2013, Number 2
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Rev Endocrinol Nutr 2013; 21 (2)
Building a proper diet based on the Latin genome
Ojeda-Granados C, Panduro A, Ramos-López O, Román S
Language: Spanish
References: 46
Page: 84-92
PDF size: 511.47 Kb.
ABSTRACT
At the genomic level, people are 99% the same. The small fraction that varies among people may be a single nucleotide polymorphism in the Deoxyribonucleic acid (DNA) sequence that makes each person unique. Knowing about genetic polymorphisms and ancestral informative markers within a population leads to understand about their history. It acknowledges the origin of the population’s genetic admixture, as well as the environment, lifestyle or diet in which they have lived throughout their past and how genetic polymorphisms were favored by natural selection. Latin-Americans are a wide cultural and genetically diverse population. Within these groups, lay the highest prevalence rates of obesity and other chronic diseases, such as type 2 diabetes and cardiovascular diseases. Such diseases are the result of a gene-environmental imbalance, in which lifestyle and nutrition play an important role. In this review, a proposal for nutritional intervention for people in the Latin-American region, included Mexico is presented. It is an initial strategy that considers the overall genomic and environmental features of the population and subgroups for the prevention and management of chronic diseases.
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