2013, Number 2
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Rev Mex Periodontol 2013; 4 (2)
Involvement of Interleukin-17 in chronic and aggressive periodontitis
Herrera MMC, Guerrero VC, Martínez RV
Language: Spanish
References: 30
Page: 73-77
PDF size: 348.65 Kb.
ABSTRACT
Periodontal disease (PD) is one of the most common chronic infectious diseases in humans. The clinical features of chronic and aggressive periodontitis include attachment loss, alveolar bone loss, periodontal pockets and gingival inflammation. Both virulence factors of periodontal bacteria and the immune response against them are involved in the tissue destruction observed in periodontitis.
Cytokines are mediators of the immune response that plays an important role in the pathogenesis of periodontal disease. This article is a review that focuses on the role of IL-17 on bone loss in both chronic and aggressive periodontitis, because in recent years have described the involvement of this cytokine in other chronic degenerative diseases like arthritis rheumatoid where one of the major conditions is bone loss
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