2014, Number 1
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Rev Med Inst Mex Seguro Soc 2014; 52 (1)
Current position about the use of estrogen therapy in women during the climacteric period
Zárate A, Hernández-Valencia M, Saucedo R, Basurto L, Manuel AL
Language: Spanish
References: 20
Page: 66-69
PDF size: 49.23 Kb.
ABSTRACT
The hormonal therapy should begin only in order to control the symptoms
of the climacteric in women; its use is not recommended to prevent other
types of affections associated to the posmenopause, because, despite
some other recognizable benefi ts have been described, many of them
have not been demonstrated. Before beginning the treatment of hormonal
therapy, it is recommended to analyze the risk factors for heart attack or
other cardiovascular diseases, and also estimate risk for osteoporosis
and breast cancer. Diverse presentations and ways of administration of
the hormonal therapy have been used, with which outcome have been
obtained that vary in connection with predominant symptoms. Recently,
the introduction of the concept based on the combined use of an estrogen
associated to selective estrogen receptor modulator (SERM), the
tissue selective estrogen complex (TSEC), allows a better clinical profi le
for the patient. With this combination it is obtained endometrial protection
and positive action about the changes that the menopause produces.
The decision to continue the hormonal therapy should be individualized,
based on the severity of the symptoms and recurrence, considering the
risk-benefi t foreseen with the woman in the clinic.
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