;22:92–100.
Young BM, Fletcher JG, Booya F, et al. Head-to-head comparison of oral contrast agents for cross-sectional enterography: small bowel distention, timing, and side effects. J Comput Assist Tomogr 2008;32:32–8.
Yacoub JH, Obara P, Oto A. Evolving role of MRI in Crohn’s disease. J Magn Reson Imaging 2013;37(6):1277-89.
Maccioni F, Bruni A, Viscido A, et al. MR imaging in patients with Crohn disease: value of T2- versus T1-weighted gadolinium- enhanced MR sequences with use of an oral superparamagnetic contrast agent. Radiology 2006;238:517–30.
Udayasankar UK, Martin D, Lauenstein T, et al. Role of spectral presaturation attenuated inversion- recovery fat-suppressed T2-weighted MR imaging in active inflammatory bowel disease. J Magn Reson Imaging 2008;28:1133–40.
Maglinte DD, Gourtsoyiannis N, Rex D, et al. Classification of small bowel. Crohn’s subtypes based on multimodality imaging. Radiol Clin North Am 2003;41:285-303.
Rodriguez P, Anguita G, Matute F, et al. Imaging atlas of Crohn’s disease: MR-Enterography. Electronic Presentation Online System (EPOS TM) 2012 [Internet], Disponible en: http://posterng.netkey.at/esr/online_viewing/index.php. 12-12-13
Sauer CG, Middleton JP, Alazraki A, et al. Comparison of magnetic resonance enterography with endoscopy, histopathology, and laboratoryevaluation in pediatric Crohn disease. J PediatrGastroenterolNutr. 2012;55:178-84.
Girometti R, Zuiani C, Toso F, et al. MRI scoring system includ- ing dynamic motility evaluation in assessing the activity of Crohn’s disease of the terminal ileum. Acad Radiol 2008;15:153–64.
Sempere GAJ, Martinez Sanjuan V, Medina Chulia E, et al. MRI evaluation of inflammatory activity in Crohn’s disease. AJR Am J Roentgenol 2005;184:1829–35.
Savoye-Collet C, Savoye G, Koning E, Dacher JN, Lerebours E. Fistulizing perianal Crohn’s disease: contrast-enhanced mag- netic resonance imaging assessment at 1 year on maintenance anti-TNF-alpha therapy. Inflamm Bowel Dis 2011;17:1751–8.
Ng SC, Plamondon S, Gupta A, et al. Prospective evaluation of anti-tumor necrosis factor therapy guided by magnetic resonance imaging for Crohn’s perineal fistulas. Am J Gastroenterol 2009;104:2973–86.