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Academia Mexicana de Neurología, A.C.

2008, Number 4

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Rev Mex Neuroci 2008; 9 (4)

Neuropsychological evaluation in relapsing-remitting multiple sclerosis patients with low score in Kurtzke scale

Hernández B, Plascencia N, Villa MÁ, Sauri S, Quiñones S, Venegas A, Zendejas L, Islas M, Peña P, Roa P, Rojas M, Núñez L

Language: Spanish
References: 13
Page: 273-277
PDF size: 76.16 Kb.


ABSTRACT

Introduction: Some previous studies conclude that multiple sclerosis (MS) can produce diverse patterns of cognitive impairment. Objective: To evaluate the neuropsychological alterations in MS patients and correlate them with the time of evolution and a low score in Kurtzke scale. Material and methods: Patients with relapsing remitting MS with less than two years of diagnosis and ‹ 2 points in Kurtzke scale, submitted to some tests: WAIS-III, London Tower, Semantic and phonologic fluency test, Beck inventory. Results: 25-56 years old seven female, two males patients. Verbal IQ of 75-98; execution IQ of 79-94 and total IQ of 77-95. Only verbal quotients are in the media for the group of age and the others are lower. Only three subjects obtained quotients over the average. In London Tower test, 7/9 realized 49 more movements than the necessary to solve the proposed problems. In the Semantic and phonologic fluency test, only three subjects were normal. In Beck inventory one patient showed severe depression (32 points) and one mild depression. Conclusion: Cognitive dysfunction can appear early in the course of MS. Low score in Kurtzke scale does not correlate with the severity of cognitive dysfunction.


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