2014, Number 1
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Gac Med Mex 2014; 150 (1)
A 35-Year report of the study of group on gastrointestinal cancer in Mexico City: variations in frequency of different digestive tract neoplasms among different socioeconomic statuses
Villalobos PJJ, Bourlon MT, Loaeza CA, Torres VG
Language: Spanish
References: 37
Page: 49-57
PDF size: 247.81 Kb.
ABSTRACT
Background: Since the middle of the last century, North America and occidental countries have reported variations in
the frequency of gastrointestinal neoplasms. Several environmental factors, mainly nutritional and dietary exposure, as
well as habits have contributed to these changes. We have documented these changes in Mexico during the last
35 years.
Aims: To define the epidemiologic changes of gastrointestinal neoplasms during the last three decades in
our population.
Methods: We summarized the evidence of an observational study, registering the frequency of different
gastrointestinal malignancies from four institutions of socioeconomically different populations in Mexico City during 35 years. The Mexican National Academy of Medicine supported this effort. During this period, two nutritional surveys
took place, letting us define the relationship between dietary changes and cancer occurrence.
Results: Replacement of
gastric cancer by colorectal cancer as the leading gastrointestinal malignancy. Relationship between cancer and diet changes.
Increase of esophageal adenocarcinoma in relation to epidermoid carcinoma secondary to gastroesophageal reflux and
Barrett’s esophagus rising incidence. Gall bladder cancer had a high frequency in one institution, probably related to genetic
and racial factors.
Conclusions: This epidemiologic data should lead us to implement sanitary measures for the prevention,
early diagnosis, and appropriate treatment of gastrointestinal neoplasms.
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