Utility of the Guinea pig like model of audiologyc studies and proposal of surgical accesses to the ear and neck

Emilio Arch-Tirado; Antonio Verduzco-Mendoza; Enrique Azuara-Pliego; Francisco Hernández-Orozco; Miguel Ángel Collado-Corona

2005, Number 5

<< Back Next >>

Cir Cir 2005; 73 (5)

Utility of the Guinea pig like model of audiologyc studies and proposal of surgical accesses to the ear and neck

Arch-Tirado E, Verduzco-Mendoza A, Azuara-Pliego E, Hernández-Orozco F, Collado-Corona MA

Full text

How to cite this article

Language: Spanish
References: 25
Page: 339-344
PDF size: 142.68 Kb.

ABSTRACT

We discuss the utility of the guinea pig model in audiology research and describe the different surgical accesses to the middle and inner ear in order to use these techniques for the production of experimental deafness. In addition, we describe a surgical technique for laryngeal denervation. Finally, we discuss the auditory-evoked potentials obtained in newborn and mature animals, in whom experimental deafness was produced. Our purpose was to confirm the use of the Guinea pig as an ideal model for audiologic studies and for neck surgery.

REFERENCES

Manntty AH. Cobayos. Argentina: Ed. Albatros;1976. pp. 1-6.
2. Banixs R. The Guinea Pig (Biology, Care, Identification, Nomenclature, Breeding and Genetics). USAMRIID Seminar Series;1989. pp. 10-17.
3. Nebil G, et al. Anatomy of the Guinea pig temporal bone. Ann Otorhinol Laringol 1992;101:699-704.
4. Gil-Carcedo LM, Martin MC, Carranza MA, Benito JI. Abordaje quirúrgico del oído medio del cobayo. Acta Otorrinolaringol Esp 1991;42(5):399-403.
5. Asarch R, Abramson M, Litton Word B. Surgical anatomy of the Guinea pig ear. Ann Otol 1975;84:250-255.
6. Estrada E. Alteraciones etiológicas post-mortem en el oído del cuyo. An Soc Mex Otorrinolaringol 1956;30:31-35.
7. Savin C. Lesiones cocleares experimentales con antibióticos. An Soc Mex Otorrinolaringol 1962;9(2-3):101-107.
8. Savin C. Caracteres morfológicas de los vasos del oído Interno. An Soc Mex Otorrinolaringol 1983;6(2):61-69.
9. Islas S. Datos experimentales sobre el transporte iónico entre la endo y perilinfa. An Soc Mex Otorrinolarginol 1969;12(1-3):39-49.
10. Stebbins WC. The Acoustic Sense of Animals. Cambridge, MA: Harvard University Press;1983. pp. 92-94.
11. Redies H, Sieben U, Creutzfeldt OD. Functional subdivisions in the auditory cortex of the Guinea pig. J Comp Neurol 1989;282(4):473-488.
12. Hernández-Orozco F, Flores T, Peñalosa Y. Registros electrofisio-
lógicos para el diagnóstico de la patología de la comunicación humana. México: Instituto Nacional de la Comunicación Humana; 1997. pp. 231-242.
13. Roquette GJ, Gil SM, Danino GG, Potenciales auditivos evocados del tronco cerebral en el cobayo. An ORL Iber-Am 1982;IX:371-382.
14. Arch-Tirado E, McCowan B, Saltijeral-Oaxaca J, Zarco-de Coronado I, Licona-Bonilla J. Development of isolation-induced vocal behavior in normal hearing and deafened Guinea pig infants. J Speech Lang Hear Res 2000;43(2):432-440.
15. Famula TR, Oberbauer AM, Sousa CA. A threshold model analysis of deafness in dalmatians. Mamm Genome 1966;7,650-653.
16. Holliday TA, Nelson HJ, Williams DC, Willits N. Unilateral and bilateral brainstem auditory-evoked responses abnormalities in 900 dalmatian dogs. J Vet Intern Med 1992;6:166-174.
17. Luttgen PJ. Deafness in the dog and cat. Vet Clin North Am 1994;
24:981-989.
18. Montes-de Oca FE, Saul A, Escalante UC, Poblano A, Lagunes R. El vitiligo y la audición. An Otorrinolaringol Mex 1990;35:279-281.
19. Schortt A, Spoendlin H. Pigment anomaly associated inner ear deafness. Acta Otolaryngol (Stockholm) 1987;103:451-457.
20. Strain GM, Kearney MT, Gingac IJ, Levesque DC, Nelson HJ, Tedford BC, Remsen LG. Brainstem auditory-evoked potential assessment of congenital deafness in dalmatians: associations with phenotypic markers. J Vet Intern Med 1992;5:182.
21. Collado-Corona M, Mora-Magama I, Cordero GL, Toral-Martiñon R, Shkurovich-Zaslavsky M, Uiz-García M, González-Astiazaran A. Transcranial magnetic stimulation and acoustic trauma or hearing loss in children. Neurol Res 2001;23:343-346.
22. Yoshida Y, Tanaka Y, Saito T, Shimazaki T, Hirano M. Peripheral nervous system in the larynx. Folia Phoniatr (Basel) 1992;44:194-219.
23. Guía para el cuidado y uso de los animales de laboratorio. Institute of Laboratory Animal Resources 1996. Edición Mexicana auspiciada por la Academia Nacional de Medicina.