2013, Number 2
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Rev Hematol Mex 2013; 14 (2)
CHOP successful response in a patient with multicentric Castleman’s disease variety plasmacytic
Ron-Guerrero CS, Ron-Magaña AL
Language: Spanish
References: 22
Page: 96-100
PDF size: 287.91 Kb.
ABSTRACT
Castleman’s disease is a rare condition. With poor prognosis in untreated plasma cell variety, characterized by multiorgan and multisystem failure. It is difficult to diagnose when it presents atypically and be cause it is simulating many neoplastic diseases of origin lymphatic and no lymphatic. We describe a case of a 47 year old female with advanced multicentric Castleman disease with aggressive presentation, recurrent ascites, poor infiltration lymph nodes, bone marrow lymphoplasmacytic infiltration and very high alkaline phosphatase. The diagnosis was delayed and the disease advanced, however the response to treatment with CHOP has been successful. The atypical clinical presentation and good response to treatment of this case motivating this report.
REFERENCES
Castleman B, et al. Case X40011. Hyperplasia mediastinal lymph node. New Engl J Med 1954;250:26-30.
Flendrig JA, Schillings PHM. Benign giant lymphoma: The clinical signs and symptoms and the morphological aspects. Folia Med 1969;12:119-120.
Keller AR, Hochholzer L, Castleman B. Hyaline-vascular and plasma-cell types of the giant lymph node hyperplasia of the mediastinum and other locations. Cancer 1972;29:670-683.
Gaba AR, Stein RS, Sweet DL, et al. Multicentric giant lymph node hyperplasia. Am J Clin Pathol 1978;69:86-90.
Kojima M, Nakamura N, Tsukamoto N, Otuski Y, Shimizu K, Kobayashi S, Kobayashi H, Murase T, Masawa N, Kashimura M, Nakamura S. Clinical implications of idiopathic multicentric Castleman´s disease among Japanese: a report of 28 cases. Int J Surg Pathol 2008;391-398.
Abdou S, Salib H. An extra ordinary response of Castleman´s Disease to rituximab. Blood 2004;104:49b. Abstract 3849.
Pavlidis NA, Briassoulis E, Klouvas G, et al. Is interferona an active agent in Castleman´s disease? Ann Oncol 1992;3:85-86.
Lee FC, Merchant SH. Alleviaton of systemic manifestations of multicentric Castleman´s disease by thalidomide. Am J Hematol 2003;73:48-53.
Repetto L, Jaiprakash MP, Selby PJ, et al. Aggressive angiofollicular lymph node hyperplasia (Castleman´s disease) treated with high dose melphalan and autologous bone marrow transplantation. Hematol Oncol 1986;4:213-217.
Lerza R, Castello G, Truini M, et al. Splenectomy induced complete remission in a patient with multicentric Castleman´s disease and autoimmune hemolytic anemia. Ann Hematol 1999;78:193-196.
Dispenzieri A, Pittaluga S, Facchetti F, Fevillard J, Jaffe ES. Diagnosis and management of disorders that can mimic lymphoma. In: James O Armitage, Peter M. Mauch, Nancy Lee Harris, Bertrand Cpiffier, Riccardo Dalla-Favera eds. Non-Hodgkin Lymphomas. Philadelphia: Lippincott Wlliams & Wilkins, 2010;557-564.
Kreft A, Weber A, Springer E, Hess G, Kirkpatrick CJ. Bone marrow findings in multicentric Castleman Disease in HIVnegative patients. Am J Surg Pathol 2007;31:398-402.
Dispenzieri A. Castleman disease. Cancer Treat Res 2008;142:293-330.
McCarty MJ, Vukelja SJ, Bank PM, et al. Angiofollicular lymph node hyperplasia (Castleman´s disease). Cancer Treat Rev 1995;21:291-330.
Lopéz-Krauletz S, Nellen-Hummel H, Jacobo-Rubalcava A, Iparraguirre-Palomeque V, Flores-Figueroa F, Ayala- Hernández I, Halabe-Cherem J. A 42 years old woman with ascitis and presence of generalized linfadenopathy. Gac Méd Méx 2005;141.
Tae JK, Joon KH, Young HK, Tae KK, Byung IC. Castleman Disease of the Abdomen: Imaging Spectrum and Clinicopathologic Correlations. Journal of Computer Assisted Tomography 2001;25:207-214.
Izuchukwu SI, Tourbaf k, Mahoney MC. An unusual presentation of Castleman’s Disease: a case report. BMC Infectious Diseases 2003;3:20 doi:10.1186/1471-2334-3-20.
Gupta Capt MK, Magu Col SK, Behl A. Multicentric Castleman´s Disease. MJAFI 2002;58:250-252.
Modak D, Ganguly RR, Haldar SN, Samanta PS, Pramanik N, Guha SK. Castleman´s Disease in HIV infected patient from Eastern India. JAPI 2008;56.
Moss SF, Thomas DM, Mulnier C, McGill IG, Hodgson HF. Intestinal Lymphangiectasia associated with angiofollicular Lymph node hyperplasia (Castleman´s Disease). Gut 1992;33:135-137.
Yeon SH, Bae KE, Won KJ, Kyoung SB, Jin Sk, Soo BK. Complete Remission in Patient with Human Herpes Virus-8 Negative Multicentric Castleman Disease Using CHOP Chemotherapy. Cancer Res Treat 2009;41:104-107.
Bourlon-Cuellar R, Gallegos C, Zárate-Osorno A, Carrillo J, Martínez M y col. Enfermedad de Castleman: reporte de un caso. Med Int Mex 2012;28:67-72.