Halabe CJ, Hoyo UI

Language: Spanish
References: 10
Page: 106-107
PDF size: 198.70 Kb.

ABSTRACT

Recurrent clostridium difficile infection (CDI) is a challenge for infectious disease specialists. A third of first recurrences will fail antibiotic therapy1. Several mechanisms have been proposed to explain this, such as persistence of spores, inadequate antibody response, and altered gut microbiota2-4. Standard recommendations for CDI treatment include metronidazole and vancomycin5. Fecal transplant has proven to be an effective therapy for recurrent CDI. Infusion of stools can be administered to the upper or lower gastrointestinal tract during an endoscopic procedure or using nasogastric/duodenal or rectal tubes6-9. Elderly persons have an increased incidence of recurrent infection and have a higher mortality rate10. We propose a home-based delivery method using a 5 ml syringe for intrarectal infusion of stools.

REFERENCES

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